ES2111083T3 - Composiciones que contienen antibioticos de quinolona y poli(sulfonato de estireno). - Google Patents
Composiciones que contienen antibioticos de quinolona y poli(sulfonato de estireno).Info
- Publication number
- ES2111083T3 ES2111083T3 ES92920802T ES92920802T ES2111083T3 ES 2111083 T3 ES2111083 T3 ES 2111083T3 ES 92920802 T ES92920802 T ES 92920802T ES 92920802 T ES92920802 T ES 92920802T ES 2111083 T3 ES2111083 T3 ES 2111083T3
- Authority
- ES
- Spain
- Prior art keywords
- compositions containing
- quinolones
- stirene
- sulphonate
- antibiotics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- JXLHNMVSKXFWAO-UHFFFAOYSA-N azane;7-fluoro-2,1,3-benzoxadiazole-4-sulfonic acid Chemical compound N.OS(=O)(=O)C1=CC=C(F)C2=NON=C12 JXLHNMVSKXFWAO-UHFFFAOYSA-N 0.000 title 1
- 150000007660 quinolones Chemical class 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920000172 poly(styrenesulfonic acid) Polymers 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 229940005642 polystyrene sulfonic acid Drugs 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
- 239000011885 synergistic combination Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
SE DESCRIBEN COMPOSICIONES FARMACEUTICAS ACUOSAS CONTENIENDO UNA COMBINACION SINERGICA DE UNA QUINOLONA Y UN POLIMERO ACIDO SULFONICO DE POLIESTIRENO, DONDE LAS COMPOSICIONES SON SOLUCIONES LIMPIAS QUE RESULTAN CONFORTABLES Y TIENEN LIBERACION SOSTENIDA. SE DESCRIBEN METODOS PARA USO DE LAS COMPOSICIONES. ESTE TIPO DE FORMULACION ES PARTICULARMENTE UTIL CON QUINOLONAS DEL TIPO DE CIPROFLOXACINA, AUMENTANDO CONSIDERABLEMENTE LA SOLUBILIDAD DE ESTAS QUINOLONAS, HACIENDO FACTIBLE PODER TENER SOLUCIONES ACUOSAS QUE CONTIENEN TALES QUINOLONAS EN, O CERCA DE, PH FISIOLOGICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76110491A | 1991-09-17 | 1991-09-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2111083T3 true ES2111083T3 (es) | 1998-03-01 |
Family
ID=25061139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92920802T Expired - Lifetime ES2111083T3 (es) | 1991-09-17 | 1992-09-11 | Composiciones que contienen antibioticos de quinolona y poli(sulfonato de estireno). |
Country Status (9)
Country | Link |
---|---|
US (1) | US5679336A (es) |
EP (1) | EP0604570B1 (es) |
AT (1) | ATE162081T1 (es) |
AU (1) | AU2672892A (es) |
DE (1) | DE69224071T2 (es) |
DK (1) | DK0604570T3 (es) |
ES (1) | ES2111083T3 (es) |
GR (1) | GR3026209T3 (es) |
WO (1) | WO1993005816A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2106680B1 (es) * | 1995-08-03 | 1998-07-01 | Vita Invest Sa | Composiciones acuosas conteniendo ciprofloxacino y utilizacion y procedimiento correspondientes. |
US5695882A (en) * | 1995-08-17 | 1997-12-09 | The University Of Montana | System for extracting soluble heavy metals from liquid solutions |
ID21415A (id) | 1997-12-05 | 1999-06-10 | Upjohn Co | Senyawa-senyawa antibiotik magnesium quinolon |
EP1800687A3 (en) * | 1999-05-13 | 2009-12-30 | Genzyme Corporation | Anionic polymers as toxin binders and antibacterial agents |
US6290946B1 (en) | 1999-05-13 | 2001-09-18 | Geltex Pharmaceuticals, Inc. | Anionic polymers as toxin binders and antibacterial agents |
US6270755B1 (en) * | 1999-05-13 | 2001-08-07 | Geltex Pharmaceuticals, Inc. | Anionic polymers as toxin binders |
