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ES2172023T3 - Nuevos derivados tetrahidro-piridinicos sustituidos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. - Google Patents

Nuevos derivados tetrahidro-piridinicos sustituidos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Info

Publication number
ES2172023T3
ES2172023T3 ES97948974T ES97948974T ES2172023T3 ES 2172023 T3 ES2172023 T3 ES 2172023T3 ES 97948974 T ES97948974 T ES 97948974T ES 97948974 T ES97948974 T ES 97948974T ES 2172023 T3 ES2172023 T3 ES 2172023T3
Authority
ES
Spain
Prior art keywords
tetrahydra
pharmaceutical compositions
compositions containing
preparation procedure
new substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97948974T
Other languages
English (en)
Inventor
Christian Marazano
Delphine Compere
C Bhupesh Das
Jean Lepagnol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Les Laboratoires Servier SAS
Original Assignee
Les Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Servier SAS filed Critical Les Laboratoires Servier SAS
Application granted granted Critical
Publication of ES2172023T3 publication Critical patent/ES2172023T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA INVENCION SE REFIERE A LOS COMPUESTOS DE FORMULA GENERAL (I) EN LA QUE R, R 1 , R 2 , X E Y SON TALES COMO SE DEFINEN EN LA DESCRIPCION, SUS ISOMEROS GEOMETRICOS Y/O OPTICOS Y SUS SALES DE ADICION A UN ACIDO O UNA BASE FARMACEUTICAMENTE ACEPTABLES. APLICACION: MEDICAMENTOS.
ES97948974T 1996-12-05 1997-12-02 Nuevos derivados tetrahidro-piridinicos sustituidos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. Expired - Lifetime ES2172023T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9614951A FR2756826B1 (fr) 1996-12-05 1996-12-05 Nouveaux derives tetrahydropyridiniques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ES2172023T3 true ES2172023T3 (es) 2002-09-16

Family

ID=9498371

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97948974T Expired - Lifetime ES2172023T3 (es) 1996-12-05 1997-12-02 Nuevos derivados tetrahidro-piridinicos sustituidos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Country Status (18)

Country Link
US (1) US6232319B1 (es)
EP (1) EP0937043B1 (es)
JP (1) JP3872821B2 (es)
CN (1) CN1126739C (es)
AT (1) ATE214051T1 (es)
AU (1) AU719208B2 (es)
CA (1) CA2274133C (es)
DE (1) DE69710909T2 (es)
DK (1) DK0937043T3 (es)
ES (1) ES2172023T3 (es)
FR (1) FR2756826B1 (es)
HU (1) HUP0001773A3 (es)
NO (1) NO313589B1 (es)
NZ (1) NZ336111A (es)
PL (1) PL189372B1 (es)
PT (1) PT937043E (es)
WO (1) WO1998024765A1 (es)
ZA (1) ZA9710960B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2793245B1 (fr) * 1999-05-05 2002-10-11 Adir Nouveaux composes pyridiniques ou piperidiniques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
WO2004052365A2 (en) * 2002-12-06 2004-06-24 North Shore-Long Island Jewish Research Institute Inhibition of inflamation using alpha 7 receptor-binding cholinergic agonists
US7238715B2 (en) * 2002-12-06 2007-07-03 The Feinstein Institute For Medical Research Treatment of pancreatitis using alpha 7 receptor-binding cholinergic agonists
US8316104B2 (en) 2005-11-15 2012-11-20 California Institute Of Technology Method and apparatus for collaborative system
PE20110711A1 (es) 2008-11-19 2011-10-11 Envivo Pharmaceuticals Inc Tratamiento de trastornos cognitivos con (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida y sales farmaceuticamente aceptables de la misma
TW201031664A (en) 2009-01-26 2010-09-01 Targacept Inc Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
EP2429518A1 (en) * 2009-05-11 2012-03-21 Envivo Pharmaceuticals, Inc. Treatment of cognitive disorders with certain alpha-7 nicotinic acid receptors in combination with acetylcholinesterase inhibitors
MX2012013345A (es) 2010-05-17 2013-02-11 Envivo Pharmaceuticals Inc Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin- 3-il)benzo[b]tiofeno-2-carboxamida monohidratado.
RU2635522C2 (ru) 2012-05-08 2017-11-13 Форум Фармасьютикалз, Инк. Способы поддержания, лечения или улучшения когнитивной функции

Also Published As

Publication number Publication date
NO313589B1 (no) 2002-10-28
HK1023346A1 (en) 2000-09-08
DK0937043T3 (da) 2002-06-10
CN1126739C (zh) 2003-11-05
WO1998024765A1 (fr) 1998-06-11
AU7624398A (en) 1998-06-29
US6232319B1 (en) 2001-05-15
ATE214051T1 (de) 2002-03-15
JP3872821B2 (ja) 2007-01-24
CN1239951A (zh) 1999-12-29
NZ336111A (en) 2000-03-27
NO992731L (no) 1999-06-04
CA2274133A1 (fr) 1998-06-11
EP0937043B1 (fr) 2002-03-06
FR2756826B1 (fr) 1999-01-08
HUP0001773A3 (en) 2002-12-28
EP0937043A1 (fr) 1999-08-25
HUP0001773A2 (hu) 2000-11-28
DE69710909D1 (de) 2002-04-11
FR2756826A1 (fr) 1998-06-12
PL189372B1 (pl) 2005-07-29
PT937043E (pt) 2002-07-31
CA2274133C (fr) 2003-09-16
DE69710909T2 (de) 2002-11-07
AU719208B2 (en) 2000-05-04
JP2001505214A (ja) 2001-04-17
NO992731D0 (no) 1999-06-04
ZA9710960B (en) 1998-06-15

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