[go: up one dir, main page]

ES2082775T3 - Anticuerpos de proteinas latentes de papilomavirus humano, sistemas de diagnostico y procedimientos. - Google Patents

Anticuerpos de proteinas latentes de papilomavirus humano, sistemas de diagnostico y procedimientos.

Info

Publication number
ES2082775T3
ES2082775T3 ES89304874T ES89304874T ES2082775T3 ES 2082775 T3 ES2082775 T3 ES 2082775T3 ES 89304874 T ES89304874 T ES 89304874T ES 89304874 T ES89304874 T ES 89304874T ES 2082775 T3 ES2082775 T3 ES 2082775T3
Authority
ES
Spain
Prior art keywords
antibodies
proteins
procedures
diagnostic systems
latent human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89304874T
Other languages
English (en)
Other versions
ES2082775T4 (es
Inventor
Joakim Dillner
Richard A Lerner
Richard Smith
D Elliot Parks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Publication of ES2082775T3 publication Critical patent/ES2082775T3/es
Application granted granted Critical
Publication of ES2082775T4 publication Critical patent/ES2082775T4/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/084—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

LA INVENCION SE REFIERE A POLIPEPTIDOS QUE INMUNOLOGICAMENTE IMITAN A PROTEINAS LATENTES DEL VIRUS DE PAPILOMA Y A ANTICUERPOS Y ANTICUERPOS MONOCLONALES QUE INMUNORREACCIONAN CON LAS CITADAS PROTEINAS LATENTES. TAMBIEN SE REFIERE A SISTEMAS Y METODOS PARA DETECTAR LA PRESENCIA Y TIPO DE PAPILOMAVIRUS EN UN SUJETO HUMANO.
ES89304874T 1988-05-16 1989-05-15 Anticuerpos de proteinas latentes de papilomavirus humano, sistemas de diagnostico y procedimientos. Expired - Lifetime ES2082775T4 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19440788A 1988-05-16 1988-05-16
US07/323,614 US5180806A (en) 1988-05-16 1989-03-13 Polypeptides and compositions of human papillomavirus latent proteins, diagnostic systems and methods

Publications (2)

Publication Number Publication Date
ES2082775T3 true ES2082775T3 (es) 1996-04-01
ES2082775T4 ES2082775T4 (es) 1996-08-01

Family

ID=26889974

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89304874T Expired - Lifetime ES2082775T4 (es) 1988-05-16 1989-05-15 Anticuerpos de proteinas latentes de papilomavirus humano, sistemas de diagnostico y procedimientos.

Country Status (10)

