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ES2118709T3 - Compuestos macrolidos. - Google Patents

Compuestos macrolidos.

Info

Publication number
ES2118709T3
ES2118709T3 ES89304672T ES89304672T ES2118709T3 ES 2118709 T3 ES2118709 T3 ES 2118709T3 ES 89304672 T ES89304672 T ES 89304672T ES 89304672 T ES89304672 T ES 89304672T ES 2118709 T3 ES2118709 T3 ES 2118709T3
Authority
ES
Spain
Prior art keywords
group
hydrogen atom
compounds
chem
defined above
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89304672T
Other languages
English (en)
Inventor
Gordon C Lawrence
Michael John Dawson
David Noble
Michael V J Ramsay
Richard Bell
Derek R Sutherland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ES2118709T3 publication Critical patent/ES2118709T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Molecular Biology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Furan Compounds (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

COMPUESTOS DE FORMULA (I) DONDE R REPRESENTA UN RESIDUO DE AZUCAR O UN DERIVADO ACETILADO DE ESTO; R EXP1 REPRESENTA UN METILO, ETILO O ISOPROPILO; Y EXP1 ES - CH2, Y (AL CUADRADO) ES - CH - Y X REPRESENTA (II), DONDE R (AL CUADRADO) REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO OR EXP6, (DONDE OR EXP6 ES UN GRUPO HIDROXILO O UN GRUPO HIDROXILO SUSTITUIDO CON HASTA 25 ATOMOS DE CARBONO) Y R EXP3 REPRESENTA UN ATOMO DE HIDROGENO, O R (AL CUADRADO) Y R EXP3 JUNTO CON EL ATOMO DE CARBONO AL QUE ESTAN UNIDOS REPRESENTAN > C = 0, > C = CH2 O > C = NOR EXP7, (DONDE R EXP7 REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO C1 - 8 ALQUILO O UN GRUPO C3 - 8 ALQUENILO) Y EL GRUPO > C = NOR EXP7 ESTA EN LA CONFIGURACION E); Y R EXP4 REPRESENTA UN GRUPO OR EXP6 COMO SE DEFINE ARRIBA Y R EXP5 REPRESENTA UN ATOMO DE HIDROGENO, O R EXP4 Y R EXP5 JUNTO CON LOS ATOMOS DE CARBONO AL QUE ESTAN UNIDOS REPRESENTAN > C = 0 O > C = NOR EXP8, Y SALES DE ESTO. LOS COMPUESTOS SON UTILES PARA CONTROLAR NEMATODOS, ACARINA, INSECTOS U OTRAS PLAGAS.
ES89304672T 1988-05-10 1989-05-09 Compuestos macrolidos. Expired - Lifetime ES2118709T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888811036A GB8811036D0 (en) 1988-05-10 1988-05-10 Chemical compounds

Publications (1)

Publication Number Publication Date
ES2118709T3 true ES2118709T3 (es) 1998-10-01

Family

ID=10636653

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89304672T Expired - Lifetime ES2118709T3 (es) 1988-05-10 1989-05-09 Compuestos macrolidos.

Country Status (17)

