ES2150103T3 - Oligonucleotidos de amplificacion de acido nucleico y sondas para borrelia asociados con la enfermedad de lyme. - Google Patents
Oligonucleotidos de amplificacion de acido nucleico y sondas para borrelia asociados con la enfermedad de lyme.Info
- Publication number
- ES2150103T3 ES2150103T3 ES96903627T ES96903627T ES2150103T3 ES 2150103 T3 ES2150103 T3 ES 2150103T3 ES 96903627 T ES96903627 T ES 96903627T ES 96903627 T ES96903627 T ES 96903627T ES 2150103 T3 ES2150103 T3 ES 2150103T3
- Authority
- ES
- Spain
- Prior art keywords
- borrelia
- lyme disease
- nucleic acid
- acid amplification
- amplification oligonucleotides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000016604 Lyme disease Diseases 0.000 title abstract 8
- 241000589968 Borrelia Species 0.000 title abstract 5
- 239000000523 sample Substances 0.000 title abstract 4
- 230000003321 amplification Effects 0.000 title abstract 3
- 238000003199 nucleic acid amplification method Methods 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108091034117 Oligonucleotide Proteins 0.000 title 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title 1
- 238000009396 hybridization Methods 0.000 abstract 3
- 241000589978 Borrelia hermsii Species 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
LA PRESENTE INVENCION DESCRIBE MUESTRAS DE ENSAYOS DE HIBRIDACION, INICIADORES DE AMPLIFICACION, COMPOSICIONES DE ACIDOS NUCLEICOS Y METODOS UTILES PARA DETECTAR ACIDOS NUCLEICOS DE BORRELIA. SE DESCRIBEN MUESTRAS DE ENSAYOS DE HIBRIDACION Y LOS INICIADORES DE AMPLIFICACION QUE DETECTAN SELECTIVAMENTE BORRELIA ASOCIADA A LA ENFERMEDAD DE LYME Y DISTINGUEN ESTA BORRELIA DE BORRELIA HERMSII, ASI COMO OTRAS MUESTRAS DE HIBRIDACION QUE DETECTAN SELECTIVAMENTE BORRELIA HERMSII Y NO BORRELIA ASOCIADA A LA ENFERMEDAD DE LYME.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37486395A | 1995-01-19 | 1995-01-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2150103T3 true ES2150103T3 (es) | 2000-11-16 |
Family
ID=23478499
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96903627T Expired - Lifetime ES2150103T3 (es) | 1995-01-19 | 1996-01-18 | Oligonucleotidos de amplificacion de acido nucleico y sondas para borrelia asociados con la enfermedad de lyme. |
Country Status (10)
Country | Link |
---|---|
US (1) | US6074826A (es) |
EP (1) | EP0805876B1 (es) |
JP (3) | JP3124036B2 (es) |
AT (1) | ATE194391T1 (es) |
AU (1) | AU689375B2 (es) |
CA (1) | CA2209991C (es) |
DE (1) | DE69609161T2 (es) |
DK (1) | DK0805876T3 (es) |
ES (1) | ES2150103T3 (es) |
WO (1) | WO1996022392A2 (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6280946B2 (en) | 1998-08-07 | 2001-08-28 | Boston Probes, Inc. | PNA probes, probe sets, methods and kits pertaining to the universal detection of bacteria and eucarya |
US7108980B1 (en) | 1998-08-07 | 2006-09-19 | Boston Probes, Inc. | Methods for the analysis of microcolonies of bacteria and yeast |
JP4854853B2 (ja) | 1998-11-12 | 2012-01-18 | ライフ テクノロジーズ コーポレーション | トランスフェクション薬剤 |
