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ES372635A1 - Procedure for the preparation of l-asparaginase (aspara-ginase x) partially demissed. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of l-asparaginase (aspara-ginase x) partially demissed. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES372635A1
ES372635A1 ES372635A ES372635A ES372635A1 ES 372635 A1 ES372635 A1 ES 372635A1 ES 372635 A ES372635 A ES 372635A ES 372635 A ES372635 A ES 372635A ES 372635 A1 ES372635 A1 ES 372635A1
Authority
ES
Spain
Prior art keywords
asparaginase
partially
demissed
ginase
aspara
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES372635A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19681803782 external-priority patent/DE1803782A1/en
Priority claimed from DE19691920045 external-priority patent/DE1920045A1/en
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES372635A1 publication Critical patent/ES372635A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/82—Asparaginase (3.5.1.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Partially de - aminated L - asparaginase (claimed per se) is prepared by treating L- asparaginase with nitrous acid. The nitrous acid may be produced in situ from a nitrite. The reaction may take place in aqueous or aqueous-organic media, and may be stopped when sufficient deamination has taken place by adding urea.
ES372635A 1968-10-18 1969-10-17 Procedure for the preparation of l-asparaginase (aspara-ginase x) partially demissed. (Machine-translation by Google Translate, not legally binding) Expired ES372635A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19681803782 DE1803782A1 (en) 1968-10-18 1968-10-18 Partially deaminated l-asparaginase
DE19691920045 DE1920045A1 (en) 1969-04-19 1969-04-19 Partially deaminated l-asparaginase

Publications (1)

Publication Number Publication Date
ES372635A1 true ES372635A1 (en) 1972-03-01

Family

ID=25756288

Family Applications (1)

Application Number Title Priority Date Filing Date
ES372635A Expired ES372635A1 (en) 1968-10-18 1969-10-17 Procedure for the preparation of l-asparaginase (aspara-ginase x) partially demissed. (Machine-translation by Google Translate, not legally binding)

Country Status (8)

Country Link
AT (1) AT289688B (en)
BE (1) BE740442A (en)
ES (1) ES372635A1 (en)
FR (1) FR2021047B1 (en)
GB (1) GB1229566A (en)
IL (1) IL33207A0 (en)
LU (1) LU59654A1 (en)
NL (1) NL6915697A (en)

Also Published As

Publication number Publication date
FR2021047A1 (en) 1970-07-17
FR2021047B1 (en) 1973-01-12
NL6915697A (en) 1970-04-21
LU59654A1 (en) 1970-01-12
GB1229566A (en) 1971-04-28
IL33207A0 (en) 1969-12-31
AT289688B (en) 1971-05-10
BE740442A (en) 1970-04-17

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