ES2189163T3 - Nitro-benzamidas utiles como agentes anti-arritmicos. - Google Patents
Nitro-benzamidas utiles como agentes anti-arritmicos.Info
- Publication number
- ES2189163T3 ES2189163T3 ES98920498T ES98920498T ES2189163T3 ES 2189163 T3 ES2189163 T3 ES 2189163T3 ES 98920498 T ES98920498 T ES 98920498T ES 98920498 T ES98920498 T ES 98920498T ES 2189163 T3 ES2189163 T3 ES 2189163T3
- Authority
- ES
- Spain
- Prior art keywords
- provides
- nitro
- benzamidas
- arritmic
- agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Hidrocloruro hidratado de N-{[}3-{[}{[}2-{(}3,4- dimetoxifenil{etil]amino{]}propil{]}-4-nitro benzamida que se caracteriza porque: (i) comprende agua en el intervalo entre 1,7 a 2,4equivalentes molares; y/o (ii) tiene un punto de fusión por encima de 145ºC y/o (iii) proporciona un espectro infrarrojo que contiene picos a 3510, 3342, 3076, 1665, 1598, 1343, 1330, 1216 y 801 cm{sup,-1}; y/o (iv) proporciona un espectro de resonancia magnética nuclear en estado sólido que contiene desplazamientos químicos tal y como se representa en la Tabla I; y/o (v) proporciona una configuración de refracción de polvo de rayos X (XRPD) tal y como se representa en la Tabla II; un procedimiento de preparación de dicho compuesto, una composición farmacéutica que lo comprende y la utilización de dicho compuesto en medicina.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9706376.2A GB9706376D0 (en) | 1997-03-27 | 1997-03-27 | Novel pharmaceutical |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2189163T3 true ES2189163T3 (es) | 2003-07-01 |
Family
ID=10809958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98920498T Expired - Lifetime ES2189163T3 (es) | 1997-03-27 | 1998-03-24 | Nitro-benzamidas utiles como agentes anti-arritmicos. |
Country Status (37)
| Country | Link |
|---|---|
| US (1) | US20040092771A1 (es) |
| EP (1) | EP0971882B1 (es) |
| JP (1) | JP2001518088A (es) |
| KR (1) | KR20010005566A (es) |
| CN (1) | CN1257478A (es) |
| AP (1) | AP1205A (es) |
| AT (1) | ATE228997T1 (es) |
| AU (1) | AU741476B2 (es) |
| BG (1) | BG103829A (es) |
| BR (1) | BR9809054A (es) |
| CA (1) | CA2285197A1 (es) |
| DE (1) | DE69809891T2 (es) |
| DK (1) | DK0971882T3 (es) |
| DZ (1) | DZ2452A1 (es) |
| EA (1) | EA002439B1 (es) |
| EG (1) | EG21226A (es) |
| ES (1) | ES2189163T3 (es) |
| GB (1) | GB9706376D0 (es) |
| HK (1) | HK1025089A1 (es) |
| HU (1) | HUP0001683A3 (es) |
| ID (1) | ID22787A (es) |
| IL (1) | IL132042A0 (es) |
| IN (1) | IN188180B (es) |
| MA (1) | MA26477A1 (es) |
| NO (1) | NO994682L (es) |
| NZ (1) | NZ337794A (es) |
| OA (1) | OA11200A (es) |
| PE (1) | PE61799A1 (es) |
| PL (1) | PL335879A1 (es) |
| PT (1) | PT971882E (es) |
| SK (1) | SK283056B6 (es) |
| TR (1) | TR199902356T2 (es) |
| TW (1) | TW518318B (es) |
| UA (1) | UA57066C2 (es) |
| UY (1) | UY24937A1 (es) |
| WO (1) | WO1998043947A1 (es) |
| ZA (1) | ZA982558B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9923934D0 (en) * | 1999-10-08 | 1999-12-08 | Smithkline Beecham Plc | Novel pharmaceutical |
