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ES2194139T3 - Aumento de la sensibilidad en la determinacion inmunoquimica de un analito. - Google Patents

Aumento de la sensibilidad en la determinacion inmunoquimica de un analito.

Info

Publication number
ES2194139T3
ES2194139T3 ES97110263T ES97110263T ES2194139T3 ES 2194139 T3 ES2194139 T3 ES 2194139T3 ES 97110263 T ES97110263 T ES 97110263T ES 97110263 T ES97110263 T ES 97110263T ES 2194139 T3 ES2194139 T3 ES 2194139T3
Authority
ES
Spain
Prior art keywords
analyte
solid phase
binding
sensitivity
increase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97110263T
Other languages
English (en)
Inventor
Stefan Dr Brust
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Dade Behring Marburg GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Behring Marburg GmbH filed Critical Dade Behring Marburg GmbH
Application granted granted Critical
Publication of ES2194139T3 publication Critical patent/ES2194139T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/974—Aids related test
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN PROCEDIMIENTO PARA LA DETERMINACION DE UN ANALITO, DONDE UNA DE LAS MUESTRAS QUE EVENTUALMENTE CONTIENE LOS ANALITOS A DETERMINAR SE PONE EN CONTACTO CON UN PRIMER RECEPTOR R1 INMOVILIZADO SOBRE UNA FASE SOLIDA, EL CUAL TIENE UNA AFINIDAD DE UNION CON EL ANALITO Y AÑADIENDO UN RECEPTOR R2, QUE EVENTUALMENTE TIENE UNA AFINIDAD DE UNION CON EL ANALITO Y DONDE ADEMAS SE PONEN EN CONTACTO LOS COMPLEJOS INMUNOLOGICOS ORIGINADOS CON UN FACTOR DE UNION, QUE TIENE UNA AFINIDAD DE UNION CON EL ANALITO Y CON UN RECEPTOR R3 INMOVILIZADO SOBRE LA MISMA FASE O SOBRE UNA SEGUNDA FASE Y DONDE LA CANTIDAD DEL ANALITO UNIDO A LA PRIMERA FASE SOLIDA O, EN CASO DE QUE EXISTA, A LA SEGUNDA FASE SOLIDA, SE DETECTA DE FORMA APROPIADA.
ES97110263T 1996-07-22 1997-06-24 Aumento de la sensibilidad en la determinacion inmunoquimica de un analito. Expired - Lifetime ES2194139T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19629444A DE19629444A1 (de) 1996-07-22 1996-07-22 Sensitivitätssteigerung bei der immunchemischen Bestimmung eines Analyten

Publications (1)

Publication Number Publication Date
ES2194139T3 true ES2194139T3 (es) 2003-11-16

Family

ID=7800445

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97110263T Expired - Lifetime ES2194139T3 (es) 1996-07-22 1997-06-24 Aumento de la sensibilidad en la determinacion inmunoquimica de un analito.

Country Status (8)

Country Link
US (1) US6030770A (es)
EP (1) EP0825441B1 (es)
JP (1) JPH1078435A (es)
AT (1) ATE235684T1 (es)
AU (1) AU2875097A (es)
CA (1) CA2210916A1 (es)
DE (2) DE19629444A1 (es)
ES (1) ES2194139T3 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6699722B2 (en) 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
US7262019B2 (en) * 2001-05-03 2007-08-28 Immunetics, Inc. System and methods for detection of Bacillus anthracis related analytes in biological fluids
US7105311B2 (en) * 2001-05-03 2006-09-12 Immunetics, Inc. Systems and methods for detection of analytes in biological fluids
US7387890B2 (en) * 2004-12-16 2008-06-17 Chembio Diagnostic Systems, Inc. Immunoassay devices and use thereof
US7396689B2 (en) * 2005-02-04 2008-07-08 Decision Biomarkers Incorporated Method of adjusting the working range of a multi-analyte assay
CA2793959C (en) 2010-03-25 2019-06-04 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
PT2691530T (pt) 2011-06-10 2018-05-10 Univ Oregon Health & Science Glicoproteínas e vectores recombinantes cmv
AU2012216792A1 (en) 2011-09-12 2013-03-28 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
EP2873423B1 (en) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3072901A1 (en) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
CN111902720B (zh) 2018-03-21 2025-02-07 沃特世科技公司 基于非抗体高亲和力的样品制备、吸附剂、装置和方法
CN113125704A (zh) * 2019-12-31 2021-07-16 科美诊断技术股份有限公司 一种均相化学发光测定试剂盒及其应用
CN113125697B (zh) * 2019-12-31 2024-03-26 科美博阳诊断技术(上海)有限公司 一种睾酮均相化学发光检测试剂盒及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4228237A (en) * 1978-09-21 1980-10-14 Calbiochem-Behring Corp. Methods for the detection and determination of ligands
US4495296A (en) * 1979-05-21 1985-01-22 New York Blood Center, Inc. Labeled anti-hapten antibodies and their use as a universal reagent for solid phase radio- and/or enzyme-immunoassays
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4743542A (en) * 1985-04-11 1988-05-10 Ortho Diagnostic Method for forestalling the hook effect in a multi-ligand immunoassay system
US5312730A (en) * 1992-05-27 1994-05-17 Ciba Corning Diagnostics Corp. Immune complex transfer with lypophilic bridge
DE4218257A1 (de) * 1992-06-03 1993-12-09 Behringwerke Ag Verfahren zur immunchemischen Bestimmung eines Analyten

Also Published As

Publication number Publication date
DE59709605D1 (de) 2003-04-30
ATE235684T1 (de) 2003-04-15
EP0825441B1 (de) 2003-03-26
DE19629444A1 (de) 1998-01-29
US6030770A (en) 2000-02-29
EP0825441A1 (de) 1998-02-25
JPH1078435A (ja) 1998-03-24
AU2875097A (en) 1998-01-29
CA2210916A1 (en) 1998-01-22

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