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ES2169681A1 - Metodo de produccion de filmes de quitosan con una alta capacidad de adherencia celular, producto obrenido y aplicaciones. - Google Patents

Metodo de produccion de filmes de quitosan con una alta capacidad de adherencia celular, producto obrenido y aplicaciones.

Info

Publication number
ES2169681A1
ES2169681A1 ES200002057A ES200002057A ES2169681A1 ES 2169681 A1 ES2169681 A1 ES 2169681A1 ES 200002057 A ES200002057 A ES 200002057A ES 200002057 A ES200002057 A ES 200002057A ES 2169681 A1 ES2169681 A1 ES 2169681A1
Authority
ES
Spain
Prior art keywords
chitosan
applications
production
film
resulting product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES200002057A
Other languages
English (en)
Other versions
ES2169681B1 (es
Inventor
Lacomba Jose Luis Lopez
Cantalejo Jesus Manuel Garcia
Casado Jose Vicente Sanz
Viviana Monica Ramos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OSFARMA SL
Original Assignee
OSFARMA SL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES200002057A priority Critical patent/ES2169681B1/es
Application filed by OSFARMA SL filed Critical OSFARMA SL
Priority to JP2002517114A priority patent/JP5366350B2/ja
Priority to AU2001282153A priority patent/AU2001282153A1/en
Priority to PCT/ES2001/000322 priority patent/WO2002011782A1/es
Priority to AT01960753T priority patent/ATE295190T1/de
Priority to ES01960753T priority patent/ES2246337T3/es
Priority to DE60110801T priority patent/DE60110801T2/de
Priority to BR0113106-0A priority patent/BR0113106A/pt
Priority to EP01960753A priority patent/EP1308177B1/en
Publication of ES2169681A1 publication Critical patent/ES2169681A1/es
Priority to US10/364,827 priority patent/US20030124172A1/en
Application granted granted Critical
Publication of ES2169681B1 publication Critical patent/ES2169681B1/es
Priority to US12/361,729 priority patent/US20090186066A1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Medicinal Preparation (AREA)

Abstract

Método de producción de filmes de quitosán con una alta capacidad de adherencia celular, producto obtenido y aplicaciones. Dicho método comprende las siguientes etapas: (a) formación de un filme de quitosán; (b) estabilización de dicho filme de quitosán; (c) tratamiento activador de la adherencia celular de dicho filme estabilizado; (d) tratamiento de activación biológica de dicho filme procedente de dicha etapa (c), pudiendo llevarse a cabo el tratamiento de la etapa (d) en cualquier momento del procesado y no necesariamente como etapa final del mismo. Los citados filmes así obtenidos poseen una alta capacidad de adherencia celular con una elevada uniformidad en la adhesión y están activados biológicamente. Los filmes se utilizan para inducir el desarrollo biológico deseado en un organismo receptor, por ejemplo osteointegración de implantes y regeneración de tejidos óseos.
ES200002057A 2000-08-10 2000-08-10 Metodo de produccion de filmes de quitosan con una alta capacidad de adherencia celular, producto obrenido y aplicaciones. Expired - Fee Related ES2169681B1 (es)

Priority Applications (11)

Application Number Priority Date Filing Date Title
ES200002057A ES2169681B1 (es) 2000-08-10 2000-08-10 Metodo de produccion de filmes de quitosan con una alta capacidad de adherencia celular, producto obrenido y aplicaciones.
EP01960753A EP1308177B1 (en) 2000-08-10 2001-08-10 Method for the production of chitosan-based films with enhanced cell adhering capacity, resulting product and applications
PCT/ES2001/000322 WO2002011782A1 (es) 2000-08-10 2001-08-10 Metodo de produccion de filmes a base de quitosan con capacidad de adherencia celular aumentada, producto obtenido y aplicaciones
AT01960753T ATE295190T1 (de) 2000-08-10 2001-08-10 Verfahren zur herstellung von auf chitosan basierenden filmen mit verbessertem zellanhaftvermögen, daraus resultierendes produkt and anwendungen
ES01960753T ES2246337T3 (es) 2000-08-10 2001-08-10 Metodo de produccion de peliculas a base de quitosan con capacidad de adherencia celular aumentada, producto obtenido y aplicaciones.
DE60110801T DE60110801T2 (de) 2000-08-10 2001-08-10 Verfahren zur herstellung von auf chitosan basierenden filmen mit verbessertem zellanhaftvermögen, daraus resultierendes produkt and anwendungen
JP2002517114A JP5366350B2 (ja) 2000-08-10 2001-08-10 高い細胞接着能を有するキトサン系フィルムの製造方法および用途、ならびに該フィルムを被覆した製品
AU2001282153A AU2001282153A1 (en) 2000-08-10 2001-08-10 Method for the production of chitosan-based films with enhanced cell adhering capacity, resulting product and applications
BR0113106-0A BR0113106A (pt) 2000-08-10 2001-08-10 Método para a produção de filmes à base de quitosan com capacidade de aderência celular acentuada, produto resultante e aplicações
US10/364,827 US20030124172A1 (en) 2000-08-10 2003-02-10 Method for production of chitosan-based films with enhanced cell adhering capacity, resulting product and applications
US12/361,729 US20090186066A1 (en) 2000-08-10 2009-01-29 Method for production of chitosan-based films with enhanced cell adhering capacity, resulting product and applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200002057A ES2169681B1 (es) 2000-08-10 2000-08-10 Metodo de produccion de filmes de quitosan con una alta capacidad de adherencia celular, producto obrenido y aplicaciones.