ATE411047T1 (de) * | 1999-07-14 | 2008-10-15 | Schering Plough Ltd | Maskieren des geschmacks der oralen flüssigen chinolon-zubereitungen mit ionenaustauscherharzen |
US6514492B1 (en) | 1999-07-14 | 2003-02-04 | Schering-Plough Veterinary Corporation | Taste masking of oral quinolone liquid preparations using ion exchange resins |
AU776609B2 (en) | 1999-09-24 | 2004-09-16 | Novartis Ag | Topical suspension formulations containing ciprofloxacin and dexamethasone |
ES2199873T3 (es) * | 1999-11-01 | 2004-03-01 | Alcon Inc. | Composiciones farmaceuticas que contienen un farmaco antibiotico de fluoroquinolona y goma xantan. |
CA2314494A1 (en) | 2000-05-02 | 2001-11-02 | Geltex Pharmaceuticals, Inc. | Anionic polymers as species specific antibacterial agents |
DK1305033T3 (da) | 2000-07-28 | 2005-01-31 | Alcon Inc | Farmaceutiske pæaparater indeholdende tobramycin og xanthangummi |
US6743439B1 (en) * | 2001-06-27 | 2004-06-01 | Alcon, Inc. | Ophthalmic compositions containing copolymers of sulfonated styrene and maleic anhydride |
EP1429780B1 (en) | 2001-09-21 | 2005-12-21 | Alcon, Inc. | Method of treating middle ear infections |
JP2006151808A (ja) * | 2002-12-24 | 2006-06-15 | Dai Ichi Seiyaku Co Ltd | 抗菌性水性製剤 |
DE102006010643A1 (de) * | 2006-03-08 | 2007-09-13 | Bayer Healthcare Aktiengesellschaft | Arzneimittel enthaltend Fluorchinolone |
AU2010216348B2 (en) * | 2009-02-18 | 2015-01-22 | Aradigm Corporation | pH-modulated formulations for pulmonary delivery |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS53141286A (en) * | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
US4292317A (en) * | 1977-09-20 | 1981-09-29 | Laboratorie Roger Bellon | 1,4-Dihydro-quinoline-3-carboxylic acid derivatives, process for their preparation and compositions containing them |
JPS5746986A (en) * | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
US4670444B1 (en) * | 1980-09-03 | 1999-02-09 | Bayer Ag | and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds |
US4615882A (en) * | 1982-09-27 | 1986-10-07 | Stockel Richard F | Disinfectant solution for contact lens |
DE3719764A1 (de) * | 1987-06-13 | 1988-12-22 | Bayer Ag | Ionenaustauscherharze beladen mit chinoloncarbonsaeurederivaten, ihre herstellung und verwendung |
-
1992
- 1992-09-11 AT AT92920802T patent/ATE162081T1/de not_active IP Right Cessation
- 1992-09-11 DE DE69224071T patent/DE69224071T2/de not_active Expired - Fee Related
- 1992-09-11 DK DK92920802T patent/DK0604570T3/da active
- 1992-09-11 AU AU26728/92A patent/AU2672892A/en not_active Abandoned
- 1992-09-11 ES ES92920802T patent/ES2111083T3/es not_active Expired - Lifetime
- 1992-09-11 WO PCT/US1992/007744 patent/WO1993005816A1/en active IP Right Grant
- 1992-09-11 EP EP92920802A patent/EP0604570B1/en not_active Expired - Lifetime
-
1995
- 1995-10-18 US US08/544,624 patent/US5679336A/en not_active Expired - Fee Related
-
1998
- 1998-02-25 GR GR980400386T patent/GR3026209T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO1993005816A1 (en) | 1993-04-01 |
ATE162081T1 (de) | 1998-01-15 |
GR3026209T3 (en) | 1998-05-29 |
DE69224071D1 (de) | 1998-02-19 |
US5679336A (en) | 1997-10-21 |
EP0604570A1 (en) | 1994-07-06 |
EP0604570B1 (en) | 1998-01-14 |
AU2672892A (en) | 1993-04-27 |
DK0604570T3 (da) | 1998-09-14 |
DE69224071T2 (de) | 1998-05-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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