ES2148234T3 - Composicion farmaceutica a base de flavopereirina y su utilizacion en el tratamiento del virus vih. - Google Patents
Composicion farmaceutica a base de flavopereirina y su utilizacion en el tratamiento del virus vih.Info
- Publication number
- ES2148234T3 ES2148234T3 ES93916037T ES93916037T ES2148234T3 ES 2148234 T3 ES2148234 T3 ES 2148234T3 ES 93916037 T ES93916037 T ES 93916037T ES 93916037 T ES93916037 T ES 93916037T ES 2148234 T3 ES2148234 T3 ES 2148234T3
- Authority
- ES
- Spain
- Prior art keywords
- flavopereirine
- pct
- date feb
- treatment
- sec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- BAALMEGRQMMBJQ-UHFFFAOYSA-N Flavopereirine Natural products N1=C2C=CC=CC2=C2C1=C1C=CC(CC)=CN1C=C2 BAALMEGRQMMBJQ-UHFFFAOYSA-N 0.000 title abstract 6
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- MGHKUXYLAVTETL-UHFFFAOYSA-N 3-ethyl-12h-indolo[2,3-a]quinolizin-5-ium;chloride Chemical compound [Cl-].N1C2=CC=CC=C2C2=C1C1=CC=C(CC)C=[N+]1C=C2 MGHKUXYLAVTETL-UHFFFAOYSA-N 0.000 abstract 5
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 241000282412 Homo Species 0.000 abstract 1
- 241000713772 Human immunodeficiency virus 1 Species 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
LA COMPOSICION CONFORME A LA INVENCION LLEVA FLAVOPEREIRINA, O UNA SAL U OTRO DERIVADO FARMACOLOGICAMENTE ACEPTABLE DE ESTA, COMO UNICO PRINCIPIO ACTIVO. SE PRESENTA EN FORMA SOLIDA, CONTENIENDO ENTRE 250 Y 500 MG DE PRINCIPIO ACTIVO, ADMINISTRABLE POR VIA ORAL, CON LA DOSIS DIARIA DE 1 A 3 G. APLICACIONES AL TRATAMIENTO DE LOS SERES HUMANO QUE PADECEN EL VIH-1 Y A LOS ENFERMOS DEL SIDA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9209284A FR2694693B1 (fr) | 1992-07-28 | 1992-07-28 | Composition pharmaceutique à base de flavopéréirine et son utilisation dans un traitement contre le virus VIH. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2148234T3 true ES2148234T3 (es) | 2000-10-16 |
Family
ID=9432328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93916037T Expired - Lifetime ES2148234T3 (es) | 1992-07-28 | 1993-07-26 | Composicion farmaceutica a base de flavopereirina y su utilizacion en el tratamiento del virus vih. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5519028A (es) |
| EP (1) | EP0605700B1 (es) |
| JP (1) | JPH07502754A (es) |
| AT (1) | ATE192926T1 (es) |
| CA (1) | CA2120001C (es) |
| DE (1) | DE69328667T2 (es) |
| ES (1) | ES2148234T3 (es) |
| FR (1) | FR2694693B1 (es) |
| IL (1) | IL106491A (es) |
| PT (1) | PT605700E (es) |
| WO (1) | WO1994002146A1 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050159400A1 (en) * | 2003-07-22 | 2005-07-21 | Hamann Mark T. | Manzamines in the treatment of infectious disease |
| US20070027076A1 (en) | 2003-09-09 | 2007-02-01 | Fumapham Ag | Use of fumaric acid derivatives for treating cardiac insufficiency, and asthma |
| CA2578549C (en) * | 2004-05-19 | 2014-09-02 | Natural Source International | Flavopereirine and alstonine combinations in the treatment and prevention of prostate cancer |
| US20100256177A1 (en) * | 2004-06-11 | 2010-10-07 | Seshagiri Venkatachalam | Flavopereirine derivatives for cancer therapy |