Publications (2)

Publication Number Publication Date
ES2169681A1 true ES2169681A1 (es) 2002-07-01
ES2169681B1 ES2169681B1 (es) 2003-10-01

Family

ID=8494684

Family Applications (2)

Application Number Title Priority Date Filing Date
ES200002057A Expired - Fee Related ES2169681B1 (es) 2000-08-10 2000-08-10 Metodo de produccion de filmes de quitosan con una alta capacidad de adherencia celular, producto obrenido y aplicaciones.
ES01960753T Expired - Lifetime ES2246337T3 (es) 2000-08-10 2001-08-10 Metodo de produccion de peliculas a base de quitosan con capacidad de adherencia celular aumentada, producto obtenido y aplicaciones.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES01960753T Expired - Lifetime ES2246337T3 (es) 2000-08-10 2001-08-10 Metodo de produccion de peliculas a base de quitosan con capacidad de adherencia celular aumentada, producto obtenido y aplicaciones.

Country Status (9)

Country Link
US (2) US20030124172A1 (es)
EP (1) EP1308177B1 (es)
JP (1) JP5366350B2 (es)
AT (1) ATE295190T1 (es)
AU (1) AU2001282153A1 (es)
BR (1) BR0113106A (es)
DE (1) DE60110801T2 (es)
ES (2) ES2169681B1 (es)
WO (1) WO2002011782A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10338110A1 (de) * 2003-08-15 2005-03-10 Biomet Deutschland Gmbh Mit Chitosan beschichteter metallischer Gegenstand sowie Verfahren zu dessen Herstellung
AU2004289287A1 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
KR100987818B1 (ko) * 2003-11-26 2010-10-13 에스케이케미칼주식회사 수용성 키토산으로 코팅된 알긴산 스폰지 및 이의 제조방법
KR100993006B1 (ko) * 2003-11-26 2010-11-09 에스케이케미칼주식회사 키토산으로 코팅된 알긴산 스폰지 및 이의 제조방법
IS7572A (is) * 2004-11-29 2006-05-30 Genis Ehf Aðferð og efni til lækninga
ITMI20061373A1 (it) * 2006-07-14 2008-01-15 Sirc S P A Natural & Dietetic Foods Chitine e chitosani in forma attivata e loro proprieta' dimagranti ipoglicemizzanti e ipolipemizzanti
US8133553B2 (en) 2007-06-18 2012-03-13 Zimmer, Inc. Process for forming a ceramic layer
US8309521B2 (en) 2007-06-19 2012-11-13 Zimmer, Inc. Spacer with a coating thereon for use with an implant device
US8608049B2 (en) 2007-10-10 2013-12-17 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
DE102008053892A1 (de) 2008-10-30 2010-05-06 Fachhochschule Gelsenkirchen Medizinisches Implantat mit biofunktionalisierter Oberfläche
WO2010107794A2 (en) 2009-03-16 2010-09-23 University Of Memphis Research Foundation Compositions and methods for delivering an agent to a wound
CN102051355B (zh) * 2010-12-03 2012-08-22 江南大学 一种固定化酸性脲酶酶膜的制备方法及应用
FR2985908B1 (fr) 2012-01-24 2014-02-07 Univ Claude Bernard Lyon Substrat sur lequel est greffe par liaison covalente du chitosane ou du collagene
WO2014142915A1 (en) 2013-03-14 2014-09-18 University Of Memphis Research Foundation Methods for producing a biodegradable chitosan composition and uses thereof
CN103893835B (zh) * 2014-04-15 2016-05-04 青岛大学 一种可降解的壳聚糖生物膜及其制备方法及应用
KR101933701B1 (ko) * 2016-12-29 2018-12-28 전남대학교산학협력단 생체적합성세라믹스 코팅층, 그 코팅층을 포함하는 티타늄재구조체 및 그 구조체 제조방법
CN114763543A (zh) * 2021-01-15 2022-07-19 百瑞全球有限公司 膜状固定化细胞、多肽、寡肽或蛋白质及其制备方法

