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ES2128093T3 - Procedimiento enzimatico para la preparacion de esteres de acidos carboxilicos quirales alfa-terciarios. - Google Patents

Procedimiento enzimatico para la preparacion de esteres de acidos carboxilicos quirales alfa-terciarios.

Info

Publication number
ES2128093T3
ES2128093T3 ES95936341T ES95936341T ES2128093T3 ES 2128093 T3 ES2128093 T3 ES 2128093T3 ES 95936341 T ES95936341 T ES 95936341T ES 95936341 T ES95936341 T ES 95936341T ES 2128093 T3 ES2128093 T3 ES 2128093T3
Authority
ES
Spain
Prior art keywords
esters
preparation
alpha
carboxylic acids
chiral carboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95936341T
Other languages
English (en)
Inventor
Fateme Sima Sariaslani
Barry Stieglitz
Vincent G Witterholt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/457,891 external-priority patent/US5580783A/en
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Application granted granted Critical
Publication of ES2128093T3 publication Critical patent/ES2128093T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

ESTA INVENCION PROPORCIONA UN PROCEDIMIENTO PARA ENRIQUECIMIENTO DE ENANTIOMEROS DE ESTERES DE ACIDO CARBOXILICO {AL}-TERCIARIOS A PARTIR DE MEZCLAS DE ESTERES CORRESPONDIENTE UTILIZANDO UN BIOCATALIZADOR QUE COMPRENDE CELULAS MICROBICAS, O PREPARADOS DE ENZIMA PARCIAL O ALTAMENTE PURIFICADOS. LOS PRODUCTOS DE ESTER ENANTIOMERICOS SON UTILES COMO INTERMEDIARIOS PARA LA PREPARACION DE COMPUESTOS FARMACEUTICA Y AGRICOLAMENTE ACTIVOS.
ES95936341T 1994-10-12 1995-10-04 Procedimiento enzimatico para la preparacion de esteres de acidos carboxilicos quirales alfa-terciarios. Expired - Lifetime ES2128093T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32149694A 1994-10-12 1994-10-12
US08/457,891 US5580783A (en) 1994-10-12 1995-06-01 Enzymatic process for the preparation of chiral α-tertiary carboxylic acid esters

Publications (1)

Publication Number Publication Date
ES2128093T3 true ES2128093T3 (es) 1999-05-01

Family

ID=26982998

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95936341T Expired - Lifetime ES2128093T3 (es) 1994-10-12 1995-10-04 Procedimiento enzimatico para la preparacion de esteres de acidos carboxilicos quirales alfa-terciarios.

Country Status (10)

Country Link
EP (1) EP0786012B1 (es)
JP (1) JP3794702B2 (es)
CN (1) CN1160421A (es)
AU (1) AU3832995A (es)
CZ (1) CZ111197A3 (es)
DE (1) DE69506900T2 (es)
DK (1) DK0786012T3 (es)
ES (1) ES2128093T3 (es)
IL (1) IL115594A (es)
WO (1) WO1996012035A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2732679B1 (fr) * 1995-04-07 1997-04-30 Synthelabo Procede de preparation enzymatique d'un intermediaire de synthese de la befloxatone
NZ523554A (en) * 2000-07-13 2004-12-24 Sankyo Co Amino alcohol derivatives
DE602004028038D1 (de) * 2003-11-14 2010-08-19 Ucl Business Plc Immunmodulator mit ganzzell-tsukamurella bakterien
CN1948499B (zh) * 2006-05-26 2010-12-08 江南大学 生物催化制备(r)-4,4,4-三氟-3-羟基丁酸乙酯的方法
CN102719496B (zh) * 2012-06-21 2014-08-06 浙江工业大学 一种微生物转化苯甲酰甲酸乙酯制备(s)-(+)-扁桃酸乙酯的方法
CN103290072B (zh) * 2013-02-28 2014-10-22 南京工业大学 一种酶法不对称还原制备(s)-4-氯-3羟基丁酸乙酯的方法
CN104313064A (zh) * 2014-10-01 2015-01-28 青岛科技大学 一种细胞法生产手性溴苯基丙酸甲酯的方法
CN105838772A (zh) * 2016-05-27 2016-08-10 苏州汉酶生物技术有限公司 (s)-5-氯-2,3-二氢-2-羟基-1-氧代-1h-茚-2-羧酸甲酯的生物制备方法
CN105969815B (zh) * 2016-06-07 2021-02-26 苏州汉酶生物技术有限公司 一种(s)-5-氯-2,3-二氢-2-羟基-1-氧代-1h-茚-2-羧酸甲酯的生物制备方法
CN110527646B (zh) * 2019-08-20 2021-05-11 浙江工业大学 热带芽孢杆菌wzz018及其应用
CN112345663B (zh) * 2020-10-22 2022-10-21 京博农化科技有限公司 一种5-氯-2-甲氧羰基-1-茚酮酯含量的分析方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668628A (en) * 1985-04-01 1987-05-26 Stauffer Chemical Company Resolution of racemic mixtures of aliphatic acid esters
EP0197474B1 (en) * 1985-04-01 1991-07-10 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for preparing optically active indoline-2-carboxylic acid
FI95931C (fi) * 1988-09-02 1996-04-10 Tanabe Seiyaku Co Menetelmä (2R,3S)-3-(4-metoksifenyyli)glysidiinihapon alemman alkyyliesterin valmistamiseksi
US5202260A (en) * 1991-05-08 1993-04-13 Genzyme Corporation Resolution of α-tertiary carboxylic acid esters using lipase from Candida lipolytica
CA2068038A1 (en) * 1991-05-08 1992-11-09 Christopher Yee Enzymatic resolution of .alpha.-tertiary carboxylic acid esters

Also Published As

Publication number Publication date
IL115594A (en) 2000-01-31
JP3794702B2 (ja) 2006-07-12
CN1160421A (zh) 1997-09-24
JPH10507360A (ja) 1998-07-21
EP0786012A1 (en) 1997-07-30
DE69506900D1 (de) 1999-02-04
WO1996012035A1 (en) 1996-04-25
IL115594A0 (en) 1996-01-19
DK0786012T3 (da) 1999-08-23
DE69506900T2 (de) 1999-07-22
EP0786012B1 (en) 1998-12-23
CZ111197A3 (en) 1997-07-16
AU3832995A (en) 1996-05-06

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