| GB9923933D0 (en) * | 1999-10-08 | 1999-12-08 | Smithkline Beecham Lab | Novel pharmaceutical |
| US8483008B2 (en) * | 2008-11-08 | 2013-07-09 | Westerngeco L.L.C. | Coil shooting mode |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2726267B1 (fr) * | 1994-10-26 | 1998-01-02 | Smithkline Beecham Lab | Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer |
-
1997
- 1997-03-27 GB GBGB9706376.2A patent/GB9706376D0/en active Pending
-
1998
- 1998-03-24 HU HU0001683A patent/HUP0001683A3/hu unknown
- 1998-03-24 DE DE69809891T patent/DE69809891T2/de not_active Expired - Fee Related
- 1998-03-24 CN CN98805301A patent/CN1257478A/zh active Pending
- 1998-03-24 KR KR1019997008629A patent/KR20010005566A/ko not_active Application Discontinuation
- 1998-03-24 AT AT98920498T patent/ATE228997T1/de not_active IP Right Cessation
- 1998-03-24 ES ES98920498T patent/ES2189163T3/es not_active Expired - Lifetime
- 1998-03-24 AP APAP/P/1999/001651A patent/AP1205A/en active
- 1998-03-24 JP JP54116698A patent/JP2001518088A/ja not_active Ceased
- 1998-03-24 CA CA002285197A patent/CA2285197A1/en not_active Abandoned
- 1998-03-24 ID IDW991093A patent/ID22787A/id unknown
- 1998-03-24 SK SK1302-99A patent/SK283056B6/sk unknown
- 1998-03-24 NZ NZ337794A patent/NZ337794A/en unknown
- 1998-03-24 EP EP98920498A patent/EP0971882B1/en not_active Expired - Lifetime
- 1998-03-24 BR BR9809054-2A patent/BR9809054A/pt not_active IP Right Cessation
- 1998-03-24 PL PL98335879A patent/PL335879A1/xx unknown
- 1998-03-24 TR TR1999/02356T patent/TR199902356T2/xx unknown
- 1998-03-24 WO PCT/EP1998/001913 patent/WO1998043947A1/en not_active Application Discontinuation
- 1998-03-24 PT PT98920498T patent/PT971882E/pt unknown
- 1998-03-24 EA EA199900879A patent/EA002439B1/ru not_active IP Right Cessation
- 1998-03-24 IL IL13204298A patent/IL132042A0/xx unknown
- 1998-03-24 DK DK98920498T patent/DK0971882T3/da active
- 1998-03-24 UA UA99095241A patent/UA57066C2/uk unknown
- 1998-03-24 AU AU73341/98A patent/AU741476B2/en not_active Ceased
- 1998-03-25 MA MA25011A patent/MA26477A1/fr unknown
- 1998-03-25 DZ DZ980062A patent/DZ2452A1/xx active
- 1998-03-25 PE PE1998000218A patent/PE61799A1/es not_active Application Discontinuation
- 1998-03-26 EG EG34498A patent/EG21226A/xx active
- 1998-03-26 ZA ZA9802558A patent/ZA982558B/xx unknown
- 1998-03-26 IN IN786DE1998 patent/IN188180B/en unknown
- 1998-03-26 UY UY24937A patent/UY24937A1/es unknown
- 1998-04-01 TW TW087104862A patent/TW518318B/zh not_active IP Right Cessation
-
1999
- 1999-09-24 NO NO994682A patent/NO994682L/no not_active Application Discontinuation
- 1999-09-27 OA OA9900218A patent/OA11200A/en unknown
- 1999-10-22 BG BG103829A patent/BG103829A/bg unknown
-
2000
- 2000-07-17 HK HK00104363A patent/HK1025089A1/xx not_active IP Right Cessation
-
2003
- 2003-12-02 US US10/725,893 patent/US20040092771A1/en not_active Abandoned
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