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ES2100900T3 - Procedimiento para la determinacion de un ion con sensibilidad aumentada, utilizacion de sustancias apropiadas para ello y agente correpondiente. - Google Patents

Procedimiento para la determinacion de un ion con sensibilidad aumentada, utilizacion de sustancias apropiadas para ello y agente correpondiente.

Info

Publication number
ES2100900T3
ES2100900T3 ES91107496T ES91107496T ES2100900T3 ES 2100900 T3 ES2100900 T3 ES 2100900T3 ES 91107496 T ES91107496 T ES 91107496T ES 91107496 T ES91107496 T ES 91107496T ES 2100900 T3 ES2100900 T3 ES 2100900T3
Authority
ES
Spain
Prior art keywords
group
radicals
halogen
ion
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91107496T
Other languages
English (en)
Inventor
Walter Rittersdorf
Werner Guethlein
Detlef Thym
Peter Vogel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2100900T3 publication Critical patent/ES2100900T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
    • C07C205/20—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/21—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups and hydroxy groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C205/24—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups and hydroxy groups bound to carbon atoms of the same non-condensed six-membered aromatic ring having three, and only three, nitro groups bound to the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/02—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides
    • C07C245/06—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings
    • C07C245/10—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/63—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C255/65—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton with the nitrogen atoms further bound to nitrogen atoms
    • C07C255/66—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton with the nitrogen atoms further bound to nitrogen atoms having cyano groups and nitrogen atoms being part of hydrazine or hydrazone groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24—Halogenated derivatives
    • C07C39/26—Halogenated derivatives monocyclic monohydroxylic containing halogen bound to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24—Halogenated derivatives
    • C07C39/26—Halogenated derivatives monocyclic monohydroxylic containing halogen bound to ring carbon atoms
    • C07C39/27—Halogenated derivatives monocyclic monohydroxylic containing halogen bound to ring carbon atoms all halogen atoms being bound to ring carbon atoms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

LA INVENCION CONSTA DE UN METODO PARA LA DETERMINACION DE UN ION EN UN LIQUIDO ACUOSO, DONDE EL ION LLEGA A UNA FASE NO MEZCLADA CON EL LIQUIDO ACUOSO Y ALLI, UN INDICADOR PH PRESENTE OBTIENE UN CAMBIO DE COLOR, LO QUE ATRAE A LA DETERMINACION DEL ION. ESTO SE CARACTERIZA POR EL GRAN AUMENTO DE SENSIBILIDAD DE FASE NO MEZCLADA EN LIQUIDO ACUOSO EN UNA SUSTANCIA DEL GRUPO DE LAS COMBINACIONES DE LA FORMULA GENERAL EN DONDE UNOS DE LOS RESTOS DE R ELEVADO 1 Y R ELEVADO 4 ES UN RESTO DEL GRUPO DE RESTOS DE ALQUILO, DE RESTOS DE ALCOXI Y DE RESTOS DE ARALQUILO Y LOS RESTANTES RESTOS SIGNIFICAN LO MISMO O DIFERENTES Y CADA UNO SON UN GRUPO DE NITRO, HALOGENO, UN GRUPO DE CIANO, UN GRUPO DE ALQUILSULFONILOL O UN GRUPO DE ALQUILO SUSTITUYENTE CON HALOGENO DE LA FORMULA GENERAL II EN DONDE UNO DE LOS RESTOS DE R ELEVADO 5 Y R ELEVADO 9 ES UN RESTO DE LOS GRUPOS DE RESTOS DE ALQUILO, RESTOS DE ALCOXI Y RESTOS DE ARALQUILO Y LOS SIGUIENTES RESTOS SON IGUALES O DIFERENTES Y CADA UNO SIGNIFICA UN GRUPODE NITRO, HALOGENO, UN GRUPO DE CIANO, UN GRUPO DE ALQUILOSULFONILO, O SUSTITUYENTES DE UN GRUPO DE ALQUILO CON HALOGENO O SI R ELEVADO 5 Y R ELEVADO 6 REPRESENTA GRUPOS DE NITRO, R ELEVADO 8 Y R ELEVADO 9 PUEDEN SIGNIFICAR TAMBIEN HIDROGENO Y DE LA FORMULA GENERAL III EN DONDE R ELEVADO 10, R ELEVADO 11, R ELEVADO 12, R ELEVADO 13, R ELEVADO 14 SON IGUALES O DIFERENTES Y CADA UNA SIGNIFICA HIDROGENO, UN GRUPO DE NITRO, HALOGENOS, UN GRUPO DE CIANO, UN GRUPO DE ALQUILOSULFONILO O SUSTITUYENTES DE UN GRUPO DE ALQUILO CON HALOGENO. SE EMPLEA PARA UNA COMBINACION ADECUADA Y PARA UN ADECUADO MEDIO CORRESPONDIENTE.
ES91107496T 1990-05-15 1991-05-08 Procedimiento para la determinacion de un ion con sensibilidad aumentada, utilizacion de sustancias apropiadas para ello y agente correpondiente. Expired - Lifetime ES2100900T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4015592A DE4015592A1 (de) 1990-05-15 1990-05-15 Verfahren zur bestimmung eines ions mit erhoehter empfindlichkeit, verwendung hierfuer geeigneter substanzen und entsprechendes mittel

