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ES2182161T3 - Utilizacion de derivados de pirimidina para la preparacion de un medicamento para la prevencion del cancer. - Google Patents

Utilizacion de derivados de pirimidina para la preparacion de un medicamento para la prevencion del cancer.

Info

Publication number
ES2182161T3
ES2182161T3 ES98103410T ES98103410T ES2182161T3 ES 2182161 T3 ES2182161 T3 ES 2182161T3 ES 98103410 T ES98103410 T ES 98103410T ES 98103410 T ES98103410 T ES 98103410T ES 2182161 T3 ES2182161 T3 ES 2182161T3
Authority
ES
Spain
Prior art keywords
cancer
prevention
preparation
medicinal product
pirimidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98103410T
Other languages
English (en)
Inventor
Karl Dr Geisen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2182161T3 publication Critical patent/ES2182161T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE AL USO DE DERIVADOS DE PIRIMIDINA COMO AGENTE PARA PREVENIR LAS ENFERMEDADES CANCEROSAS. EN LOS DERIVADOS DE PIRIMIDINA UTILIZADOS SE TRATA DE SUSTANCIAS ACTIVAS DE FORMULA I, EN LA QUE R 1 A R 7 TIEN EN EL SIGNIFICADO CITADO, ASI COMO SUS SALES FISIOLOGICAMENTE ACEPTABLES.
ES98103410T 1997-03-13 1998-02-27 Utilizacion de derivados de pirimidina para la preparacion de un medicamento para la prevencion del cancer. Expired - Lifetime ES2182161T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19710435A DE19710435A1 (de) 1997-03-13 1997-03-13 Verwendung von Pyrimidinderivaten zur Prävention von Krebs allein oder in Kombination mit anderen therapeutischen Maßnahmen

Publications (1)

Publication Number Publication Date
ES2182161T3 true ES2182161T3 (es) 2003-03-01

Family

ID=7823277

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98103410T Expired - Lifetime ES2182161T3 (es) 1997-03-13 1998-02-27 Utilizacion de derivados de pirimidina para la preparacion de un medicamento para la prevencion del cancer.

Country Status (19)

