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ES453100A1 - Metodo de preparar una cinamamida. - Google Patents

Metodo de preparar una cinamamida.

Info

Publication number
ES453100A1
ES453100A1 ES453100A ES453100A ES453100A1 ES 453100 A1 ES453100 A1 ES 453100A1 ES 453100 A ES453100 A ES 453100A ES 453100 A ES453100 A ES 453100A ES 453100 A1 ES453100 A1 ES 453100A1
Authority
ES
Spain
Prior art keywords
convulsant
cinnamide compounds
compounds
cinnamide
convulsions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES453100A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of ES453100A1 publication Critical patent/ES453100A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/11—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Método de preparar una cinamamida de fórmula **(Fórmula 01)** donde X es cloro, bromo o yodo, y R es hidrógeno o alcohilo que tiene 1 a 3 átomos de carbono, con tal de que R no sea hidrógeno cuando X es cloro, caracterizado porque se hace reaccionar una amina de fórmula R.NH2 con un alcohol o aldehido de fórmula (III) o (IV), respectivamente **(Fórmula 02)** donde R y X tienen los significados definidos en la fórmula (I), a una temperatura por debajo de 10ºC, en presencia de peróxido de níquel y un medio líquido inerte.
ES453100A 1974-08-09 1976-11-06 Metodo de preparar una cinamamida. Expired ES453100A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB35279/74A GB1519762A (en) 1974-08-09 1974-08-09 Cinnamamides their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ES453100A1 true ES453100A1 (es) 1978-10-16

Family

ID=10375925

Family Applications (3)

Application Number Title Priority Date Filing Date
ES440140A Expired ES440140A1 (es) 1974-08-09 1975-08-08 Metodo de preparar una cinamamida.
ES453101A Expired ES453101A1 (es) 1974-08-09 1976-11-06 Metodo de preparar una cinamamida.
ES453100A Expired ES453100A1 (es) 1974-08-09 1976-11-06 Metodo de preparar una cinamamida.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES440140A Expired ES440140A1 (es) 1974-08-09 1975-08-08 Metodo de preparar una cinamamida.
ES453101A Expired ES453101A1 (es) 1974-08-09 1976-11-06 Metodo de preparar una cinamamida.

Country Status (27)

Country Link
US (1) US4041071A (es)
JP (1) JPS588387B2 (es)
AR (2) AR213275A1 (es)
AT (2) AT350531B (es)
AU (1) AU498222B2 (es)
BE (1) BE832283A (es)
CA (1) CA1075714A (es)
CH (3) CH616650A5 (es)
CS (1) CS209864B2 (es)
CY (1) CY1110A (es)
DD (1) DD123311A5 (es)
DE (1) DE2535599C2 (es)
DK (1) DK360975A (es)
ES (3) ES440140A1 (es)
FI (1) FI752257A (es)
FR (1) FR2281109A1 (es)
GB (1) GB1519762A (es)
HK (1) HK20881A (es)
HU (1) HU174875B (es)
IE (1) IE41444B1 (es)
IL (1) IL47892A (es)
IT (1) IT8047984A0 (es)
NL (1) NL7509482A (es)
PL (5) PL118454B1 (es)
SE (1) SE424316B (es)
SU (1) SU728712A3 (es)
ZA (1) ZA755127B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190674A (en) * 1976-02-03 1980-02-26 Burroughs Wellcome Co. 3-Fluoro-N-cyclopropylcinnamide
US4107320A (en) * 1976-08-06 1978-08-15 Burroughs Wellcome Co. Biologically active amides
US4183858A (en) * 1977-07-01 1980-01-15 Merrell Toraude Et Compagnie α-Vinyl tryptophanes
US4179524A (en) * 1978-06-16 1979-12-18 Burroughs Wellcome Co. Biologically active amide
DE4421536A1 (de) * 1994-06-20 1995-12-21 Hoechst Ag Perfluoralkylgruppen tragende phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
KR100492809B1 (ko) * 2001-11-23 2005-06-03 한국화학연구원 항산화 활성을 갖는 4-히드록시 신남아미드 유도체, 그의제조방법 및 이를 포함하는 약학적 조성물
PL209602B1 (pl) 2005-10-20 2011-09-30 Inst Chemii Bioorg Pan Sposób otrzymywania amidu kwasu 3-(4-hydroksyfenylo)propanowego

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1131728A (en) 1966-05-10 1968-10-23 Smith Kline French Lab N,n-dimethylcinnamamides
GB1128142A (en) 1966-06-30 1968-09-25 James Lincoln Bezemek Wear indicating arrangement for vehicle power transfer devices
US3444197A (en) 1966-09-27 1969-05-13 Upjohn Co 3,4-dihalocinnamamides
US3538156A (en) 1967-07-24 1970-11-03 Herbert Schwartz Cinnamamides
CH533113A (de) * 1967-12-01 1973-03-15 Thomae Gmbh Dr K Verfahren zur Herstellung von neuen Zimtsäureamiden
US3488749A (en) * 1968-01-29 1970-01-06 Smithkline Corp Antidepressant n,n-dimethylcinnamamide compositions and methods
CH510021A (de) 1968-11-05 1971-07-15 Thomae Gmbh Dr K Verfahren zur Herstellung neuer Zimtsäureamide
FR2040181A1 (es) * 1969-04-02 1971-01-22 Lipha
CA1174865A (en) 1971-04-16 1984-09-25 Ferenc M. Pallos Thiolcarbamate herbicides containing nitrogen containing antidote

Also Published As

Publication number Publication date
FR2281109B1 (es) 1978-11-10
AR211436Q (es) 1977-12-30
CS209864B2 (en) 1981-12-31
IL47892A0 (en) 1975-11-25
ATA61977A (de) 1978-03-15
DD123311A5 (es) 1976-12-12
JPS588387B2 (ja) 1983-02-15
HK20881A (en) 1981-05-22
SE424316B (sv) 1982-07-12
PL101781B1 (pl) 1979-01-31
CA1075714A (en) 1980-04-15
AU498222B2 (en) 1979-02-22
FR2281109A1 (fr) 1976-03-05
FI752257A (es) 1976-02-10
PL118238B1 (en) 1981-09-30
NL7509482A (nl) 1976-02-11
CH636339A5 (de) 1983-05-31
US4041071A (en) 1977-08-09
IT8047984A0 (it) 1980-02-22
IL47892A (en) 1978-04-30
ZA755127B (en) 1977-03-30
IE41444L (en) 1976-02-09
AU8378975A (en) 1977-02-10
AT346314B (de) 1978-11-10
CY1110A (en) 1981-12-04
SU728712A3 (ru) 1980-04-15
PL118454B1 (en) 1981-10-31
BE832283A (fr) 1976-02-09
CH639067A5 (de) 1983-10-31
ATA618175A (de) 1978-11-15
CH616650A5 (es) 1980-04-15
PL110755B1 (en) 1980-07-31
HU174875B (hu) 1980-03-28
AR213275A1 (es) 1979-01-15
AT350531B (de) 1979-06-11
DE2535599A1 (de) 1976-02-26
SE7508936L (sv) 1976-02-10
GB1519762A (en) 1978-08-02
DK360975A (da) 1976-02-10
DE2535599C2 (de) 1985-07-11
PL101758B1 (pl) 1979-01-31
ES453101A1 (es) 1978-03-01
ES440140A1 (es) 1977-06-01
IE41444B1 (en) 1980-01-02
JPS5141340A (es) 1976-04-07

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