ES2808853T3 - Cadenas ligeras comunes y procedimientos de uso - Google Patents
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- ES2808853T3 ES2808853T3 ES15797972T ES15797972T ES2808853T3 ES 2808853 T3 ES2808853 T3 ES 2808853T3 ES 15797972 T ES15797972 T ES 15797972T ES 15797972 T ES15797972 T ES 15797972T ES 2808853 T3 ES2808853 T3 ES 2808853T3
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US20090162359A1 (en) | 2007-12-21 | 2009-06-25 | Christian Klein | Bivalent, bispecific antibodies |
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CA2825081A1 (en) | 2011-02-28 | 2012-09-07 | Birgit Bossenmaier | Antigen binding proteins |
AR085403A1 (es) | 2011-02-28 | 2013-09-25 | Hoffmann La Roche | Proteinas monovalentes que se unen a antigenos |
JP6159724B2 (ja) | 2011-08-23 | 2017-07-05 | ロシュ グリクアート アーゲー | T細胞活性化抗原に対して特異的な二重特異性抗体及び腫瘍抗原および使用方法 |
EP2904016B1 (en) | 2012-10-08 | 2018-11-14 | Roche Glycart AG | Fc-free antibodies comprising two fab-fragments and methods of use |
KR20150122761A (ko) | 2013-02-26 | 2015-11-02 | 로슈 글리카트 아게 | T 세포 활성화 항원 결합 분자 |
CN110437337B (zh) | 2013-02-26 | 2024-07-30 | 罗切格利卡特公司 | 双特异性t细胞活化性抗原结合分子 |
EP3055329B1 (en) * | 2013-10-11 | 2018-06-13 | F. Hoffmann-La Roche AG | Multispecific domain exchanged common variable light chain antibodies |
SI3608337T1 (sl) | 2014-08-04 | 2024-07-31 | F. Hoffmann - La Roche Ag | Biospecifične molekule za aktivacijo celic T in antigensko vezavo |
AU2015348595B2 (en) | 2014-11-20 | 2021-06-10 | F. Hoffmann-La Roche Ag | T cell activating bispecific antigen binding molecules against FOLR1 and CD3 |
EP3747905A1 (en) | 2014-11-20 | 2020-12-09 | F. Hoffmann-La Roche AG | Common light chains and methods of use |
KR20240024318A (ko) | 2014-11-20 | 2024-02-23 | 에프. 호프만-라 로슈 아게 | T 세포 활성화 이중특이적 항원 결합 분자 CD3 ABD 엽산 수용체 1(FolR1) 및 PD-1 축 결합 길항물질의 조합 요법 |
BR112017024757A2 (pt) | 2015-05-18 | 2018-11-13 | TCR2 Therapeutics Inc. | composições e métodos para reprogramação de tcr utilizando proteínas de fusão |
AR106188A1 (es) | 2015-10-01 | 2017-12-20 | Hoffmann La Roche | Anticuerpos anti-cd19 humano humanizados y métodos de utilización |
EP3356410B1 (en) | 2015-10-02 | 2021-10-20 | F. Hoffmann-La Roche AG | Bispecific anti-ceaxcd3 t cell activating antigen binding molecules |
CN108290954B (zh) | 2015-12-09 | 2022-07-26 | 豪夫迈·罗氏有限公司 | Ii型抗cd20抗体用于降低抗药物抗体形成 |
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KR20180107111A (ko) | 2016-02-17 | 2018-10-01 | 시애틀 지네틱스, 인크. | 암 및 면역학적 장애를 치료하기 위한 bcma 항체 및 이의 용도 |
CA3016563A1 (en) | 2016-03-21 | 2017-09-28 | Elstar Therapeutics, Inc. | Multispecific and multifunctional molecules and uses thereof |
UA127308C2 (uk) | 2016-03-22 | 2023-07-19 | Ф. Хоффманн-Ля Рош Аг | Активована протеазою біспецифічна молекула, яка зв'язує т-клітини |
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BR112018076767A2 (pt) * | 2016-06-21 | 2019-04-02 | Teneobio, Inc. | anticorpos de ligação a cd3 |
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EP3500301B1 (en) * | 2016-08-16 | 2023-08-30 | Epimab Biotherapeutics Inc. | Monovalent asymmetric tandem fab bispecific antibodies |
DK4050034T3 (da) * | 2016-09-14 | 2024-06-03 | Teneoone Inc | Cd3-bindende antistoffer |
