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ES2706008B8 - Procedimiento para la preparacion de una composicion a partir del cardo mariano y composicion obtenida - Google Patents

Procedimiento para la preparacion de una composicion a partir del cardo mariano y composicion obtenida

Info

Publication number
ES2706008B8
ES2706008B8 ES201830854A ES201830854A ES2706008B8 ES 2706008 B8 ES2706008 B8 ES 2706008B8 ES 201830854 A ES201830854 A ES 201830854A ES 201830854 A ES201830854 A ES 201830854A ES 2706008 B8 ES2706008 B8 ES 2706008B8
Authority
ES
Spain
Prior art keywords
composition
procedure
preparation
marian
thistle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES201830854A
Other languages
English (en)
Other versions
ES2706008B2 (es
ES2706008A1 (es
Inventor
Prous Santiago Rull
Daltell Anna Mula
Gonzalez Agustin Villar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euromed SA
Original Assignee
Euromed SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euromed SA filed Critical Euromed SA
Publication of ES2706008A1 publication Critical patent/ES2706008A1/es
Publication of ES2706008B2 publication Critical patent/ES2706008B2/es
Application granted granted Critical
Publication of ES2706008B8 publication Critical patent/ES2706008B8/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2300/00Processes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2300/00Processes
    • A23V2300/14Extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/17Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/35Extraction with lipophilic solvents, e.g. Hexane or petrol ether
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Physiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Fats And Perfumes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES201830854A 2017-09-22 2018-08-30 Procedimiento para la preparacion de una composicion a partir del cardo mariano y composicion obtenida Active ES2706008B8 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762562293P 2017-09-22 2017-09-22

Publications (3)

Publication Number Publication Date
ES2706008A1 ES2706008A1 (es) 2019-03-27
ES2706008B2 ES2706008B2 (es) 2021-06-16
ES2706008B8 true ES2706008B8 (es) 2021-07-12

Family

ID=64664793

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201830854A Active ES2706008B8 (es) 2017-09-22 2018-08-30 Procedimiento para la preparacion de una composicion a partir del cardo mariano y composicion obtenida

Country Status (14)

Country Link
US (1) US11819528B2 (es)
EP (1) EP3684390A1 (es)
JP (1) JP2020535132A (es)
KR (1) KR102469114B1 (es)
CN (1) CN111107862A (es)
AU (1) AU2018336098B2 (es)
BR (1) BR112020004948B8 (es)
CA (1) CA3075936A1 (es)
ES (1) ES2706008B8 (es)
MX (1) MX2020002549A (es)
NZ (1) NZ762913A (es)
PH (1) PH12020550098A1 (es)
RU (1) RU2020111823A (es)
WO (1) WO2019058179A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111841501A (zh) * 2020-06-23 2020-10-30 五邑大学 一种治疗炎症性疾病的药物组合物及其应用
CN111714454A (zh) * 2020-07-22 2020-09-29 宿迁医美科技有限公司 紫苏籽油与水飞蓟籽油复配的脂肪乳剂及制备方法
KR102568412B1 (ko) 2022-05-18 2023-08-18 한국자연한방 주식회사 실리마린 생체이용률이 증대된 밀크씨슬 추출물 제조방법
KR102582322B1 (ko) 2023-03-27 2023-09-26 (주)이너네이쳐 밀크씨슬 추출물이 포함되는 간 보호용 건강기능식품 조성물 및 이의 제조방법
KR102669644B1 (ko) * 2023-06-27 2024-05-27 한국자연한방 주식회사 실리마린 생체이용률이 증대된 밀크씨슬 추출물을 포함하는 지방간 개선, 예방 또는 치료용 조성물

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2181188A5 (en) * 1972-04-20 1973-11-30 Dott Inverni Della Beffa Polyhydroxyphenylchromones - by solvent extn of non-defatted fruit of Silybum marianum
DE2914330A1 (de) 1979-04-09 1980-10-30 Madaus & Co Dr Verfahren zur gewinnung von silymarin aus pflanzen
JPS5764688A (en) * 1980-10-08 1982-04-19 Madaus & Co Dr Method of obtaining silymarin from plant
DE3225688A1 (de) 1982-07-09 1984-01-12 Suschnik Matthias Dr Verfahren zur gewinnung von silymarin aus silybum marianum
RU2099076C1 (ru) * 1996-04-16 1997-12-20 Научно-производственное объединение "Всероссийский научно-исследовательский институт лекарственных и ароматических растений" Способ комплексной переработки плодов расторопши пятнистой
KR100342942B1 (ko) * 1999-07-05 2002-07-02 민경윤 카르두스 마리아누스 추출물 또는 이로부터 정제된 실리빈을함유하는 경구용 마이크로에멀젼 조성물
CZ293046B6 (cs) 2000-11-27 2004-01-14 Naturprodukt Cz Spol. S R.O. Potravní doplněk s účinkem na plazmové lipidy a antioxidační kapacitu krve
CZ292832B6 (cs) * 2001-08-30 2003-12-17 Ivax Pharmaceuticals S.R.O. Způsob přípravy silymarinu se zvýšenou rozpustností
DE102008039271A1 (de) 2007-12-23 2009-06-25 Euromed Sa Neuer Mariendistelextrakt, Verfahren zur Herstellung und Verwendung
CA2761656C (en) * 2009-05-14 2017-02-07 Lucio Claudio Rovati Amorphous silibinin for the treatment of viral hepatitis
WO2013124700A2 (en) * 2012-02-24 2013-08-29 University Of Debrecen Composition containing hepatoprotective sylibum marianum seed oil and procedure for preparation of seed oil
CN103641821B (zh) * 2013-11-25 2019-03-22 宁波绿之健药业有限公司 一种高含量低溶残的水飞蓟提取物的制备方法
CN107698572A (zh) * 2016-07-29 2018-02-16 内蒙古昶辉生物科技股份有限公司 一种水飞蓟素的提取方法
CN107663200A (zh) * 2016-07-29 2018-02-06 内蒙古昶辉生物科技股份有限公司 一种使用乙酸乙酯的水飞蓟素梯度提取方法
CN107663201A (zh) * 2016-07-29 2018-02-06 内蒙古昶辉生物科技股份有限公司 一种使用乙醇提取水飞蓟素的方法
CN107595910A (zh) * 2017-09-08 2018-01-19 江苏中兴药业有限公司 一种水飞蓟油组合物及其应用

Also Published As

Publication number Publication date
PH12020550098A1 (en) 2020-09-14
CN111107862A (zh) 2020-05-05
KR20200057006A (ko) 2020-05-25
US20190091273A1 (en) 2019-03-28
US11819528B2 (en) 2023-11-21
CA3075936A1 (en) 2019-03-28
JP2020535132A (ja) 2020-12-03
AU2018336098A1 (en) 2020-04-23
BR112020004948B1 (pt) 2023-07-18
KR102469114B1 (ko) 2022-11-18
ES2706008B2 (es) 2021-06-16
EP3684390A1 (en) 2020-07-29
WO2019058179A1 (en) 2019-03-28
NZ762913A (en) 2024-12-20
ES2706008A1 (es) 2019-03-27
BR112020004948A2 (pt) 2020-09-15
MX2020002549A (es) 2020-07-20
RU2020111823A3 (es) 2021-10-22
BR112020004948B8 (pt) 2024-03-05
AU2018336098B2 (en) 2023-09-07
RU2020111823A (ru) 2021-10-22
AU2018336098A8 (en) 2020-04-30

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