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ES2176329T3 - Procedimientos para preparar formas anhidras e hidratadas de derivados antihistaminicos de piperidina, sus polimeros y pseudomorfos. - Google Patents

Procedimientos para preparar formas anhidras e hidratadas de derivados antihistaminicos de piperidina, sus polimeros y pseudomorfos.

Info

Publication number
ES2176329T3
ES2176329T3 ES95918278T ES95918278T ES2176329T3 ES 2176329 T3 ES2176329 T3 ES 2176329T3 ES 95918278 T ES95918278 T ES 95918278T ES 95918278 T ES95918278 T ES 95918278T ES 2176329 T3 ES2176329 T3 ES 2176329T3
Authority
ES
Spain
Prior art keywords
antihistaminic
anhydrate
piperidine
derivatives
pseudomorphes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95918278T
Other languages
English (en)
Inventor
Daniel R Henton
Frederick J Mccarty
Susan I Tripp
Jill E Dewitt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Aventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26937420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2176329(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharmaceuticals Inc filed Critical Aventis Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2176329T3 publication Critical patent/ES2176329T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Peptides Or Proteins (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A NUEVOS PROCESOS PARA PREPARAR FORMAS ANHIDRAS E HIDRATOS DE DERIVADOS DE PIPERIDINA, POLIMORFOS Y PSUDOMORFOS DE LOS MISMOS DE FORMULAS (I) Y (II) QUE SON UTILES COMO ANTIHISTAMINICOS, AGENTES ANTIALERGICOS Y BRONCODILATADORES.
ES95918278T 1994-05-18 1995-04-28 Procedimientos para preparar formas anhidras e hidratadas de derivados antihistaminicos de piperidina, sus polimeros y pseudomorfos. Expired - Lifetime ES2176329T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24573194A 1994-05-18 1994-05-18
US41716195A 1995-04-11 1995-04-11

Publications (1)

Publication Number Publication Date
ES2176329T3 true ES2176329T3 (es) 2002-12-01

Family

ID=26937420

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95918278T Expired - Lifetime ES2176329T3 (es) 1994-05-18 1995-04-28 Procedimientos para preparar formas anhidras e hidratadas de derivados antihistaminicos de piperidina, sus polimeros y pseudomorfos.

Country Status (18)

Country Link
US (12) US20010025106A1 (es)
EP (3) EP0766668B1 (es)
JP (7) JPH10500134A (es)
CN (3) CN1623985A (es)
AT (1) ATE220667T1 (es)
AU (1) AU693892B2 (es)
CA (3) CA2189007C (es)
DE (1) DE69527429T2 (es)
DK (1) DK0766668T3 (es)
ES (1) ES2176329T3 (es)
FI (1) FI964565A0 (es)
HK (2) HK1098467A1 (es)
HU (1) HU227676B1 (es)
IL (3) IL134917A (es)
MX (1) MX9605613A (es)
NO (1) NO315319B1 (es)
PT (1) PT766668E (es)
WO (1) WO1995031437A1 (es)

