[go: up one dir, main page]

ES2198203B1 - Nuevos metodos analiticos basados en la expresion de determinados receptores de celulas nk en celulas t cd8. - Google Patents

Nuevos metodos analiticos basados en la expresion de determinados receptores de celulas nk en celulas t cd8.

Info

Publication number
ES2198203B1
ES2198203B1 ES200200447A ES200200447A ES2198203B1 ES 2198203 B1 ES2198203 B1 ES 2198203B1 ES 200200447 A ES200200447 A ES 200200447A ES 200200447 A ES200200447 A ES 200200447A ES 2198203 B1 ES2198203 B1 ES 2198203B1
Authority
ES
Spain
Prior art keywords
cells
expression
certain
analytical methods
cell receptors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES200200447A
Other languages
English (en)
Other versions
ES2198203A1 (es
Inventor
Rafael Solana Lara
Jose Peña Martinez
Raquel Tarazona Lafarga
Maria Dolores Galiani Ramos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Cordoba
Original Assignee
Universidad de Cordoba
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de Cordoba filed Critical Universidad de Cordoba
Priority to ES200200447A priority Critical patent/ES2198203B1/es
Publication of ES2198203A1 publication Critical patent/ES2198203A1/es
Application granted granted Critical
Publication of ES2198203B1 publication Critical patent/ES2198203B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Nuevos métodos analíticos basados en la expresión de determinados receptores de células NK en células T CD8.
Dichos métodos analíticos se basan esencialmente en la medida del nivel de expresión de determinados receptores de células NK en células T CD8 mediante técnicas de inmunofluorescencia y citometría de flujo.
Estos métodos tienen importantes aplicaciones en medicina para la detección, seguimiento y evolución de enfermedades con repercusiones inmunológicas, especialmente SIDA.
ES200200447A 2002-02-25 2002-02-25 Nuevos metodos analiticos basados en la expresion de determinados receptores de celulas nk en celulas t cd8. Expired - Fee Related ES2198203B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES200200447A ES2198203B1 (es) 2002-02-25 2002-02-25 Nuevos metodos analiticos basados en la expresion de determinados receptores de celulas nk en celulas t cd8.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200200447A ES2198203B1 (es) 2002-02-25 2002-02-25 Nuevos metodos analiticos basados en la expresion de determinados receptores de celulas nk en celulas t cd8.

Publications (2)

Publication Number Publication Date
ES2198203A1 ES2198203A1 (es) 2004-01-16
ES2198203B1 true ES2198203B1 (es) 2005-04-01

Family

ID=30470530

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200200447A Expired - Fee Related ES2198203B1 (es) 2002-02-25 2002-02-25 Nuevos metodos analiticos basados en la expresion de determinados receptores de celulas nk en celulas t cd8.

Country Status (1)

Country Link
ES (1) ES2198203B1 (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5006459A (en) * 1986-03-31 1991-04-09 T Cell Sciences, Inc. Therapeutic and diagnostic methods using soluble T cell surface molecules
ES2051651B1 (es) * 1992-12-10 1995-01-01 Univ Salamanca Procedimiento para la cuantificacion simultanea, en una sola medicion, de los principales tipos de linfocitos humanos y sus subpoblaciones.
JPH11271304A (ja) * 1998-03-24 1999-10-08 Jcr Pharmaceuticals Co Ltd Ｈｉｖ感染の診断方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
AHMAD et al. Modulation of expression of the MHC class I-binding natural killer cell receptors, and NK activity in relation to viral load in HIV-infected/AIDS patients. J. Med. Virol. Noviembre 2001, Vol. 65, Nº 3, páginas 431-40. *
LUCIA B. et al. Evidence of a selective depletion of a CD16+, CD56+, CD8+ natural killer cell subset during HIV infection. Cytometry. Marzo 1995, Vol. 22, Nº 1, páginas 10-15. *
TARAZONA et al. NK-associated receptors on CD8 T cells from treatment-naive HIV-infected individuals: defective expression of CD56. AIDS. Enero 2002, Vol. 16, Nº 2, páginas 197-200. *

