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BR9800884A - Aplicação de derivados de pirimidina para a prevenção do câncer, por si só ou em combinação com outras medidas terapêuticas. - Google Patents

Aplicação de derivados de pirimidina para a prevenção do câncer, por si só ou em combinação com outras medidas terapêuticas.

Info

Publication number
BR9800884A
BR9800884A BR9800884-6A BR9800884A BR9800884A BR 9800884 A BR9800884 A BR 9800884A BR 9800884 A BR9800884 A BR 9800884A BR 9800884 A BR9800884 A BR 9800884A
Authority
BR
Brazil
Prior art keywords
pyrimidine derivatives
application
combination
alone
therapeutic measures
Prior art date
Application number
BR9800884-6A
Other languages
English (en)
Inventor
Karl Dr Geisen
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of BR9800884A publication Critical patent/BR9800884A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção:<B>"APLICAçãO DE DERIVADOS DE PIRIMIDINA PARA A PREVENçãO DO CâNCER, POR SI Só OU EM COMBINAçãO COM OUTRAS MEDIDAS TERAPêUTICAS"<D>. A presente invenção está ligada com a aplicação de derivados de pirimidina como agentes para a prevenção de distúrbios carcinomatosos. Os derivados de pirimidina aplicados são compostos ativos da fórmula I na quel R^ 1^ até R^ 7^ têm o significado mencionado e seus sais toleráveis fisilogicamente.
BR9800884-6A 1997-03-13 1998-03-12 Aplicação de derivados de pirimidina para a prevenção do câncer, por si só ou em combinação com outras medidas terapêuticas. BR9800884A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19710435A DE19710435A1 (de) 1997-03-13 1997-03-13 Verwendung von Pyrimidinderivaten zur Prävention von Krebs allein oder in Kombination mit anderen therapeutischen Maßnahmen

Publications (1)

Publication Number Publication Date
BR9800884A true BR9800884A (pt) 1999-12-07

Family

ID=7823277

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9800884-6A BR9800884A (pt) 1997-03-13 1998-03-12 Aplicação de derivados de pirimidina para a prevenção do câncer, por si só ou em combinação com outras medidas terapêuticas.

Country Status (19)