| LT1799196T (lt) | 2004-10-08 | 2016-09-12 | Forward Pharma A/S | Kontroliuojamo atpalaidavimo farmacinė kompozicija, apimanti fumaro rūgšties esterį |
| HUE032251T2 (en) * | 2007-02-08 | 2017-09-28 | Biogen Ma Inc | Neuroprotection in demyelinating diseases |
| JP7491514B2 (ja) | 2018-03-31 | 2024-05-28 | モレキュラー インターナショナル リサーチ， インコーポレーテッド | 予防及び治療に有効な選択的抗がん剤 |
| KR20220066302A (ko) * | 2019-09-11 | 2022-05-24 | 더 스크립스 리서치 인스티튜트 | 항바이러스 전구약물 및 이의 제형 |
| US20230060934A1 (en) * | 2021-08-25 | 2023-03-02 | Michael Wayne Dockery | Botanical antiviral nutritional supplement |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2450607A2 (fr) * | 1978-03-13 | 1980-10-03 | Beljanski Mirko | Composition pharmaceutique contenant comme principe actif la flavopereine |
| DE3172570D1 (en) * | 1981-03-11 | 1985-11-14 | Mirko Beljanski | Serpentine, alstonine and sempervirine drugs for the specific inhibition of tumurous and cancerous cells |
| FR2633182B1 (fr) * | 1988-06-23 | 1993-07-23 | Beljanski Mirko | Composition pharmaceutique anticancereuse et methode d'utilisation de l'invention |
| FR2639830B1 (fr) * | 1988-12-02 | 1991-03-22 | Beljanski Mirko | Composition antivirale et ses applications |
| US5011853A (en) * | 1989-08-25 | 1991-04-30 | Washington University | Compounds for treatment of cholinergic neurotoxins |
| CH679982A5 (en) * | 1990-01-19 | 1992-05-29 | Debiopharm Sa | Anti-retroviral compsn. contg. 2-methyl-9-hydroxy-ellipticine acetate - esp. for treatment or prevention of AIDS with greater activity than AZT |
-
1992
- 1992-07-28 FR FR9209284A patent/FR2694693B1/fr not_active Expired - Fee Related
-
1993
- 1993-07-26 EP EP93916037A patent/EP0605700B1/fr not_active Expired - Lifetime
- 1993-07-26 JP JP6504224A patent/JPH07502754A/ja active Pending
- 1993-07-26 AT AT93916037T patent/ATE192926T1/de not_active IP Right Cessation
- 1993-07-26 US US08/196,164 patent/US5519028A/en not_active Expired - Lifetime
- 1993-07-26 PT PT93916037T patent/PT605700E/pt unknown
- 1993-07-26 CA CA002120001A patent/CA2120001C/en not_active Expired - Fee Related
- 1993-07-26 ES ES93916037T patent/ES2148234T3/es not_active Expired - Lifetime
- 1993-07-26 WO PCT/FR1993/000761 patent/WO1994002146A1/fr active IP Right Grant
- 1993-07-26 DE DE69328667T patent/DE69328667T2/de not_active Expired - Fee Related
- 1993-07-27 IL IL10649193A patent/IL106491A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69328667T2 (de) | 2001-02-08 |
| DE69328667D1 (de) | 2000-06-21 |
| FR2694693B1 (fr) | 1994-10-28 |
| JPH07502754A (ja) | 1995-03-23 |
| WO1994002146A1 (fr) | 1994-02-03 |
| IL106491A (en) | 1998-12-06 |
| CA2120001C (en) | 2005-02-08 |
| CA2120001A1 (en) | 1994-02-03 |
| IL106491A0 (en) | 1993-11-15 |
| EP0605700B1 (fr) | 2000-05-17 |
| US5519028A (en) | 1996-05-21 |
| FR2694693A1 (fr) | 1994-02-18 |
| ATE192926T1 (de) | 2000-06-15 |
| PT605700E (pt) | 2000-12-29 |
| EP0605700A1 (fr) | 1994-07-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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