Also Published As

Publication number Publication date
ES2198203A1 (es) 2004-01-16

Similar Documents

Publication Publication Date Title
Berner et al. Analysis of Th1 and Th2 cytokines expressing CD4+ and CD8+ T cells in rheumatoid arthritis by flow cytometry.
Romeu et al. Lymphocyte immunophenotyping by flow cytometry in normal adults. Comparison of fresh whole blood lysis technique, Ficoll-Paque separation and cryopreservation.
Nanki et al. Migration of CX3CR1‐positive T cells producing type 1 cytokines and cytotoxic molecules into the synovium of patients with rheumatoid arthritis
Nandula et al. Activation of innate immunity accelerates sialoadenitis in a mouse model for Sjögren’s syndrome‐like disease
Bailer et al. IL-13 and IFN-γ secretion by activated T cells in HIV-1 infection associated with viral suppression and a lack of disease progression
AR095541A1 (es) Muteínas de interleucina-2 (il-2) para la expansión de células t reguladoras
Melis et al. Senescence marker killer cell lectin-like receptor G1 (KLRG1) contributes to TNF-α production by interaction with its soluble E-cadherin ligand in chronically inflamed joints
Kotake et al. Elevated ratio of Th17 cell‐derived Th1 cells (CD161+ Th1 cells) to CD161+ Th17 cells in peripheral blood of early‐onset rheumatoid arthritis patients
Marple et al. Cutting edge: helminth coinfection blocks effector differentiation of CD8 T cells through alternate host Th2-and IL-10–mediated responses
Wu et al. Relationship of CD146 expression to secretion of interleukin (IL)-17, IL-22 and interferon-γ by CD4+ T cells in patients with inflammatory arthritis
ES2198203B1 (es) Nuevos metodos analiticos basados en la expresion de determinados receptores de celulas nk en celulas t cd8.
Curran et al. PHYLOGENETIC AFFINITIES OF PLAGIOCIRRUS WITH THE DESCRIPTION OF A NEW SPECIES FROM THE PASCAGOULA RIVER, MISSISSIPPI
Matsuki et al. CD45RA− Foxp3low non-regulatory T cells in the CCR7− CD45RA− CD27+ CD28+ effector memory subset are increased in synovial fluid from patients with rheumatoid arthritis
Miao et al. Percentages of CD4+ CD161+ and CD4− CD8− CD161+ T Cells in the Synovial Fluid Are Correlated with Disease Activity in Rheumatoid Arthritis
Zhou et al. CD3+ CD56+ natural killer T cell activity in children with different forms of juvenile idiopathic arthritis and the influence of etanercept treatment on polyarticular subgroup
Amosova et al. Proinflammatory cytokine levels in patients with diastolic heart failure
Al-Taiy et al. Relationship of Cytokines Concentration With Mastitis Infection Degree in Holstein Cows Reared in The Middle of Iraq
Osman The Role of Interferon and Non-conventional T-cells in the Clearance of Primary Bhv-1 Respiratory Infection
松山敏之 IL-8 produced by T cells is under the control of dopamine signaling
Ahmad et al. Effects of Gold Nanoparticles and Etanercept on the Expression of TNFR2 Expressing Regulatory T cells and CD103+ Dendritic Cells on Human PBMC in Asthmatic Individuals
Ataei et al. Development of a Microfluidic Device to Sort Sperm based on their Swimming Potential against the Flow
Chatenoud Treatment of autoimmune disease: Biological and molecular therapies
Polkinghorne et al. Overview of Meat Standards Australia (MSA) and cuts based grading schemes
Cheng et al. Expression levels of complement regulatory proteins CD55 and CD59 in the peripheral blood of patients with Stevens-Johnson syndrome/toxic epidermal necrolysis
CHEN et al. Mir-219-5p Alleviates Spinal Cord Injury in PC12 Cells Induced by Lipopolysaccharide by Targeting KLF4

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 20040116

Kind code of ref document: A1

FG2A Definitive protection

Ref document number: 2198203B1

Country of ref document: ES

FD2A Announcement of lapse in spain

Effective date: 20220601