[go: up one dir, main page]

ES250532A1 - Improvements in or relating to new phenylacetic acid derivatives having central depressant activity and processes for their production - Google Patents

Improvements in or relating to new phenylacetic acid derivatives having central depressant activity and processes for their production

Info

Publication number
ES250532A1
ES250532A1 ES0250532A ES250532A ES250532A1 ES 250532 A1 ES250532 A1 ES 250532A1 ES 0250532 A ES0250532 A ES 0250532A ES 250532 A ES250532 A ES 250532A ES 250532 A1 ES250532 A1 ES 250532A1
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
radical
general formula
atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0250532A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nederlandsche Combinatie voor Chemische Industrie NV
Original Assignee
Nederlandsche Combinatie voor Chemische Industrie NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlandsche Combinatie voor Chemische Industrie NV filed Critical Nederlandsche Combinatie voor Chemische Industrie NV
Publication of ES250532A1 publication Critical patent/ES250532A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention comprises compounds of the general formula <FORM:0893391/IV (b)/1> (wherein R1 and R2 each represent a hydrogen atom, a C1-5 alkyl radical or phenyl radical, R3 represents a hydrogen atom or a C1-5 alkyl radical, R4 represents a hydrogen atom, an alkyl, alkenyl or alkynyl radical of not more than 5 carbon atoms, or a cycloalkyl, aralkyl, aryl or heteroaromatic radical, and Rn represents one or more hydrogen or halogen atoms or C1-5 alkyl or alkoxy radicals), and the preparation thereof by reacting a 2-halopyrazine of the general formula <FORM:0893391/IV (b)/2> (wherein Hal represents a halogen atom) with a phenylacetonitrile alkali metal compound of the general formula <FORM:0893391/IV (b)/3> (wherein Me represents an alkali metal atom), or, when R4 is other than hydrogen, by reacting an alkali metal compound of a compound in which R4 is hydrogen with an alkyl, alkenyl, alkynyl, cycloalkyl, aralkyl, aryl or heteroaromatic halide. Alternatively, a compound of the first general formula above in which R4 represents a halogen atom may be reacted with a suitable alkali or alkaline-earth metal compound (e.g. phenyl lithium or an alkylmagnesium halide). The products have sedative or anticonvulsive activity. Specification 893,392 is referred to.
ES0250532A 1958-07-05 1959-07-04 Improvements in or relating to new phenylacetic acid derivatives having central depressant activity and processes for their production Expired ES250532A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL229365 1958-07-05

Publications (1)

Publication Number Publication Date
ES250532A1 true ES250532A1 (en) 1959-12-16

Family

ID=19751268

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0250532A Expired ES250532A1 (en) 1958-07-05 1959-07-04 Improvements in or relating to new phenylacetic acid derivatives having central depressant activity and processes for their production

Country Status (5)

Country Link
BE (1) BE580400A (en)
CH (1) CH386429A (en)
DE (1) DE1101425B (en)
ES (1) ES250532A1 (en)
GB (2) GB893392A (en)

Also Published As

Publication number Publication date
GB893392A (en) 1962-04-11
DE1101425B (en) 1961-03-09
CH386429A (en) 1965-01-15
GB893391A (en) 1962-04-11
BE580400A (en) 1959-11-03

Similar Documents

Publication Publication Date Title
GB1133766A (en) Novel acetals and a process for the manufacture and conversion thereof
GB1377225A (en) Acylanilino compounds and herbicidal compositions containing them
GB869776A (en) Isobutyrophenone compounds and the production thereof
GB1170930A (en) Processes for the Production of Halogenated Phenoxysilanes
GB1304080A (en)
ES250532A1 (en) Improvements in or relating to new phenylacetic acid derivatives having central depressant activity and processes for their production
GB1340297A (en) Thionophosphoric phosphinic acid esters and their use as insecitcides and acaricides
GB1334814A (en) N-sulphenylated carbamates their manufacture and their use as insecticides acaricides and fungicides
GB1514862A (en) 3-trifluoromethyl-4-aryl-5-amino-pyrazoles
GB901455A (en) C-substituted piperazinones and the manufacture thereof
GB1514709A (en) Fungicidal thioamides
GB1527400A (en) Phosphoric acid amide esters and their use as insecticides acaricides or nematicides
ES346884A1 (en) 0,2,4-oxdiazolidine derivatives, process for their production and herbicidal compositions containing same
GB1326481A (en) P-fluoro-m-trifluoromethylphenylureas their manufacture and pesticidal preparations containing them
GB1447954A (en) Process for the preparation of 1,2,4-triazole derivative
GB970954A (en) Preparation of phenazasilines and intermediates in that preparation
GB1221389A (en) 2,4-dicyano-6-nitrobenzene derivatives
GB1444967A (en) Pyrocatechol ethers
GB1488851A (en) 2-amino-tetralin-1-ones
GB1299053A (en) Substituted 6-nitroaniline derivatives, processes for their preparation, and their use as herbicidal agents
GB1036271A (en) New tertiary aryloxyalkylaminoalkylamines and their manufacture
GB1510367A (en) Isoindoles
GB728368A (en) Improvements in or relating to the production of 3-pyrazolidones
ES273864A1 (en) Novel piperazine derivatives and a process for the manufacture thereof
GB1084287A (en)