Country Link
US (1) US6156755A (es)
EP (1) EP0864327B1 (es)
JP (1) JPH10279482A (es)
KR (1) KR19980080148A (es)
CN (1) CN1193513A (es)
AR (1) AR011190A1 (es)
AT (1) ATE227129T1 (es)
AU (1) AU726089B2 (es)
BR (1) BR9800884A (es)
CA (1) CA2231765A1 (es)
CZ (1) CZ74698A3 (es)
DE (2) DE19710435A1 (es)
DK (1) DK0864327T3 (es)
ES (1) ES2182161T3 (es)
HU (1) HUP9800535A1 (es)
PL (1) PL325327A1 (es)
PT (1) PT864327E (es)
RU (1) RU2209629C2 (es)
TR (1) TR199800436A2 (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012485A1 (en) 1998-08-29 2000-03-09 Astrazeneca Ab Pyrimidine compounds
ATE336484T1 (de) 1998-08-29 2006-09-15 Astrazeneca Ab Pyrimidine verbindungen
GB9828511D0 (en) 1998-12-24 1999-02-17 Zeneca Ltd Chemical compounds
GB9905075D0 (en) 1999-03-06 1999-04-28 Zeneca Ltd Chemical compounds
GB9907658D0 (en) 1999-04-06 1999-05-26 Zeneca Ltd Chemical compounds
GB9919778D0 (en) 1999-08-21 1999-10-27 Zeneca Ltd Chemical compounds
GB0004890D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0004887D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0004888D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0004886D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0007371D0 (en) 2000-03-28 2000-05-17 Astrazeneca Uk Ltd Chemical compounds
GB0016877D0 (en) 2000-07-11 2000-08-30 Astrazeneca Ab Chemical compounds
GB0021726D0 (en) 2000-09-05 2000-10-18 Astrazeneca Ab Chemical compounds
US6716851B2 (en) 2000-12-12 2004-04-06 Cytovia, Inc. Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators or caspases and inducers of apoptosis and the use thereof
WO2002059111A2 (en) * 2000-12-21 2002-08-01 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
GB0103926D0 (en) 2001-02-17 2001-04-04 Astrazeneca Ab Chemical compounds
GB0113041D0 (en) 2001-05-30 2001-07-18 Astrazeneca Ab Chemical compounds
US6825198B2 (en) * 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
TWI330183B (es) * 2001-10-22 2010-09-11 Eisai R&D Man Co Ltd
US7442697B2 (en) 2002-03-09 2008-10-28 Astrazeneca Ab 4-imidazolyl substituted pyrimidine derivatives with CDK inhibitory activity
GB0205688D0 (en) 2002-03-09 2002-04-24 Astrazeneca Ab Chemical compounds
GB0205693D0 (en) 2002-03-09 2002-04-24 Astrazeneca Ab Chemical compounds
GB0205690D0 (en) 2002-03-09 2002-04-24 Astrazeneca Ab Chemical compounds
RU2491071C2 (ru) * 2002-07-29 2013-08-27 Райджел Фармасьютикалз, Инк. Способы лечения или профилактики аутоиммунных заболеваний с помощью соединений 2,4-пиримидиндиамина
JP2006514989A (ja) * 2002-07-29 2006-05-18 ライジェル ファーマシューティカルズ ２，４−ピリミジンジアミン化合物による自己免疫疾患の治療および予防方法
GB0311274D0 (en) 2003-05-16 2003-06-18 Astrazeneca Ab Chemical compounds
GB0311276D0 (en) 2003-05-16 2003-06-18 Astrazeneca Ab Chemical compounds
GB0323137D0 (en) * 2003-10-03 2003-11-05 Chang Lisa C W 2,4,6- Trisubstituted pyrimidines and their different uses
UA83101C2 (en) * 2003-12-15 2008-06-10 Алмирал Аг 2,6-bisheteroaryl-4-aminopyrimidines as adenosine receptor antagonists
TW200528101A (en) 2004-02-03 2005-09-01 Astrazeneca Ab Chemical compounds
DE602006020864D1 (de) * 2005-04-11 2011-05-05 Almirall Sa 2, 6-di-(hetero-)aryl-4-amido-pyrimidine als adenosin-rezeptor-antagonisten
US20060293343A1 (en) * 2005-05-18 2006-12-28 Asahi Kasei Pharma Corporation Pyrimidine derivatives
US7745428B2 (en) 2005-09-30 2010-06-29 Astrazeneca Ab Imidazo[1,2-A]pyridine having anti-cell-proliferation activity
EP2121662A1 (en) * 2006-12-04 2009-11-25 Neurocrine Biosciences, Inc. Substituted pyrimidines as adenosine receptor antagonists
WO2008116185A2 (en) * 2007-03-21 2008-09-25 Neurocrine Biosciences, Inc. Substituted pyrimidines as adenosine receptor antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB884772A (en) * 1958-01-16 1961-12-20 Merck & Co Inc 2-alkoxy-4-amino pyrimidines
DE3905364A1 (de) * 1989-02-22 1990-08-23 Hoechst Ag Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool
DE4025387A1 (de) * 1990-08-10 1992-02-13 Hoechst Ag Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als reagenzien
NZ254550A (en) * 1992-09-28 1997-08-22 Pfizer Use of nitrogen-substituted pyrimidines to prepare medicaments useful for treatment or prevention of diabetic complications

Also Published As

Publication number Publication date
PT864327E (pt) 2003-03-31
EP0864327A1 (de) 1998-09-16
KR19980080148A (ko) 1998-11-25
PL325327A1 (en) 1998-09-14
DE59806139D1 (de) 2002-12-12
TR199800436A3 (tr) 1998-10-21
EP0864327B1 (de) 2002-11-06
CN1193513A (zh) 1998-09-23
AU726089B2 (en) 2000-11-02
HUP9800535A1 (hu) 2000-11-28
JPH10279482A (ja) 1998-10-20
BR9800884A (pt) 1999-12-07
AR011190A1 (es) 2000-08-02
ATE227129T1 (de) 2002-11-15
DK0864327T3 (da) 2003-02-17
AU5835098A (en) 1998-09-17
DE19710435A1 (de) 1998-09-17
RU2209629C2 (ru) 2003-08-10
TR199800436A2 (xx) 1998-10-21
HU9800535D0 (en) 1998-04-28
CA2231765A1 (en) 1998-09-13
US6156755A (en) 2000-12-05
CZ74698A3 (cs) 1998-09-16

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