ATE437242T1 (de) * | 1999-05-03 | 2009-08-15 | Gen Probe Inc | Polynukleotidmatrix-basiertes verfahren zur identifizierung von mikroorganismen |
US6821770B1 (en) | 1999-05-03 | 2004-11-23 | Gen-Probe Incorporated | Polynucleotide matrix-based method of identifying microorganisms |
EP1925678B1 (en) * | 1999-05-03 | 2009-07-22 | Gen-Probe Incorporated | Polynucleotide matrix-based method of identifying microorganisms |
JP2001258570A (ja) * | 2000-03-17 | 2001-09-25 | Tosoh Corp | 腸炎ビブリオ菌検出用のオリゴヌクレオチド |
JP2001258569A (ja) * | 2000-03-17 | 2001-09-25 | Tosoh Corp | 腸炎ビブリオ菌検出のためのオリゴヌクレオチド |
AU9066001A (en) * | 2000-09-08 | 2002-03-22 | Invitrogen Corporation | Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis |
DE10048009A1 (de) * | 2000-09-26 | 2002-04-11 | Cytonet Gmbh & Co Kg | Verfahren zum Nachweis von Pilzinfektionen |
MXPA04001480A (es) * | 2001-08-17 | 2004-05-20 | Bioniche Life Sciences Inc | Composiciones de oligonucleotido y su uso para inducir apoptosis. |
WO2003029450A1 (en) * | 2001-09-28 | 2003-04-10 | Københavns Universitet | Nucleic acid sequences encoding lysk from different borrelia strains and uses thereof |
US20050221414A1 (en) | 2004-03-31 | 2005-10-06 | Katalin Varadi | Kit for measuring the thrombin generation in a sample of a patient's blood or plasma |
KR100850193B1 (ko) | 2004-08-28 | 2008-08-04 | 주식회사 진인 | 모든 세균의 감별을 위한 세균 특이적, 속 특이적 및 종특이적 올리고뉴클레오티드, 이를 포함하는 진단 키트, 및이를 이용한 검출 방법 |
EP1861414B9 (en) * | 2005-02-07 | 2011-04-06 | Gen-Probe Incorporated | Compositions and methods for detecting group b streptococci |
US7482127B2 (en) * | 2005-11-03 | 2009-01-27 | Third Wave Technologies, Inc. | Nucleic acid detection assays employing blocker oligonucleotides |
EP1978111B1 (en) * | 2007-04-02 | 2013-03-27 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of Pseudomonas aeruginosa |
EP2829616B1 (en) * | 2009-06-23 | 2018-09-26 | Gen-Probe Incorporated | Composition and methods for detecting nucleic acid from mollicutes |
US20120100549A1 (en) * | 2010-10-01 | 2012-04-26 | Ibis Biosciences, Inc. | Targeted genome amplification methods |
EP2702166B1 (en) * | 2011-04-25 | 2018-06-06 | Gen-Probe Incorporated | Compositions and methods for detecting bv-associated bacterial nucleic acid |
WO2016011203A1 (en) | 2014-07-15 | 2016-01-21 | Life Technologies Corporation | Compositions with lipid aggregates and methods for efficient delivery of molecules to cells |
EP3469103B1 (en) * | 2016-06-10 | 2021-10-06 | Gen-Probe Incorporated | Compositions and methods for detecting zika virus nucleic acid |
WO2018094171A1 (en) | 2016-11-21 | 2018-05-24 | Gen-Probe Incorporated | Compositions and methods for detecting or quantifying hepatitis b virus |
US10718767B2 (en) * | 2018-03-09 | 2020-07-21 | Id-Fish Technology, Inc. | Species specific antigen sequences for tick-borne relapsing fever (TBRF) and methods of use |
CN113186317A (zh) * | 2021-05-31 | 2021-07-30 | 上海基灵生物科技有限公司 | 一种检测人畜共患病病原体的核酸组合物、试剂盒及其应用 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60501339A (ja) * | 1983-01-10 | 1985-08-22 | ジエン−プロ−ブ インコ−ポレィテッド | 生物を検出、同定又は定量する方法およびキット |
