ES410163A1 - A procedure for preparing 2- (6-metoxy-2-nafthy) propionic acid. (Machine-translation by Google Translate, not legally binding)
- Google Patents
A procedure for preparing 2- (6-metoxy-2-nafthy) propionic acid. (Machine-translation by Google Translate, not legally binding)
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Palo Alto LLC
Original Assignee
Roche Palo Alto LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Palo Alto LLCfiledCriticalRoche Palo Alto LLC
Publication of ES410163A1publicationCriticalpatent/ES410163A1/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
A process for preparing 2- (6-methoxy-2-naphthyl) propionic acid consisting of: A) reacting a 2-halo-6-methoxyphene, where the halogen is chlorine, bromine or iodine, with a metal selected from lithium and magnesium, in an ethereal solvent, followed by treatment with a copper halide (I) or of cadmium, respectively, to give the corresponding copper or cadmium compound of 2-halo-6-methoxynaphthalene; B) reacting 2-halo-6-methoxynaphthyl-copper or -cadmium with an excess of a lower alkyl 2-halopropionate in an inert solvent, until a 2- (6-methoxy-2-naphthyl) propionate is formed of lower alkyl, where the halogen is bromine, chlorine or iodine; C) hydrolyzing the ester group of 2- (6-methoxy-2-naphthyl) propionate; y D) recover 2- (6-methoxy-2-naphthyl) propionic acid from the reaction mixture and solve it to obtain d 2- (6-methoxy-2-naphthyl) propionic acid. (Machine-translation by Google Translate, not legally binding)
ES410163A1969-09-301972-12-29A procedure for preparing 2- (6-metoxy-2-nafthy) propionic acid. (Machine-translation by Google Translate, not legally binding)
ExpiredES410163A1
(en)
A process for the preparation of acids 2- (6-metoxy2'naftil) propionico and 2- (6-metoxy-2-naftil) -1-propanol. (Machine-translation by Google Translate, not legally binding)
Procedure for the obtaining of N-halogenoacetilaminas, irreversible inhibitors of catecol-o-methyltransferase. (Machine-translation by Google Translate, not legally binding)