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ES458643A1 - Un procedimiento de preparacion del 5-piridoxal-fosfato de vincamina. - Google Patents

Un procedimiento de preparacion del 5-piridoxal-fosfato de vincamina.

Info

Publication number
ES458643A1
ES458643A1 ES458643A ES458643A ES458643A1 ES 458643 A1 ES458643 A1 ES 458643A1 ES 458643 A ES458643 A ES 458643A ES 458643 A ES458643 A ES 458643A ES 458643 A1 ES458643 A1 ES 458643A1
Authority
ES
Spain
Prior art keywords
vincamine
pyridoxal
phosphate
depressive
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES458643A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes de Produits Chimiques SA
Original Assignee
Societe dEtudes de Produits Chimiques SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dEtudes de Produits Chimiques SA filed Critical Societe dEtudes de Produits Chimiques SA
Publication of ES458643A1 publication Critical patent/ES458643A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Un procedimiento de preparación del 5-piridoxal-fosfato de vincamina de la fórmula: *** consistente en hacer reaccionar en proporciones estequiométricas, a aproximadamente 105ºC, una suspensión de vincamina en una mezcla de agua y un alcanol inferior, sobre 5-piridoxal-fosfato.
ES458643A 1976-05-11 1977-05-10 Un procedimiento de preparacion del 5-piridoxal-fosfato de vincamina. Expired ES458643A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB19290/76A GB1525885A (en) 1976-05-11 1976-05-11 Vincamine salt of pyridoxal phosphate

Publications (1)

Publication Number Publication Date
ES458643A1 true ES458643A1 (es) 1978-03-16

Family

ID=10126939

Family Applications (1)

Application Number Title Priority Date Filing Date
ES458643A Expired ES458643A1 (es) 1976-05-11 1977-05-10 Un procedimiento de preparacion del 5-piridoxal-fosfato de vincamina.

Country Status (22)

Country Link
US (1) US4137316A (es)
JP (1) JPS5312413A (es)
AR (1) AR210802A1 (es)
AT (1) AT352913B (es)
AU (1) AU504254B2 (es)
BE (1) BE854437A (es)
CA (1) CA1064496A (es)
CH (1) CH602629A5 (es)
DE (1) DE2721171C3 (es)
DK (1) DK142364B (es)
EG (1) EG12663A (es)
ES (1) ES458643A1 (es)
FR (2) FR2351117A1 (es)
GB (1) GB1525885A (es)
HK (1) HK58979A (es)
IN (1) IN145671B (es)
MY (1) MY8000068A (es)
NL (1) NL170096C (es)
NZ (1) NZ183912A (es)
OA (1) OA06089A (es)
PT (1) PT66495B (es)
ZA (1) ZA772489B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56117080A (en) * 1980-02-16 1981-09-14 Kobe Steel Ltd Method of measuring location of surface layer of charge in vertical eurnace
JPS5818591B2 (ja) * 1980-02-16 1983-04-13 株式会社神戸製鋼所 竪型炉内装入物の表層位置測定装置
DE3113132A1 (de) * 1981-04-01 1982-10-21 Heinrich Mack Nachf., 7918 Illertissen Vincamin-cyclamat, verfahren zu seiner herstellung und dieses enthaltende arzneimittel
US4931002A (en) * 1987-05-29 1990-06-05 The University Of Vermont Pyridoxal-5'-phosphate as an in vitro anticoagulant for whole blood
JPH0624581U (ja) * 1992-07-13 1994-04-05 山水工業有限会社 衣服掛け
US6043259A (en) * 1998-07-09 2000-03-28 Medicure Inc. Treatment of cardiovascular and related pathologies
NZ514567A (en) 1999-03-08 2002-11-26 Medicure Inc Pyridoxal analogues for vitamin B-6 disorders
US6489345B1 (en) 1999-07-13 2002-12-03 Medicure, Inc. Treatment of diabetes and related pathologies
EP1210117A2 (en) * 1999-08-24 2002-06-05 Medicure International Inc. Compositons for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds
US7442689B2 (en) * 2000-02-29 2008-10-28 Medicure International Inc. Cardioprotective phosphonates and malonates
WO2001064692A1 (en) 2000-02-29 2001-09-07 Medicure International Inc. Cardioprotective phosphonates and malonates
US6586414B2 (en) 2000-03-28 2003-07-01 Medicure International Inc. Treatment of cerebrovascular disease
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
US6897228B2 (en) * 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
AU7226301A (en) 2000-07-07 2002-01-21 Medicure Int Inc Pyridoxine and pyridoxal analogues: cardiovascular therapeutics
US20040121988A1 (en) * 2001-03-28 2004-06-24 Medicure International Inc. Treatment of cerebrovascular disease
US20040186077A1 (en) * 2003-03-17 2004-09-23 Medicure International Inc. Novel heteroaryl phosphonates as cardioprotective agents
WO2006002549A1 (en) * 2004-07-07 2006-01-12 Medicure International Inc. Combination therapies employing platelet aggregation drugs
US20070060549A1 (en) * 2004-08-10 2007-03-15 Friesen Albert D Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders
US20060094749A1 (en) * 2004-10-28 2006-05-04 Medicure International Inc. Substituted pyridoxines as anti-platelet agents
US7459468B2 (en) * 2004-10-28 2008-12-02 Medicure International, Inc. Aryl sulfonic pyridoxines as antiplatelet agents
CA2585165A1 (en) * 2004-10-28 2006-05-18 Medicure International Inc. Dual antiplatelet/anticoagulant pyridoxine analogs
US20070149485A1 (en) * 2005-11-28 2007-06-28 Medicure International, Inc. Selected dosage for the treatment of cardiovascular and related pathologies
CA2590605A1 (en) * 2007-05-28 2008-11-28 Medicure International Inc. Improvement of mood, memory and cognitive function with pyridoxal 5'-phosphate

