ES512533A0 - Un procedimiento para la preparacion de 1-(3-halo-2-piridinil)piperazinas. - Google Patents
Un procedimiento para la preparacion de 1-(3-halo-2-piridinil)piperazinas.Info
- Publication number
- ES512533A0 ES512533A0 ES512533A ES512533A ES512533A0 ES 512533 A0 ES512533 A0 ES 512533A0 ES 512533 A ES512533 A ES 512533A ES 512533 A ES512533 A ES 512533A ES 512533 A0 ES512533 A0 ES 512533A0
- Authority
- ES
- Spain
- Prior art keywords
- halo
- piridinil
- piperazines
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000004885 piperazines Chemical class 0.000 title 1
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- 206010039897 Sedation Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000674 adrenergic antagonist Substances 0.000 abstract 1
- 102000030484 alpha-2 Adrenergic Receptor Human genes 0.000 abstract 1
- 108020004101 alpha-2 Adrenergic Receptor Proteins 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000036280 sedation Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26712081A | 1981-05-26 | 1981-05-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES512533A0 true ES512533A0 (es) | 1983-06-01 |
| ES8306740A1 ES8306740A1 (es) | 1983-06-01 |
Family
ID=23017399
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES512533A Expired ES8306740A1 (es) | 1981-05-26 | 1982-05-25 | Un procedimiento para la preparacion de 1-(3-halo-2-piridinil)piperazinas. |
| ES519856A Expired ES8403477A1 (es) | 1981-05-26 | 1983-02-16 | Un procedimiento para la preparacion de 1-(3-halo-2-piridinil) piperazinas. |
| ES519855A Granted ES519855A0 (es) | 1981-05-26 | 1983-02-16 | Un procedimiento para la preparacion de 1-(3-halo-2-piridinil) piperazinas. |
| ES519854A Expired ES8403475A1 (es) | 1981-05-26 | 1983-02-16 | Un procedimiento para la preparacion de 1-(3-halo-2-piridinil) piperazinas. |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES519856A Expired ES8403477A1 (es) | 1981-05-26 | 1983-02-16 | Un procedimiento para la preparacion de 1-(3-halo-2-piridinil) piperazinas. |
| ES519855A Granted ES519855A0 (es) | 1981-05-26 | 1983-02-16 | Un procedimiento para la preparacion de 1-(3-halo-2-piridinil) piperazinas. |
| ES519854A Expired ES8403475A1 (es) | 1981-05-26 | 1983-02-16 | Un procedimiento para la preparacion de 1-(3-halo-2-piridinil) piperazinas. |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0065757B1 (es) |
| JP (1) | JPS6055068B2 (es) |
| AT (1) | ATE11134T1 (es) |
| AU (1) | AU547319B2 (es) |
| CA (1) | CA1214467A (es) |
| DE (1) | DE3261827D1 (es) |
| DK (1) | DK234282A (es) |
| ES (4) | ES8306740A1 (es) |
| FI (1) | FI821739A0 (es) |
| GR (1) | GR76413B (es) |
| IE (1) | IE53035B1 (es) |
| IL (1) | IL65802A (es) |
| NO (1) | NO821730L (es) |
| NZ (1) | NZ200642A (es) |
| PH (1) | PH18686A (es) |
| PT (1) | PT74926B (es) |
| ZA (1) | ZA823611B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH056685U (ja) * | 1991-07-09 | 1993-01-29 | 株式会社ユアサコーポレーシヨン | 電池の艤装構造 |
| US20040152710A1 (en) * | 2002-10-15 | 2004-08-05 | Deecher Darlene Coleman | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
| US7345096B2 (en) | 2002-10-15 | 2008-03-18 | Wyeth | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
| US7531543B2 (en) | 2003-10-14 | 2009-05-12 | Wyeth | Phenylpiperazine cycloalkanol derivatives and methods of their use |
| US7550485B2 (en) | 2003-10-14 | 2009-06-23 | Wyeth | Substituted N-heterocycle derivatives and methods of their use |
