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ES2146722T3 - Nuevos analogos de la acronicina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. - Google Patents

Nuevos analogos de la acronicina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Info

Publication number
ES2146722T3
ES2146722T3 ES95400314T ES95400314T ES2146722T3 ES 2146722 T3 ES2146722 T3 ES 2146722T3 ES 95400314 T ES95400314 T ES 95400314T ES 95400314 T ES95400314 T ES 95400314T ES 2146722 T3 ES2146722 T3 ES 2146722T3
Authority
ES
Spain
Prior art keywords
acronicin
contain
pharmaceutical compositions
preparation procedure
new analogs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95400314T
Other languages
English (en)
Inventor
Michel Koch
Francois Tillequin
Alexios-Leandros Skaltsounis
Yves Rolland
Alain Pierre
Ghanem Atassi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of ES2146722T3 publication Critical patent/ES2146722T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)

Abstract

COMPUESTOS DE FORMULA (I) EN LA QUE R3,R4, R5, R6, X E Y SON TALES COMO SE DEFINEN E LA DESCRIPCION.
ES95400314T 1994-02-17 1995-02-15 Nuevos analogos de la acronicina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. Expired - Lifetime ES2146722T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9401806A FR2716197B1 (fr) 1994-02-17 1994-02-17 Nouveaux analogues de l'acronycine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
ES2146722T3 true ES2146722T3 (es) 2000-08-16

Family

ID=9460176

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95400314T Expired - Lifetime ES2146722T3 (es) 1994-02-17 1995-02-15 Nuevos analogos de la acronicina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Country Status (17)

Country Link
US (1) US5567707A (es)
EP (1) EP0668281B1 (es)
JP (1) JP2675271B2 (es)
CN (1) CN1055926C (es)
AT (1) ATE191216T1 (es)
AU (1) AU680080B2 (es)
CA (1) CA2142560C (es)
DE (1) DE69515922T2 (es)
DK (1) DK0668281T3 (es)
ES (1) ES2146722T3 (es)
FI (1) FI118767B (es)
FR (1) FR2716197B1 (es)
GR (1) GR3033003T3 (es)
NO (1) NO308472B1 (es)
NZ (1) NZ270509A (es)
PT (1) PT668281E (es)
ZA (1) ZA951334B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6130161A (en) 1997-05-30 2000-10-10 International Business Machines Corporation Method of forming copper interconnections with enhanced electromigration resistance and reduced defect sensitivity
FR2772765B1 (fr) * 1997-12-19 2000-03-17 Adir Nouveaux derives de l'acronycine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2856687B1 (fr) * 2003-06-25 2005-09-16 Servier Lab Nouveaux derives de benzo[a]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2902792A1 (fr) * 2006-06-21 2007-12-28 Servier Lab Nouveaux derives cinnamates de tetrahydro-7h-pyrano(2,3-c)acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3624087A (en) * 1967-07-17 1971-11-30 Lilly Co Eli Synthesis of acronycine and related compounds
US3621041A (en) * 1968-07-05 1971-11-16 Lilly Co Eli Chromans
US3673163A (en) * 1970-06-16 1972-06-27 Lilly Co Eli Pharmacological preparation containing an acronycine-polyvinylprrolidone coprecipitate
US3657249A (en) * 1970-10-12 1972-04-18 Lilly Co Eli Synthesis of nordihydroacronycine and related compounds
US3715359A (en) * 1971-07-02 1973-02-06 Lilly Co Eli Hydroxylated acronycine
US3943137A (en) * 1973-07-09 1976-03-09 University Of Kansas Endowment Association Acronycine derivatives

Also Published As

Publication number Publication date
NO308472B1 (no) 2000-09-18
CA2142560A1 (fr) 1995-08-18
PT668281E (pt) 2000-07-31
FI118767B (fi) 2008-03-14
ZA951334B (en) 1995-10-23
CN1113490A (zh) 1995-12-20
NZ270509A (en) 1996-03-26
NO950574D0 (no) 1995-02-16
GR3033003T3 (en) 2000-07-31
DE69515922D1 (de) 2000-05-04
FR2716197B1 (fr) 1996-04-19
EP0668281A1 (fr) 1995-08-23
NO950574L (no) 1995-08-18
JP2675271B2 (ja) 1997-11-12
AU680080B2 (en) 1997-07-17
JPH07252257A (ja) 1995-10-03
EP0668281B1 (fr) 2000-03-29
DK0668281T3 (da) 2000-08-14
FI950681A0 (fi) 1995-02-15
CA2142560C (fr) 2002-04-09
FR2716197A1 (fr) 1995-08-18
FI950681L (fi) 1995-08-18
AU1228795A (en) 1995-08-24
ATE191216T1 (de) 2000-04-15
CN1055926C (zh) 2000-08-30
US5567707A (en) 1996-10-22
DE69515922T2 (de) 2000-11-02

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