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4326532A (en) * 1980-10-06 1982-04-27 Minnesota Mining And Manufacturing Company Antithrombogenic articles
US5116824A (en) * 1985-05-02 1992-05-26 Katakura Chikkarin Co., Ltd. Biomaterial comprising a composite material of a chitosan derivative and collagen derivative
EP0555807A1 (en) * 1992-02-10 1993-08-18 Matsumoto Dental College Bone substitute product and method of producing the same
WO1995030403A1 (en) * 1994-05-04 1995-11-16 Medicarb Ab Oral hygiene composition
WO1996002259A1 (en) * 1994-07-19 1996-02-01 Astra Aktiebolag Hard tissue stimulating agent
WO1996002258A1 (en) * 1994-07-19 1996-02-01 Astra Aktiebolag Anti-adhesion agent
EP0754466A2 (en) * 1995-07-20 1997-01-22 Matsumoto Dental College Osteoinduction substance, method of manufacturing the same, and bone filling material including the same
EP0784985A1 (en) * 1994-09-30 1997-07-23 Yamanouchi Pharmaceutical Co. Ltd. Osteoplastic graft

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601371B1 (fr) * 1986-07-11 1989-05-12 Merieux Inst Procede de traitement du collagene en vue, notamment, d'en faciliter la reticulation et collagene obtenu par application dudit procede
JP3208586B2 (ja) * 1992-02-10 2001-09-17 学校法人松本歯科大学 シート状骨補填剤の製造方法
JP3208585B2 (ja) * 1992-02-10 2001-09-17 学校法人松本歯科大学 硬化型中性骨形成物の製造方法
GB2275686B (en) * 1993-03-03 1997-04-30 Johnson & Johnson Medical Swellable wound dressing materials
JP2986551B2 (ja) * 1994-09-30 1999-12-06 山之内製薬株式会社 骨形成用移植体
US5830883A (en) * 1995-11-06 1998-11-03 Duquesne University Of The Holy Ghost Methods of creating a unique chitosan and employing the same to form complexes with drugs, delivery of the same within a patient and a related dosage form
US5885609A (en) * 1997-05-23 1999-03-23 Northeastern University Biocompatible articles and method for making same
US6752831B2 (en) * 2000-12-08 2004-06-22 Osteotech, Inc. Biocompatible osteogenic band for repair of spinal disorders

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4326532A (en) * 1980-10-06 1982-04-27 Minnesota Mining And Manufacturing Company Antithrombogenic articles
US5116824A (en) * 1985-05-02 1992-05-26 Katakura Chikkarin Co., Ltd. Biomaterial comprising a composite material of a chitosan derivative and collagen derivative
EP0555807A1 (en) * 1992-02-10 1993-08-18 Matsumoto Dental College Bone substitute product and method of producing the same
WO1995030403A1 (en) * 1994-05-04 1995-11-16 Medicarb Ab Oral hygiene composition
WO1996002259A1 (en) * 1994-07-19 1996-02-01 Astra Aktiebolag Hard tissue stimulating agent
WO1996002258A1 (en) * 1994-07-19 1996-02-01 Astra Aktiebolag Anti-adhesion agent
EP0784985A1 (en) * 1994-09-30 1997-07-23 Yamanouchi Pharmaceutical Co. Ltd. Osteoplastic graft
EP0754466A2 (en) * 1995-07-20 1997-01-22 Matsumoto Dental College Osteoinduction substance, method of manufacturing the same, and bone filling material including the same

Also Published As

Publication number Publication date
US20090186066A1 (en) 2009-07-23
ES2169681B1 (es) 2003-10-01
DE60110801D1 (de) 2005-06-16
ES2246337T3 (es) 2006-02-16
AU2001282153A1 (en) 2002-02-18
US20030124172A1 (en) 2003-07-03
EP1308177A1 (en) 2003-05-07
ATE295190T1 (de) 2005-05-15
BR0113106A (pt) 2003-07-15
JP5366350B2 (ja) 2013-12-11
WO2002011782A1 (es) 2002-02-14
WO2002011782A8 (es) 2002-07-11
DE60110801T2 (de) 2006-01-26
EP1308177B1 (en) 2005-05-11
JP2004505678A (ja) 2004-02-26

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