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WO1996026726A1 (en) * 1995-02-28 1996-09-06 Hoechst Marion Roussel, Inc. Pharmaceutical composition for piperidinoalkanol compounds
UA60335C2 (uk) * 1997-08-26 2003-10-15 Хехст Маріон Рассел, Інк. Фармацевтична композиція, яка об'єднує піперидиноалканол з протинабряковим агентом
IN191492B (es) * 1999-05-25 2003-12-06 Ranbaxy Lab Ltd
US6613906B1 (en) * 2000-06-06 2003-09-02 Geneva Pharmaceuticals, Inc. Crystal modification
CH695216A5 (de) 2001-02-23 2006-01-31 Cilag Ag Verfahren zur Herstellung eines nicht hydratisierten Salzes eines Piperidinderivats und eine so erhältliche neue kristalline Form eines solchen Salzes.
SK13822003A3 (sk) * 2001-04-09 2004-09-08 Teva Pharmaceutical Industries Ltd. Polymorfné formy chloridu fexofenadínu
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
KR20040015734A (ko) 2001-06-18 2004-02-19 닥터 레디스 레보러터리즈 리미티드 4-[4-[4-(히드록실디페닐메틸)-1-피페리디닐]-1-히드록시부틸]-α,α-디메틸벤젠 아세트산 및 그 염산염의 신규 결정형태
US7700779B2 (en) 2001-06-18 2010-04-20 Dr. Reddy's Laboratories Limited Crystalline forms of fexofenadine and its hydrochloride
DE60225694T2 (de) * 2001-07-31 2008-06-26 Texcontor Etablissement Neues polymorph von fexo-fenadin
US20030158227A1 (en) * 2001-11-08 2003-08-21 Barnaba Krochmal Polymorphs of fexofenadine base
US20040044038A1 (en) * 2002-06-10 2004-03-04 Barnaba Krochmal Polymorphic form XVI of fexofenadine hydrochloride
JP3910907B2 (ja) * 2002-10-29 2007-04-25 新光電気工業株式会社 キャパシタ素子及びこの製造方法、半導体装置用基板、並びに半導体装置
US20050054616A1 (en) * 2003-07-03 2005-03-10 Judith Aronhime Zoledronic acid crystal forms, zoledronate sodium salt crystal forms, amorphous zoledronate sodium salt, and processes for their preparation
GB0319935D0 (en) * 2003-08-26 2003-09-24 Cipla Ltd Polymorphs
EP1628959A2 (en) * 2004-04-26 2006-03-01 Teva Pharmaceutical Industries Ltd Crystalline forms of fexofenadine hydrochloride and processes for their preparation
ITMI20041143A1 (it) 2004-06-08 2004-09-08 Dipharma Spa Polimorfi di fexofenadina e procedimento per la loro preparazione
EP1616861A3 (en) * 2004-06-15 2006-02-08 Dipharma S.p.A. A process for the preparation of keto compounds
ITMI20041568A1 (it) * 2004-07-30 2004-10-30 Dipharma Spa "polimorfi di fexofenadina base"
JP2008514641A (ja) * 2004-09-28 2008-05-08 テバ ファーマシューティカル インダストリーズ リミティド 結晶形フェキソフェナジン、およびその調製方法
DOP2006000274A (es) * 2005-12-14 2007-10-15 Sanofi Aventis Us Llc Formulación de suspensión de fexofenadina
KR20090037930A (ko) * 2006-07-11 2009-04-16 뮤추얼 파마슈티컬 컴퍼니 아이엔씨. 조절 방출 제형
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
EP2105134A1 (en) 2008-03-24 2009-09-30 Ranbaxy Laboratories Limited Stable amorphous fexofenadine hydrochloride
WO2010083360A2 (en) * 2009-01-16 2010-07-22 Mutual Pharmaceutical Company, Inc. Controlled-release formulations
US9173391B2 (en) 2009-11-06 2015-11-03 Basf Se Crystalline complexes of 4-hydroxy benzoic acid and selected pesticides
ES2403130B1 (es) 2010-06-15 2014-09-29 Chemelectiva S.R.L. Forma polimórfica de clorhidrato de fexofenadina, compuestos intermedios y procedimiento para su preparación
IT1400965B1 (it) * 2010-06-15 2013-07-05 Dipharma Francis Srl Polimorfi di fexofenadina
US9420872B2 (en) * 2010-08-23 2016-08-23 Jason Bird Apparatus and system for holding game-calling devices
JP2012087100A (ja) * 2010-10-21 2012-05-10 Sumitomo Chemical Co Ltd 形態ｉのフェキソフェナジン一塩酸塩の製造方法
CN104072402B (zh) * 2014-07-16 2016-08-17 昆山龙灯瑞迪制药有限公司 一种新结晶形式的盐酸非索非那定化合物及其制备方法

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Also Published As

Publication number Publication date
JP2002255936A (ja) 2002-09-11
JP2010120969A (ja) 2010-06-03
CA2585705A1 (en) 1995-11-23
US7138524B2 (en) 2006-11-21
NO964859D0 (no) 1996-11-15
HU227676B1 (en) 2011-11-28
NO315319B1 (no) 2003-08-18
US20040014976A1 (en) 2004-01-22
CA2189007C (en) 2004-03-02
IL134917A0 (en) 2001-05-20
CA2449419A1 (en) 1995-11-23
CN1623985A (zh) 2005-06-08
US7662835B2 (en) 2010-02-16
US7666881B2 (en) 2010-02-23
ATE220667T1 (de) 2002-08-15
FI964565L (fi) 1996-11-14
HK1098467A1 (en) 2007-07-20
JP2002255935A (ja) 2002-09-11
HU9603167D0 (en) 1997-01-28
US20010025106A1 (en) 2001-09-27
US20080167469A1 (en) 2008-07-10
JP4503907B2 (ja) 2010-07-14
US20010012896A1 (en) 2001-08-09
IL113747A0 (en) 1995-08-31
DK0766668T3 (da) 2002-10-28
CA2189007A1 (en) 1995-11-23
EP0766668B1 (en) 2002-07-17
CN1907967A (zh) 2007-02-07
JPH10500134A (ja) 1998-01-06
HUT76134A (en) 1997-06-30
EP2354125A1 (en) 2011-08-10
JP2002308849A (ja) 2002-10-23
US20020193600A1 (en) 2002-12-19
JP2002316978A (ja) 2002-10-31
AU693892B2 (en) 1998-07-09
US20070021461A1 (en) 2007-01-25
EP0766668A1 (en) 1997-04-09
JP4503909B2 (ja) 2010-07-14
US20010014741A1 (en) 2001-08-16
JP2002308850A (ja) 2002-10-23
HK1137742A1 (en) 2010-08-06
EP1178041A1 (en) 2002-02-06
PT766668E (pt) 2002-11-29
NO964859L (no) 1996-11-15
US7135571B2 (en) 2006-11-14
MX9605613A (es) 1998-05-31
WO1995031437A1 (en) 1995-11-23
US20070021462A1 (en) 2007-01-25
IL113747A (en) 2001-05-20
FI964565A0 (fi) 1996-11-14
US20080167471A1 (en) 2008-07-10
DE69527429T2 (de) 2003-03-20
CN1148849A (zh) 1997-04-30
CN1907967B (zh) 2012-07-04
JP4503908B2 (ja) 2010-07-14
US20020193603A1 (en) 2002-12-19
CA2585705C (en) 2012-04-17
US20020193601A1 (en) 2002-12-19
AU2426595A (en) 1995-12-05
IL134917A (en) 2001-07-24
DE69527429D1 (de) 2002-08-22
CA2449419C (en) 2011-09-06
US20030045721A1 (en) 2003-03-06

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