Country Link
US (1) US6156755A (pt)
EP (1) EP0864327B1 (pt)
JP (1) JPH10279482A (pt)
KR (1) KR19980080148A (pt)
CN (1) CN1193513A (pt)
AR (1) AR011190A1 (pt)
AT (1) ATE227129T1 (pt)
AU (1) AU726089B2 (pt)
BR (1) BR9800884A (pt)
CA (1) CA2231765A1 (pt)
CZ (1) CZ74698A3 (pt)
DE (2) DE19710435A1 (pt)
DK (1) DK0864327T3 (pt)
ES (1) ES2182161T3 (pt)
HU (1) HUP9800535A1 (pt)
PL (1) PL325327A1 (pt)
PT (1) PT864327E (pt)
RU (1) RU2209629C2 (pt)
TR (1) TR199800436A2 (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5438499A (en) 1998-08-29 2000-03-21 Astrazeneca Ab Pyrimidine compounds
WO2000012485A1 (en) 1998-08-29 2000-03-09 Astrazeneca Ab Pyrimidine compounds
GB9828511D0 (en) 1998-12-24 1999-02-17 Zeneca Ltd Chemical compounds
GB9905075D0 (en) 1999-03-06 1999-04-28 Zeneca Ltd Chemical compounds
GB9907658D0 (en) 1999-04-06 1999-05-26 Zeneca Ltd Chemical compounds
GB9919778D0 (en) 1999-08-21 1999-10-27 Zeneca Ltd Chemical compounds
GB0004888D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0004887D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0004890D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0004886D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0007371D0 (en) 2000-03-28 2000-05-17 Astrazeneca Uk Ltd Chemical compounds
GB0016877D0 (en) 2000-07-11 2000-08-30 Astrazeneca Ab Chemical compounds
GB0021726D0 (en) 2000-09-05 2000-10-18 Astrazeneca Ab Chemical compounds
US6716851B2 (en) * 2000-12-12 2004-04-06 Cytovia, Inc. Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators or caspases and inducers of apoptosis and the use thereof
GB0103926D0 (en) 2001-02-17 2001-04-04 Astrazeneca Ab Chemical compounds
GB0113041D0 (en) 2001-05-30 2001-07-18 Astrazeneca Ab Chemical compounds
US6825198B2 (en) * 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
GB0205688D0 (en) 2002-03-09 2002-04-24 Astrazeneca Ab Chemical compounds
GB0205693D0 (en) 2002-03-09 2002-04-24 Astrazeneca Ab Chemical compounds
GB0205690D0 (en) 2002-03-09 2002-04-24 Astrazeneca Ab Chemical compounds
WO2003076434A1 (en) 2002-03-09 2003-09-18 Astrazeneca Ab 4- imidazolyl substuited pyrimidine derivatives with cdk inhibitiory activity
RU2376992C2 (ru) * 2002-07-29 2009-12-27 Райджел Фармасьютикалз, Инк. Способы лечения или профилактики аутоиммунных заболеваний с помощью соединений 2,4-пиримидиндиамина
AU2003265336B8 (en) * 2002-07-29 2009-04-23 Rigel Pharmaceuticals, Inc. Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
GB0311274D0 (en) 2003-05-16 2003-06-18 Astrazeneca Ab Chemical compounds
GB0311276D0 (en) 2003-05-16 2003-06-18 Astrazeneca Ab Chemical compounds
GB0323137D0 (en) * 2003-10-03 2003-11-05 Chang Lisa C W 2,4,6- Trisubstituted pyrimidines and their different uses
MXPA06006776A (es) * 2003-12-15 2007-03-23 Almirall Prodesfarma Ag 2,6-bisheteroaril-4-aminopirimidinas como antagonistas del receptor de adenosina.
TW200528101A (en) 2004-02-03 2005-09-01 Astrazeneca Ab Chemical compounds
EP1888565B1 (en) * 2005-04-11 2011-03-23 Almirall, S.A. 2, 6-di (hetero) aryl -4-amido-pyrimidines as adenosine receptor antagonists
US20060293343A1 (en) * 2005-05-18 2006-12-28 Asahi Kasei Pharma Corporation Pyrimidine derivatives
CA2623374A1 (en) 2005-09-30 2007-04-05 Astrazeneca Ab Imidazo [1,2-a] pyridine having anti-cell-proliferation activity
CN101679371A (zh) * 2006-12-04 2010-03-24 艾美罗股份公司 作为腺苷受体拮抗剂的取代的嘧啶
EP2132197A2 (en) * 2007-03-21 2009-12-16 Almirall, S.A. Substituted pyrimidines as adenosine receptor antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3905364A1 (de) * 1989-02-22 1990-08-23 Hoechst Ag Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool
DE4025387A1 (de) * 1990-08-10 1992-02-13 Hoechst Ag Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als reagenzien
CA2145640C (en) * 1992-09-28 2001-01-30 Banavara L. Mylari Substituted pyrimidines for control of diabetic complications

Also Published As

Publication number Publication date
CA2231765A1 (en) 1998-09-13
PL325327A1 (en) 1998-09-14
CN1193513A (zh) 1998-09-23
EP0864327A1 (de) 1998-09-16
RU2209629C2 (ru) 2003-08-10
ES2182161T3 (es) 2003-03-01
AU726089B2 (en) 2000-11-02
AU5835098A (en) 1998-09-17
HUP9800535A1 (hu) 2000-11-28
CZ74698A3 (cs) 1998-09-16
ATE227129T1 (de) 2002-11-15
KR19980080148A (ko) 1998-11-25
TR199800436A3 (tr) 1998-10-21
DE19710435A1 (de) 1998-09-17
AR011190A1 (es) 2000-08-02
EP0864327B1 (de) 2002-11-06
US6156755A (en) 2000-12-05
PT864327E (pt) 2003-03-31
DE59806139D1 (de) 2002-12-12
TR199800436A2 (xx) 1998-10-21
HU9800535D0 (en) 1998-04-28
DK0864327T3 (da) 2003-02-17
JPH10279482A (ja) 1998-10-20

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A , 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1912 DE 28/08/2007.