Country Link
US (1) US5116968A (es)
EP (1) EP0341973B1 (es)
JP (1) JPH0772192B2 (es)
KR (1) KR900018108A (es)
AT (1) ATE168691T1 (es)
AU (1) AU625416B2 (es)
BR (1) BR8902168A (es)
CA (1) CA1321965C (es)
DD (1) DD296929A5 (es)
DE (1) DE68928745T2 (es)
DK (1) DK170344B1 (es)
ES (1) ES2118709T3 (es)
GB (1) GB8811036D0 (es)
HU (1) HU206136B (es)
NZ (1) NZ229050A (es)
PT (1) PT90507B (es)
ZA (1) ZA893429B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8721371D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
US5015630A (en) * 1989-01-19 1991-05-14 Merck & Co., Inc. 5-oxime avermectin derivatives
NZ233680A (en) * 1989-05-17 1995-02-24 Beecham Group Plc Avermectins and milbemycins and compositions thereof
US5312753A (en) * 1992-03-23 1994-05-17 Merck & Co., Inc. Strain of streptomyces avermitilis capable of glycosylating avermectin compounds at the 13- and 14A positions
US6265202B1 (en) 1998-06-26 2001-07-24 Regents Of The University Of Minnesota DNA encoding methymycin and pikromycin
US20030194784A1 (en) * 2001-04-17 2003-10-16 Sherman David H. DNA encoding methymycin and pikromycin
US6764999B2 (en) * 2002-07-11 2004-07-20 Stephen E. Bachman Nasal delivery of parasiticides
CN102911227B (zh) * 2008-09-27 2015-08-12 上海市农药研究所 一种淀粉酶产色链霉菌、其发酵产物及应用
US10136886B2 (en) 2013-12-20 2018-11-27 Biomet Sports Medicine, Llc Knotless soft tissue devices and techniques
CN105994304B (zh) * 2016-05-09 2020-04-03 华东理工大学 一种昆虫细胞免疫抑制剂的用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
FI860233A7 (fi) * 1985-01-22 1986-07-23 Ciba Geigy Ag 13 -alkyyli-milbemysiinijohdannaiset eläin- ja kasviloisen torjuntaan.
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
JPH0678342B2 (ja) * 1986-01-07 1994-10-05 三共株式会社 新規マクロライド化合物
CA1301745C (en) * 1986-01-23 1992-05-26 Michael Vincent John Ramsay Macrolide antibiotics and their preparation
EP0238259B1 (en) * 1986-03-12 1993-09-29 American Cyanamid Company Macrolide compounds
GB8606108D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
US4849446A (en) * 1986-09-12 1989-07-18 American Cyanamid Company 23-imino derivatives of 23-keto compounds
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
DE3750355T2 (de) * 1986-09-12 1995-04-06 American Cyanamid Co 23-Oxo(keto) und 23-Imino-Derivate von LL-F28249-Verbindungen.
IN167980B (es) * 1987-01-23 1991-01-19 Pfizer
ES2058244T3 (es) * 1987-01-23 1994-11-01 Pfizer Procedimiento para produccion de avermectinas y cultivos para el mismo.
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives

Also Published As

Publication number Publication date
DD296929A5 (de) 1991-12-19
GB8811036D0 (en) 1988-06-15
DK227189A (da) 1989-11-11
DE68928745D1 (de) 1998-08-27
CA1321965C (en) 1993-09-07
JPH02218688A (ja) 1990-08-31
AU3456889A (en) 1989-12-14
EP0341973A2 (en) 1989-11-15
HUT54372A (en) 1991-02-28
JPH0772192B2 (ja) 1995-08-02
AU625416B2 (en) 1992-07-09
EP0341973A3 (en) 1991-01-30
DK170344B1 (da) 1995-08-07
PT90507A (pt) 1989-11-30
PT90507B (pt) 1994-08-31
NZ229050A (en) 1991-06-25
KR900018108A (ko) 1990-12-20
DE68928745T2 (de) 1998-12-10
EP0341973B1 (en) 1998-07-22
ATE168691T1 (de) 1998-08-15
BR8902168A (pt) 1990-01-02
ZA893429B (en) 1990-03-28
DK227189D0 (da) 1989-05-09
HU206136B (en) 1992-08-28
US5116968A (en) 1992-05-26

Similar Documents

Publication Publication Date Title
ES2118709T3 (es) Compuestos macrolidos.
AU6990987A (en) Macrolide compounds
GB8813150D0 (en) Chemical compounds
IE890259L (en) Macrolide compounds
DE68927070D1 (de) Makrolid-Derivate
PT88462A (pt) Process for the preparation of macrolide compounds and of compositions containing them
ATE133416T1 (de) Makrolid-derivate

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