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2828315A (en) * 1957-01-16 1958-03-25 Merck & Co Inc Procaine salt of pyridoxal phosphate and process
FR2176516B1 (es) * 1972-03-22 1975-03-14 Synthelabo
FR2191891B1 (es) * 1972-07-13 1975-08-08 Roussel Uclaf
CH585226A5 (en) * 1974-03-08 1977-02-28 Vifor Sa Slightly soluble vincamine pamoates - with long duration of action as cerebral vasodilators
FR2275211A2 (fr) * 1974-06-19 1976-01-16 Synthelabo Nouveaux amides de l'acide dihydroapovincaminique, leurs sels, leur preparation et les medicaments qui en contiennent
FR2283669A1 (fr) * 1974-09-06 1976-04-02 Elmu Sa 2-cetoglutarate de vincamine et son procede de preparation

Also Published As

Publication number Publication date
HK58979A (en) 1979-08-31
DE2721171A1 (de) 1977-11-24
DK204877A (es) 1977-11-12
ATA320277A (de) 1979-03-15
DK142364B (da) 1980-10-20
OA06089A (fr) 1981-06-30
AU504254B2 (en) 1979-10-04
IN145671B (es) 1985-01-05
FR2350842B1 (es) 1980-05-09
DK142364C (es) 1981-03-02
BE854437A (fr) 1977-09-01
FR2350842A1 (fr) 1977-12-09
PT66495B (en) 1978-09-29
DE2721171B2 (de) 1979-10-31
PT66495A (en) 1977-05-01
AU2489477A (en) 1978-11-09
DE2721171C3 (de) 1980-07-10
AT352913B (de) 1979-10-10
CA1064496A (en) 1979-10-16
GB1525885A (en) 1978-09-20
ZA772489B (en) 1978-05-30
JPS5312413A (en) 1978-02-03
NL170096C (nl) 1982-10-01
CH602629A5 (es) 1978-07-31
AR210802A1 (es) 1977-09-15
EG12663A (en) 1979-12-31
JPS5618598B2 (es) 1981-04-30
FR2351117B1 (es) 1980-06-27
US4137316A (en) 1979-01-30
NZ183912A (en) 1978-09-25
FR2351117A1 (fr) 1977-12-09
MY8000068A (en) 1980-12-31
NL170096B (nl) 1982-05-03
NL7705129A (nl) 1977-11-15

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