ES2172692T3 - Procedimiento para la obtencion de aminas opticamente activas. - Google Patents
Procedimiento para la obtencion de aminas opticamente activas.Info
- Publication number
- ES2172692T3 ES2172692T3 ES96939915T ES96939915T ES2172692T3 ES 2172692 T3 ES2172692 T3 ES 2172692T3 ES 96939915 T ES96939915 T ES 96939915T ES 96939915 T ES96939915 T ES 96939915T ES 2172692 T3 ES2172692 T3 ES 2172692T3
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- formula
- aminas
- optically active
- amines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000001412 amines Chemical class 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
LA INVENCION TRATA DE UN PROCEDIMIENTO PARA LA PREPARACION DE AMINAS OPTICAMENTE ACTIVAS DE FORMULA (I*), EN LA CUAL R Y M TIENE LA SIGNIFICACION DADA EN LA DESCRIPCION. EN ESTE PROCEDIMIENTO, LA PREPARACION DE DICHAS AMINAS SE LLEVA A CABO DE MANERA QUE (A) EN UN PRIMER PASO SE HACEN REACCIONAR LAS AMINAS RACEMICAS DE FORMULA (I) EN PRESENCIA DE LIPASAS DE CANDIDA ANTARCTICA Y, OPCIONALMENTE, EN PRESENCIA DE UN DISOLVENTE, CON ESTERES DE FORMULA (II), EN LA CUAL R 1 , R 2 , X Y N TIENEN LA SIGNIFICACION DADA EN LA DESCRIPCION; (B) EN UN SEGUNDO PASO SE SEPARA LA MEZCLA RESULTANTE DE LAS (S) AMINAS DE FORMULA (I S) Y LAS (R) - AMINAS ACILADAS DE FORMULA (III).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19545466 | 1995-12-06 | ||
DE19637336A DE19637336A1 (de) | 1995-12-06 | 1996-09-13 | Verfahren zur Herstellung von optisch aktiven Aminen |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2172692T3 true ES2172692T3 (es) | 2002-10-01 |
Family
ID=26020985
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96939915T Expired - Lifetime ES2172692T3 (es) | 1995-12-06 | 1996-11-25 | Procedimiento para la obtencion de aminas opticamente activas. |
Country Status (7)
Country | Link |
---|---|
US (1) | US6387692B1 (es) |
EP (1) | EP0865500B1 (es) |
JP (2) | JP3714964B2 (es) |
AU (1) | AU2838397A (es) |
DE (1) | DE59608741D1 (es) |
ES (1) | ES2172692T3 (es) |
WO (1) | WO1997020946A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19956786A1 (de) | 1999-11-25 | 2001-05-31 | Basf Ag | Verfahren zur Herstellung optisch aktiver Amine |
KR100423875B1 (ko) * | 2001-12-06 | 2004-03-22 | 주식회사 포스코 | 키랄 아민의 제조 방법 |
DE102005028492A1 (de) * | 2005-06-20 | 2006-12-28 | Basf Ag | Verfahren zur Herstellung von optisch aktiven Aminoalkylphenolen |
WO2007077120A1 (de) * | 2005-12-28 | 2007-07-12 | Basf Se | VERFAHREN ZUR HERSTELLUNG VON (R) - UND (S) -4- (1-AMMONIUMETHYL) BENZOESÄUREMETHYLESTER-SULFAT AUS RACEMISCHEM 4-(l-AMIN0ETHYL)BENZ0ESÄUREMETHYLESTER DURCH LIPASE-KATALYSIERTE ENANTIOSELEKTIVE ACYLIERUNG UND ANSCHLIESSENDEM AUSFÄLLEN MIT SCHWEFELSÄURE |
DE102006028818A1 (de) | 2006-06-21 | 2007-12-27 | Evonik Degussa Gmbh | Verfahren zur Herstellung enantiomerenangereicherter Amine und Amide durch enzymatische Racematspaltung |
JP2010222262A (ja) * | 2009-03-19 | 2010-10-07 | Idemitsu Kosan Co Ltd | アルコキシn,n−ジアルキル酢酸アミドの製造方法、及びポリマー溶液 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4332738A1 (de) * | 1993-09-25 | 1995-03-30 | Basf Ag | Racematspaltung primärer und sekundärer Amine durch Enzym-katalysierte Acylierung |
US6214608B1 (en) * | 1995-02-03 | 2001-04-10 | Basf Aktiengesellschaft | Resolution of racemates of primary and secondary heteroatom-substitued amines by enzyme-catalyzed acylation |
DE19523151A1 (de) | 1995-02-03 | 1996-08-14 | Basf Ag | Racematspaltung primärer und sekundärer heteroatomsubstituierter Amine durch Enzym-katalysierte Acylierung |
DE19534208A1 (de) * | 1995-09-15 | 1997-03-20 | Basf Ag | Spaltung von optisch aktiven Amiden |
DE19621686A1 (de) * | 1996-05-30 | 1997-12-04 | Bayer Ag | Verfahren zur Herstellung von optisch aktiven Aminen |
-
1996
- 1996-11-25 DE DE59608741T patent/DE59608741D1/de not_active Expired - Fee Related
- 1996-11-25 JP JP52093297A patent/JP3714964B2/ja not_active Expired - Fee Related
- 1996-11-25 US US09/077,581 patent/US6387692B1/en not_active Expired - Fee Related
- 1996-11-25 AU AU28383/97A patent/AU2838397A/en not_active Abandoned
- 1996-11-25 EP EP96939915A patent/EP0865500B1/de not_active Revoked
- 1996-11-25 WO PCT/EP1996/005188 patent/WO1997020946A1/de active IP Right Grant
- 1996-11-25 ES ES96939915T patent/ES2172692T3/es not_active Expired - Lifetime
-
2004
- 2004-11-11 JP JP2004328205A patent/JP2005053933A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2005053933A (ja) | 2005-03-03 |
AU2838397A (en) | 1997-06-27 |
WO1997020946A1 (de) | 1997-06-12 |
DE59608741D1 (de) | 2002-03-21 |
EP0865500B1 (de) | 2002-02-13 |
US6387692B1 (en) | 2002-05-14 |
EP0865500A1 (de) | 1998-09-23 |
JP3714964B2 (ja) | 2005-11-09 |
JP2000501292A (ja) | 2000-02-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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