| US7402698B2 (en) | 2003-10-14 | 2008-07-22 | Wyeth | Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use |
| US7524846B2 (en) | 2003-10-14 | 2009-04-28 | Wyeth | Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use |
| US7365076B2 (en) | 2003-10-14 | 2008-04-29 | Wyeth | Substituted aryl cycloalkanol derivatives and methods of their use |
| US7491723B2 (en) | 2003-10-14 | 2009-02-17 | Wyeth | Alkanol and cycloalkanol-amine derivatives and methods of their use |
| US7419980B2 (en) | 2003-10-14 | 2008-09-02 | Wyeth | Fused-aryl and heteroaryl derivatives and methods of their use |
| US7414052B2 (en) | 2004-03-30 | 2008-08-19 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
| US7517899B2 (en) | 2004-03-30 | 2009-04-14 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
| CN101671297B (zh) * | 2008-09-11 | 2012-05-09 | 上海药明康德新药开发有限公司 | 4-(3-碘-2-吡啶基)哌嗪类化合物的合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773951A (en) * | 1972-12-21 | 1973-11-20 | Miles Lab | Method of treating depression with 1-(2-pyridyl)piperazine |
| US4078063A (en) * | 1976-09-24 | 1978-03-07 | Merck & Co., Inc. | Piperazinylpyridines |
-
1982
- 1982-05-12 PH PH27279A patent/PH18686A/en unknown
- 1982-05-17 FI FI821739A patent/FI821739A0/fi not_active Application Discontinuation
- 1982-05-17 IL IL65802A patent/IL65802A/xx unknown
- 1982-05-17 NZ NZ200642A patent/NZ200642A/en unknown
- 1982-05-18 AU AU83802/82A patent/AU547319B2/en not_active Ceased
- 1982-05-18 PT PT74926A patent/PT74926B/pt unknown
- 1982-05-19 AT AT82104398T patent/ATE11134T1/de not_active IP Right Cessation
- 1982-05-19 EP EP82104398A patent/EP0065757B1/en not_active Expired
- 1982-05-19 DE DE8282104398T patent/DE3261827D1/de not_active Expired
- 1982-05-21 IE IE1225/82A patent/IE53035B1/en unknown
- 1982-05-24 GR GR68235A patent/GR76413B/el unknown
- 1982-05-25 ES ES512533A patent/ES8306740A1/es not_active Expired
- 1982-05-25 ZA ZA823611A patent/ZA823611B/xx unknown
- 1982-05-25 CA CA000403610A patent/CA1214467A/en not_active Expired
- 1982-05-25 NO NO821730A patent/NO821730L/no unknown
- 1982-05-25 DK DK234282A patent/DK234282A/da not_active Application Discontinuation
- 1982-05-26 JP JP57088171A patent/JPS6055068B2/ja not_active Expired
-
1983
- 1983-02-16 ES ES519856A patent/ES8403477A1/es not_active Expired
- 1983-02-16 ES ES519855A patent/ES519855A0/es active Granted
- 1983-02-16 ES ES519854A patent/ES8403475A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK234282A (da) | 1982-11-27 |
| JPS6055068B2 (ja) | 1985-12-03 |
| AU8380282A (en) | 1982-12-02 |
| ES519854A0 (es) | 1984-03-16 |
| PH18686A (en) | 1985-08-29 |
| ATE11134T1 (de) | 1985-01-15 |
| NZ200642A (en) | 1984-11-09 |
| GR76413B (es) | 1984-08-10 |
| PT74926A (en) | 1982-06-01 |
| ES8306740A1 (es) | 1983-06-01 |
| ES8403476A1 (es) | 1984-03-16 |
| NO821730L (no) | 1982-11-29 |
| IE821225L (en) | 1982-11-26 |
| IL65802A (en) | 1985-12-31 |
| AU547319B2 (en) | 1985-10-17 |
| ES8403475A1 (es) | 1984-03-16 |
| ES519856A0 (es) | 1984-03-16 |
| PT74926B (en) | 1985-05-16 |
| IL65802A0 (en) | 1982-08-31 |
| IE53035B1 (en) | 1988-05-11 |
| EP0065757A1 (en) | 1982-12-01 |
| CA1214467A (en) | 1986-11-25 |
| ZA823611B (en) | 1983-12-28 |
| ES519855A0 (es) | 1984-03-16 |
| JPS584766A (ja) | 1983-01-11 |
| EP0065757B1 (en) | 1985-01-09 |
| FI821739A0 (fi) | 1982-05-17 |
| DE3261827D1 (en) | 1985-02-21 |
| ES8403477A1 (es) | 1984-03-16 |
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