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ES276073A1 - Procedure for the preparation of new derivatives of oxazolidinone (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new derivatives of oxazolidinone (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES276073A1
ES276073A1 ES276073A ES276073A ES276073A1 ES 276073 A1 ES276073 A1 ES 276073A1 ES 276073 A ES276073 A ES 276073A ES 276073 A ES276073 A ES 276073A ES 276073 A1 ES276073 A1 ES 276073A1
Authority
ES
Spain
Prior art keywords
represent
group
radicals
see formula
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES276073A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Publication of ES276073A1 publication Critical patent/ES276073A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Preparation procedure of the new oxaxolidinone-2 derivatives, of general formula: **(See formula)** in which: a) each one of R1, R2, R3, R4 can represent, respectively, a hydrogen atom, a lower alcoholic residue, such as methyl, ethyl, propyl, butyl, being able to constitute especially two radicals R1, R2 or R3, R4 a polymethylene chain - (CH2) n-, comprising from 2 to 6 carbon atoms; an aralcohyl moiety, such as benzyl, phenethyl, phenyl isopropyl; a cycloalkyl residue, such as cyclopropyl, cyclopentyl, diclohexyl, cycloheptyl, optionally substituted by a lower alcohol group up to C4; a phenyl or thionyl group, optionally substituted by halogen atoms, such as F, Cl, Br, with radicals such as CF3, OH, NO2, NH2, lower alkoxy or methylene dioxy; b) X can represent an oxygen atom, a sulfur atom or a -NH- group; c) A can represent a straight or branched alkane chain, having from 2 to 5 carbon atoms, such as: **(See formula)** d) Z can represent an aliphatic amine moiety such as: **(See formula)** or heterocyclic such as: piperidino, morpholino, pyrrolidino, N-methyl-piperazino, N-piperonil-piperazino, or the like, said procedures being characterized in that an acid chloride is reacted, eventually under the cis or trans configuration, racemic or optically active, of general formula: **(See formula)** on a basic compound of the general formula Y-AZ (in which Y represents an OH or NH2 group, the radicals R, Z and A having the aforementioned meanings), in solution in an organic solvent, at a low temperature . (Machine-translation by Google Translate, not legally binding)
ES276073A 1961-04-04 1962-04-02 Procedure for the preparation of new derivatives of oxazolidinone (Machine-translation by Google Translate, not legally binding) Expired ES276073A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR857672A FR1301267A (en) 1961-04-04 1961-04-04 New derivatives of oxazolidinone-2 and their preparation methods

Publications (1)

Publication Number Publication Date
ES276073A1 true ES276073A1 (en) 1962-07-01

Family

ID=8752294

Family Applications (1)

Application Number Title Priority Date Filing Date
ES276073A Expired ES276073A1 (en) 1961-04-04 1962-04-02 Procedure for the preparation of new derivatives of oxazolidinone (Machine-translation by Google Translate, not legally binding)

Country Status (5)

Country Link
CH (1) CH401059A (en)
DE (1) DE1289846B (en)
DK (1) DK102862C (en)
ES (1) ES276073A1 (en)
FR (1) FR1301267A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081582A1 (en) * 1970-03-24 1971-12-10 Delalande Sa 3-1 substd-amino-carbonyl)-5-phenyl-oxa-zoli
FR2125175A2 (en) * 1971-02-17 1972-09-29 Delalande Sa 3-1 substd-amino-carbonyl)-5-phenyl-oxa-zoli
FR2191889A1 (en) * 1972-07-13 1974-02-08 Delalande Sa 4,4,5-Triphenyl-oxazolidin-2-one derivs - analgesics, antiinflammatories and sedatives from triphenyl-amino-ethanols with ethyl carbonate
JPS6183170A (en) * 1984-09-28 1986-04-26 Nippon Chemiphar Co Ltd Novel 1,3-oxazolidin-2-one derivative and its preparation

Also Published As

Publication number Publication date
FR1301267A (en) 1962-08-17
DK102862C (en) 1965-10-18
DE1289846B (en) 1969-02-27
CH401059A (en) 1965-10-31

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