DE3752172T3 (de) * | 1986-11-24 | 2008-04-10 | Gen-Probe Inc., San Diego | Nukleinsäuresonden zum Nachweis und/oder zur Quantifizierung von nicht-viralen Organismen |
US5283174A (en) * | 1987-09-21 | 1994-02-01 | Gen-Probe, Incorporated | Homogenous protection assay |
CA1339872C (en) * | 1987-09-21 | 1998-05-19 | Lyle John Arnold Jr. | Homogeneous protection assay |
US5185439A (en) * | 1987-10-05 | 1993-02-09 | Gen-Probe Incorporated | Acridinium ester labelling and purification of nucleotide probes |
US5030557A (en) * | 1987-11-24 | 1991-07-09 | Ml Technology Venture | Means and method for enhancing nucleic acid hybridization |
US5449769A (en) * | 1989-03-06 | 1995-09-12 | Gen-Probe Incorporated | Method and reagent for sulfurization of organophosphorous compounds |
CA2025178A1 (en) * | 1989-10-02 | 1991-04-03 | William G. Weisburg | Nucleic acid probes for the detection of lyme disease spirochetes |
JP2819166B2 (ja) * | 1989-10-03 | 1998-10-30 | キヤノン株式会社 | 放射光用光学素子の汚れ除去装置および方法 |
US5912117A (en) * | 1990-03-07 | 1999-06-15 | Roche Molecular Systems, Inc. | Method for diagnosis of lyme disease |
WO1992007864A1 (en) * | 1990-10-26 | 1992-05-14 | Genta Incorporated | Improved process for the synthesis of oligomers |
KR100316498B1 (ko) * | 1992-08-04 | 2002-06-20 | 다니엘 엘. 캐시앙, 헨리 엘. 노르호프, 피터 알. 쉬어리 | 핵산서열증폭방법 |
-
1996
- 1996-01-18 AT AT96903627T patent/ATE194391T1/de not_active IP Right Cessation
- 1996-01-18 DE DE69609161T patent/DE69609161T2/de not_active Expired - Fee Related
- 1996-01-18 DK DK96903627T patent/DK0805876T3/da active
- 1996-01-18 EP EP96903627A patent/EP0805876B1/en not_active Expired - Lifetime
- 1996-01-18 JP JP08522436A patent/JP3124036B2/ja not_active Expired - Fee Related
- 1996-01-18 AU AU47644/96A patent/AU689375B2/en not_active Ceased
- 1996-01-18 CA CA002209991A patent/CA2209991C/en not_active Expired - Fee Related
- 1996-01-18 ES ES96903627T patent/ES2150103T3/es not_active Expired - Lifetime
- 1996-01-18 WO PCT/US1996/000889 patent/WO1996022392A2/en not_active Application Discontinuation
-
1997
- 1997-10-17 US US08/953,094 patent/US6074826A/en not_active Expired - Lifetime
-
2000
- 2000-08-15 JP JP2000246417A patent/JP4070394B2/ja not_active Expired - Fee Related
-
2007
- 2007-09-19 JP JP2007241752A patent/JP2008022858A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DK0805876T3 (da) | 2000-11-06 |
EP0805876A2 (en) | 1997-11-12 |
AU689375B2 (en) | 1998-03-26 |
WO1996022392A2 (en) | 1996-07-25 |
JP2001078789A (ja) | 2001-03-27 |
EP0805876B1 (en) | 2000-07-05 |
WO1996022392A3 (en) | 1996-09-12 |
CA2209991A1 (en) | 1996-07-25 |
JPH10503382A (ja) | 1998-03-31 |
DE69609161T2 (de) | 2001-03-22 |
DE69609161D1 (de) | 2000-08-10 |
CA2209991C (en) | 2005-04-12 |
JP3124036B2 (ja) | 2001-01-15 |
US6074826A (en) | 2000-06-13 |
ATE194391T1 (de) | 2000-07-15 |
JP2008022858A (ja) | 2008-02-07 |
JP4070394B2 (ja) | 2008-04-02 |
AU4764496A (en) | 1996-08-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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