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WO2018139623A1 (en) * | 2017-01-30 | 2018-08-02 | Chugai Seiyaku Kabushiki Kaisha | Anti-sclerostin antibodies and methods of use |
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2015
- 2015-11-17 EP EP20170514.2A patent/EP3747905A1/en not_active Withdrawn
- 2015-11-17 WO PCT/EP2015/076745 patent/WO2016079081A1/en active Application Filing
- 2015-11-17 SI SI201531309T patent/SI3221357T1/sl unknown
- 2015-11-17 RU RU2017121326A patent/RU2747011C2/ru active
- 2015-11-17 KR KR1020177016927A patent/KR20170087486A/ko active Pending
- 2015-11-17 PT PT157979725T patent/PT3221357T/pt unknown
- 2015-11-17 EP EP15797972.5A patent/EP3221357B1/en active Active
- 2015-11-17 LT LTEP15797972.5T patent/LT3221357T/lt unknown
- 2015-11-17 BR BR112017010513-6A patent/BR112017010513A2/pt not_active Application Discontinuation
- 2015-11-17 CA CA2968162A patent/CA2968162A1/en active Pending
- 2015-11-17 JP JP2017527369A patent/JP7164949B2/ja active Active
- 2015-11-17 MX MX2017006626A patent/MX381724B/es unknown
- 2015-11-17 ES ES15797972T patent/ES2808853T3/es active Active
- 2015-11-17 HU HUE15797972A patent/HUE049650T2/hu unknown
- 2015-11-17 DK DK15797972.5T patent/DK3221357T3/da active
- 2015-11-17 RS RS20200886A patent/RS60615B1/sr unknown
- 2015-11-17 CN CN201580073564.0A patent/CN107207609B/zh active Active
- 2015-11-17 PL PL15797972T patent/PL3221357T3/pl unknown
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2017
- 2017-05-19 US US15/600,015 patent/US20170253670A1/en not_active Abandoned
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2018
- 2018-03-12 HK HK18103433.9A patent/HK1244011A1/zh unknown
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2019
- 2019-08-15 US US16/541,258 patent/US20200172633A1/en not_active Abandoned
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2020
- 2020-07-23 HR HRP20201156TT patent/HRP20201156T1/hr unknown
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2021
- 2021-04-28 JP JP2021075649A patent/JP2021129564A/ja active Pending
- 2021-09-09 US US17/470,778 patent/US12103982B2/en active Active
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CN107207609A (zh) | 2017-09-26 |
CN107207609B (zh) | 2022-07-19 |
WO2016079081A1 (en) | 2016-05-26 |
MX2017006626A (es) | 2017-08-21 |
US20200172633A1 (en) | 2020-06-04 |
JP2018504092A (ja) | 2018-02-15 |
JP2021129564A (ja) | 2021-09-09 |
PT3221357T (pt) | 2020-07-28 |
JP7164949B2 (ja) | 2022-11-02 |
CA2968162A1 (en) | 2016-05-26 |
BR112017010513A2 (pt) | 2018-04-03 |
LT3221357T (lt) | 2020-08-25 |
DK3221357T3 (da) | 2020-08-10 |
RU2017121326A (ru) | 2018-12-20 |
KR20170087486A (ko) | 2017-07-28 |
SI3221357T1 (sl) | 2020-09-30 |
HK1244011A1 (zh) | 2018-07-27 |
MX381724B (es) | 2025-03-13 |
RS60615B1 (sr) | 2020-08-31 |
US12103982B2 (en) | 2024-10-01 |
EP3221357B1 (en) | 2020-06-03 |
US20170253670A1 (en) | 2017-09-07 |
RU2747011C2 (ru) | 2021-04-23 |
HUE049650T2 (hu) | 2020-11-30 |
HRP20201156T1 (hr) | 2020-11-13 |
EP3221357A1 (en) | 2017-09-27 |
PL3221357T3 (pl) | 2020-11-02 |
US20220213224A1 (en) | 2022-07-07 |
RU2017121326A3 (pt) | 2019-06-14 |
EP3747905A1 (en) | 2020-12-09 |
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