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Wander AG
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Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms
(AREA)
Abstract
Process for the production of oxazepine derivatives, of formula I, **(See formula)** wherein A is selected from sulfur and a sulfonyl group; R1 is selected from hydrogen, alkyl of 1 to 3 carbon atoms, hydroxyalkyl of 1 to 3 carbon atoms, acetoxyalkyl, where the alkyl is 1 to 3 carbon atoms, and alkoxyalkyl with a total of at most 6 atoms carbon, characterized in that it comprises reacting a compound of formula II, **(See formula)** where A has the meaning indicated above, and X is a reactive group capable of being dissociated with the hydrogen in the nitrogen atom of a piperazine, with X being preferably chosen from halogen, sulfhydryl, alkoxy or alkylthio of 1 to 5 carbon atoms, p-nitrobenzylthio or tosyl with a compound of formula III, **(See formula)** where R1 has the meaning indicated above. (Machine-translation by Google Translate, not legally binding)
ES382423A1969-08-201970-08-04Procedure for the production of oxacepine derivatives. (Machine-translation by Google Translate, not legally binding)
ExpiredES382423A1
(en)