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ES261517A1 - Hydroxy amino acid derivatives - Google Patents

Hydroxy amino acid derivatives

Info

Publication number
ES261517A1
ES261517A1 ES0261517A ES261517A ES261517A1 ES 261517 A1 ES261517 A1 ES 261517A1 ES 0261517 A ES0261517 A ES 0261517A ES 261517 A ES261517 A ES 261517A ES 261517 A1 ES261517 A1 ES 261517A1
Authority
ES
Spain
Prior art keywords
alkali metal
amino acid
acid derivatives
hydroxy amino
therapeutic compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0261517A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Frosst Canada and Co
Original Assignee
Charles E Frosst and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charles E Frosst and Co filed Critical Charles E Frosst and Co
Publication of ES261517A1 publication Critical patent/ES261517A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises the D, the L, and the DL forms of N-dichloroacetylserine the alkali metal salts thereof the preparation thereof from an alkali metal salt of the serine and dichloro acetyl chloride in alkaline medium, followed by separation of the alkali metal salt product, or by acidification and extraction of the free-acid product and therapeutic compositions containing the above compounds. Therapeutic compositions may be administered orally, parenterally, or topically, and are useful as diuretics and in causing regression of certain tumours.
ES0261517A 1959-10-12 1960-09-27 Hydroxy amino acid derivatives Expired ES261517A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84559859A 1959-10-12 1959-10-12

Publications (1)

Publication Number Publication Date
ES261517A1 true ES261517A1 (en) 1960-11-16

Family

ID=25295605

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0261517A Expired ES261517A1 (en) 1959-10-12 1960-09-27 Hydroxy amino acid derivatives

Country Status (4)

Country Link
BE (1) BE595345A (en)
CH (1) CH395128A (en)
ES (1) ES261517A1 (en)
GB (1) GB899781A (en)

Also Published As

Publication number Publication date
CH395128A (en) 1965-07-15
GB899781A (en) 1962-06-27
BE595345A (en) 1961-03-23

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