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ES411222A1 - Alpha.alpha-diarylimidazole-2-methanols - Google Patents

Alpha.alpha-diarylimidazole-2-methanols

Info

Publication number
ES411222A1
ES411222A1 ES411222A ES411222A ES411222A1 ES 411222 A1 ES411222 A1 ES 411222A1 ES 411222 A ES411222 A ES 411222A ES 411222 A ES411222 A ES 411222A ES 411222 A1 ES411222 A1 ES 411222A1
Authority
ES
Spain
Prior art keywords
group
halogen
alpha
trifluoromethyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES411222A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gist Brocades NV
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Publication of ES411222A1 publication Critical patent/ES411222A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Procedure for obtaining alpha, alpha-diaryl-imidazol-2-methanoles, of general formula ** formula ** in which R1-R10, which may be the same or different, each represent a hydrogen or halogen atom or a trifluoromethyl or tert-butyl group, provided that at least one of said radicals is halogen, trifluormethyl or tert-butyl, R11 and R12 which may be the same or different, each represent a hydrogen atom, a lower alkyl group, a phenyl group or a phenyl group substituted by halogen or trifluoromethyl, and R13 represents a hydrogen atom or a lower alkyl group, a (lower) alkoxy methyl group, a phenylalkyl group (optionally substituted in the phenyl moiety by one or more atoms of halogen or alkyl or trifluoromethyl groups), an alkenyl group, a phenylalkyl (lower) methyl group (optionally substituted in the phenyl moiety by one or more halogen atoms or an alkyl or trifluoromethyl group), or a benzene group nosulfonyl (in which the phenyl moiety is optionally substituted by one or more alkyl groups (Machine-translation by Google Translate, not legally binding)
ES411222A 1972-02-04 1973-02-02 Alpha.alpha-diarylimidazole-2-methanols Expired ES411222A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB541872 1972-02-04
GB541872A GB1363382A (en) 1972-02-04 1972-09-05 Alpha.alpha-diarylimidazole-2-methanols

Publications (1)

Publication Number Publication Date
ES411222A1 true ES411222A1 (en) 1975-12-01

Family

ID=26239878

Family Applications (1)

Application Number Title Priority Date Filing Date
ES411222A Expired ES411222A1 (en) 1972-02-04 1973-02-02 Alpha.alpha-diarylimidazole-2-methanols

Country Status (16)

Country Link
AT (1) AT322545B (en)
AU (1) AU467008B2 (en)
BE (1) BE794940A (en)
CA (1) CA979899A (en)
CH (1) CH594630A5 (en)
CS (1) CS187368B2 (en)
DE (1) DE2305212A1 (en)
ES (1) ES411222A1 (en)
FI (1) FI57936C (en)
FR (1) FR2173984B1 (en)
GB (1) GB1363382A (en)
HU (1) HU166406B (en)
IL (1) IL41448A (en)
LU (1) LU66953A1 (en)
NL (1) NL7301494A (en)
NO (1) NO137233C (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19951701A1 (en) * 1999-10-27 2001-05-03 Aventis Pharma Gmbh Use of 2-imidazolyl-substituted carbinols for the manufacture of a medicament for the treatment or prophylaxis of diseases caused by ischemic conditions
WO2008118319A2 (en) * 2007-03-23 2008-10-02 Merck & Co., Inc. Mineralocorticoid receptor modulators

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2899441A (en) * 1959-08-11 Chjchjoh

Also Published As

Publication number Publication date
CH594630A5 (en) 1978-01-13
AU5177473A (en) 1974-08-08
CS187368B2 (en) 1979-01-31
FI57936C (en) 1980-11-10
NO137233B (en) 1977-10-17
FR2173984A1 (en) 1973-10-12
DE2305212A1 (en) 1973-08-16
AT322545B (en) 1975-05-26
GB1363382A (en) 1974-08-14
NO137233C (en) 1978-01-25
IL41448A0 (en) 1973-04-30
IL41448A (en) 1977-07-31
FR2173984B1 (en) 1976-08-13
BE794940A (en) 1973-08-02
NL7301494A (en) 1973-08-07
LU66953A1 (en) 1973-04-19
CA979899A (en) 1975-12-16
HU166406B (en) 1975-03-28
AU467008B2 (en) 1975-11-13
FI57936B (en) 1980-07-31

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