Publications (1)

Publication Number Publication Date
ES2100900T3 true ES2100900T3 (es) 1997-07-01

Family

ID=6406464

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91107496T Expired - Lifetime ES2100900T3 (es) 1990-05-15 1991-05-08 Procedimiento para la determinacion de un ion con sensibilidad aumentada, utilizacion de sustancias apropiadas para ello y agente correpondiente.

Country Status (8)

Country Link
US (1) US5215924A (es)
EP (1) EP0457182B1 (es)
JP (1) JP2665412B2 (es)
AT (1) ATE149251T1 (es)
AU (1) AU627654B2 (es)
CA (1) CA2042416C (es)
DE (2) DE4015592A1 (es)
ES (1) ES2100900T3 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4116108A1 (de) * 1991-05-17 1992-11-19 Behringwerke Ag Reagenz zur bestimmung der ionenstaerke bzw. des spezifischen gewichtes von waessrigen fluessigkeiten und verfahren
US5565363A (en) * 1991-10-21 1996-10-15 Wako Pure Chemical Industries, Ltd. Reagent composition for measuring ionic strength or specific gravity of aqueous solution samples
US6165796A (en) * 1997-11-26 2000-12-26 Beckman Coulter, Inc. Pipettable ion detector and method
US20100145294A1 (en) * 2008-12-05 2010-06-10 Xuedong Song Three-dimensional vertical hydration/dehydration sensor
US20100159611A1 (en) * 2008-12-18 2010-06-24 Xuedong Song Hydration/dehydration sensor
CN108276305B (zh) * 2018-01-06 2020-07-31 江西理工大学 一种温和的制备苏丹红i结构类似物的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3800051A (en) * 1970-09-21 1974-03-26 Dow Chemical Co Reducing serum cholesterol with certain substituted phenols
JPS5112077B2 (es) * 1973-02-12 1976-04-15
JPS63204148A (ja) * 1987-02-20 1988-08-23 Konica Corp 多層分析素子
JPH0788332B2 (ja) * 1987-06-04 1995-09-27 住友化学工業株式会社 ２−アミノ−４，６−ジクロル−５−アルキルフェノ−ルの製造法
JPS6440448A (en) * 1987-08-06 1989-02-10 Ube Industries Benzyltrimethylammonium chlorobromate(1-) and bromination using said chlorobromate
JPS6447741A (en) * 1987-08-18 1989-02-22 Nippon Kayaku Kk Production of 2,4-dichloro-3-ethyl-6-nitrophenol
JPH01228943A (ja) * 1988-03-09 1989-09-12 Sumitomo Chem Co Ltd ２，４―ジクロロ―３―アルキル―６―ニトロフェノールの製造方法
JPH01258649A (ja) * 1988-04-05 1989-10-16 Sumitomo Chem Co Ltd ２，４−ジクロロ−３−アルキル−６−ニトロフェノールの製造方法
DE3817626A1 (de) * 1988-05-25 1989-11-30 Bayer Ag Fluorierte bis-aryloxy-substituierte alkene, verfahren zu deren herstellung und deren verwendung

Also Published As

Publication number Publication date
EP0457182A3 (en) 1992-12-02
DE59108562D1 (de) 1997-04-03
US5215924A (en) 1993-06-01
CA2042416C (en) 1999-10-05
JPH04231867A (ja) 1992-08-20
ATE149251T1 (de) 1997-03-15
EP0457182A2 (de) 1991-11-21
DE4015592A1 (de) 1991-11-21
AU7641591A (en) 1991-11-21
JP2665412B2 (ja) 1997-10-22
AU627654B2 (en) 1992-08-27
EP0457182B1 (de) 1997-02-26
CA2042416A1 (en) 1991-11-16

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