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ES2082927T3 - Derivados de (p-carbonilaminofenil)-sulfonil-nitrometano. - Google Patents

Derivados de (p-carbonilaminofenil)-sulfonil-nitrometano.

Info

Publication number
ES2082927T3
ES2082927T3 ES91307019T ES91307019T ES2082927T3 ES 2082927 T3 ES2082927 T3 ES 2082927T3 ES 91307019 T ES91307019 T ES 91307019T ES 91307019 T ES91307019 T ES 91307019T ES 2082927 T3 ES2082927 T3 ES 2082927T3
Authority
ES
Spain
Prior art keywords
derivatives
nitromethane
carbonylaminophenyl
sulfonyl
oxaminoide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91307019T
Other languages
English (en)
Inventor
David Robert Brittain
Steven Paul Brown
Anthony Loren Cooper
Jethro Lawrence Longridge
Jeffrey James Morris
John Preston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Application granted granted Critical
Publication of ES2082927T3 publication Critical patent/ES2082927T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/38—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
    • C07C317/40—Y being a hydrogen or a carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/38—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
    • C07C317/42—Y being a hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

LA INVENCION CONCIERNE A NUEVOS DERIVADOS (OXAMINOIDO-FENILSULFONIL) NITROMETANO Y SUS SALES FARMACEUTICAMENTE ACEPTABLES QUE SON INHIBIDORES DE LA REDUCTASA ALDOSA DE ENZIMA Y SON DE VALOR, POR EJEMPLO, EN EL TRATAMIENTO DE CIERTOS EFECTOS PERIFERICOS DE LA DIABETES Y LA GALACTOSEMIA. TAMBIEN SE DESCRIBEN COMPOSICIONES FARMACEUTICAS CONTENIENDO UNO DE LOS DERIVADOS Y PROCESOS PARA LA FABRICACION Y USO DE LOS DERIVADOS.-
ES91307019T 1990-08-02 1991-07-31 Derivados de (p-carbonilaminofenil)-sulfonil-nitrometano. Expired - Lifetime ES2082927T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909016984A GB9016984D0 (en) 1990-08-02 1990-08-02 Aniline derivatives

Publications (1)

Publication Number Publication Date
ES2082927T3 true ES2082927T3 (es) 1996-04-01

Family

ID=10680069

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91307019T Expired - Lifetime ES2082927T3 (es) 1990-08-02 1991-07-31 Derivados de (p-carbonilaminofenil)-sulfonil-nitrometano.

Country Status (18)

Country Link
US (2) US5110808A (es)
EP (1) EP0469889B1 (es)
JP (1) JPH04234355A (es)
AT (1) ATE133161T1 (es)
AU (1) AU647502B2 (es)
CA (1) CA2048345A1 (es)
DE (1) DE69116466T2 (es)
DK (1) DK0469889T3 (es)
ES (1) ES2082927T3 (es)
FI (1) FI97225C (es)
GB (1) GB9016984D0 (es)
GR (1) GR3018711T3 (es)
HU (1) HU211217B (es)
IE (1) IE72962B1 (es)
NO (1) NO175252C (es)
NZ (1) NZ239125A (es)
PT (1) PT98530B (es)
ZA (1) ZA915747B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4201699A1 (de) * 1992-01-23 1993-07-29 Basf Ag Gemischte oxalsaeurediamide
EP0662962A1 (en) * 1992-09-28 1995-07-19 Pfizer Inc. Substituted pyrimidines for control of diabetic complications
AU7958194A (en) * 1994-09-23 1996-04-09 Smithkline Beecham Corporation Human galactokinase gene
FR2757509B1 (fr) * 1996-12-23 1999-03-26 Lipha Nouveaux derives de sulfonamides et sulfonylurees, leurs preparations et medicaments les contenant
FR2829766A1 (fr) * 2001-09-14 2003-03-21 Lipha Derives d'oxamates comportant un heterocycle azote diversement substitue
WO2012077221A1 (ja) * 2010-12-10 2012-06-14 アグロカネショウ株式会社 ３-アミノオキサリルアミノベンズアミド誘導体及びこれを有効成分とする殺虫、殺ダニ剤
WO2018232317A1 (en) * 2017-06-16 2018-12-20 University Of Utah Research Foundation Methods and compositions for treatment or prevention of symptoms of classic galactosemia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3326663A (en) * 1964-09-25 1967-06-20 Shell Oil Co Herbicidal phenylureas
DE1518824A1 (de) * 1965-05-03 1969-01-23 Hoechst Ag Sulfonylarylharnstoffe und Verfahren zu ihrer Herstellung
US4412024A (en) * 1981-09-14 1983-10-25 Sandoz Ltd. Concentrated solutions of aromatic oxamide stabilizers
GB8718619D0 (en) * 1987-08-06 1987-09-09 Ici Plc Pharmaceutical compositions
GB8902409D0 (en) * 1989-02-03 1989-03-22 Ici Plc Aliphatic compounds
GB9016978D0 (en) * 1990-08-02 1990-09-19 Ici Plc Acetamide derivatives

Also Published As

Publication number Publication date
PT98530B (pt) 1999-01-29
ZA915747B (en) 1992-05-27
US5110808A (en) 1992-05-05
FI913707L (fi) 1992-02-03
DE69116466D1 (de) 1996-02-29
JPH04234355A (ja) 1992-08-24
NZ239125A (en) 1993-11-25
HU912483D0 (en) 1991-12-30
ATE133161T1 (de) 1996-02-15
EP0469889B1 (en) 1996-01-17
NO913009L (no) 1992-02-03
NO913009D0 (no) 1991-08-01
FI97225B (fi) 1996-07-31
HU211217B (en) 1995-11-28
DK0469889T3 (da) 1996-06-10
GR3018711T3 (en) 1996-04-30
GB9016984D0 (en) 1990-09-19
DE69116466T2 (de) 1996-06-20
AU647502B2 (en) 1994-03-24
EP0469889A1 (en) 1992-02-05
AU8124591A (en) 1992-02-06
IE912554A1 (en) 1992-02-12
US5189031A (en) 1993-02-23
FI913707A0 (fi) 1991-08-02
NO175252C (no) 1994-09-21
FI97225C (fi) 1996-11-11
HUT59089A (en) 1992-04-28
CA2048345A1 (en) 1992-02-03
PT98530A (pt) 1992-06-30
NO175252B (no) 1994-06-13
IE72962B1 (en) 1997-05-07

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