Country Link
US (3) US5180806A (es)
EP (1) EP0344940B1 (es)
JP (1) JP2918904B2 (es)
AT (1) ATE130855T1 (es)
CA (1) CA1341287C (es)
DE (1) DE68924928T2 (es)
DK (1) DK173264B1 (es)
ES (1) ES2082775T4 (es)
GR (1) GR3018773T3 (es)
PT (1) PT90574B (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9001705D0 (sv) * 1990-05-11 1990-05-11 Medscand Ab Saett foer diagnostik av virusbaerande tumoerer genom immunoassay
US5932412A (en) * 1990-05-11 1999-08-03 Euro-Diagnostica Ab Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes
DE69223844T2 (de) * 1991-04-24 1998-04-16 Morinaga Milk Industry Co Ltd Antimikrobielles Peptid und antimikrobieller Wirkstoff
DK0523391T3 (da) * 1991-07-13 2003-06-23 Dade Behring Marburg Gmbh Anvendelse af HPV-16 E6 og E7 genafledte peptider til diagnostisk formål
DE4123760C2 (de) 1991-07-18 2000-01-20 Dade Behring Marburg Gmbh Seroreaktive Bereiche auf den HPV 16 Proteinen E1 und E2
US5437951A (en) * 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
GB9306731D0 (en) * 1993-03-31 1993-05-26 Cancer Res Campaign Tech Vaccines
DE19819476C1 (de) * 1998-04-30 2000-01-05 Deutsches Krebsforsch Polypeptid mit immunogenen Eigenschaften und veränderten biologischen Funktionen eines Proteins
GB2353581B (en) 1999-08-27 2003-06-11 Uponor Ltd Swage lining
US7026443B1 (en) * 1999-12-10 2006-04-11 Epimmune Inc. Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions
JP2001172200A (ja) * 1999-12-17 2001-06-26 Meneki Seibutsu Kenkyusho:Kk ヒトナプシンａに対する抗体およびこれを用いる医薬
CN1433428A (zh) * 2000-04-05 2003-07-30 冲击诊断公司 辨别人乳头瘤病毒的免疫学方法
AU2002219711B8 (en) * 2000-12-08 2006-03-02 Academisch Ziekenhuis Leiden Long peptides of 22-45 amino acid residues that induce and/or enhance antigen specific immune responses
EP1288292A1 (en) * 2001-08-31 2003-03-05 Leids Universitair Medisch Centrum Long peptides of 22-40 amino acid residues that induce and/or enhance antigen specific immune responses.
AU2002232722A1 (en) * 2000-12-21 2002-07-01 Biosignature Diagnostics, Inc. Absorbance multiplex technology
US6933123B2 (en) 2001-04-05 2005-08-23 Yao Xiong Hu Peptides from the E2, E6, and E7 proteins of human papilloma viruses 16 and 18 for detecting and/or diagnosing cervical and other human papillomavirus associated cancers
GB2379220A (en) * 2001-08-13 2003-03-05 Univ York Antibodies to HPV E2 protein
CN1846000B (zh) * 2003-09-05 2012-10-03 金克克国际有限公司 Hpv cd8+t细胞表位
US7399467B2 (en) * 2003-12-23 2008-07-15 Arbor Vita Corporation Antibodies for oncogenic strains of HPV and methods of their use
WO2005089164A2 (en) * 2003-12-31 2005-09-29 Pharmexa Inc. Inducing cellular immune responses to human papillomavirus using peptide and nucleic acid compositions
US7972776B2 (en) * 2005-11-15 2011-07-05 Oncohealth Corporation Protein chips for HPV detection
US7732166B2 (en) * 2005-11-15 2010-06-08 Oncohealth Corporation Detection method for human pappilomavirus (HPV) and its application in cervical cancer
US8051950B2 (en) * 2006-08-03 2011-11-08 Glacier Bay, Inc. System for reducing acoustic energy
US8968995B2 (en) * 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
US20100003704A1 (en) * 2008-06-13 2010-01-07 Shuling Cheng IN SITU detection of early stages and late stages HPV infection
US9562075B2 (en) * 2007-05-31 2017-02-07 Academisch Ziekenhuis Leiden H.O.D.N. Lumc Intradermal HPV peptide vaccination
JP2012526286A (ja) 2009-05-07 2012-10-25 オンコヘルス コーポレーション ヒトパピローマウイルス（ｈｐｖ）およびｈｐｖ関連癌の初期段階および後期段階の検出、スクリーニング、および診断のための高度または≧ｃｉｎ２の同定
CN107617110A (zh) * 2009-08-26 2018-01-23 西莱克塔生物科技公司 诱导t细胞辅助的组合物
CN102822672B (zh) 2010-01-08 2015-12-09 安科健康公司 用于诊断和筛选与hpv有关的癌症的高通量细胞基hpv免疫测定
WO2011085231A2 (en) * 2010-01-08 2011-07-14 Selecta Biosciences, Inc. Synthetic virus-like particles conjugated to human papillomavirus capsid peptides for use as vaccines
CN103940993A (zh) * 2013-01-23 2014-07-23 艾托金生物医药（苏州）有限公司 用于检测抗人乳头瘤病毒抗体的抗原及试剂盒和应用
SG11201912240QA (en) 2017-06-28 2020-01-30 Regeneron Pharma Anti-human papillomavirus (hpv) antigen-binding proteins and methods of use thereof
AU2019213286A1 (en) * 2018-01-24 2020-07-30 The Council Of The Queensland Institute Of Medical Research HPV immunotherapy
WO2020028532A1 (en) 2018-08-02 2020-02-06 The Board Of Regents Of The University Of Texas System Adjuvant effect of the tlr1/2 agonist diprovocim synergizes with checkpoint-inhibiting antibodies to eliminate disease
AU2021242300A1 (en) 2020-03-26 2022-10-13 Provectus Pharmatech, Inc. Novel uses of halogenated xanthenes in oncology and virology
US11938182B2 (en) 2020-03-26 2024-03-26 Provectus Pharmatech, Inc. Halogenated xanthenes as vaccine adjuvants
CN112920267B (zh) * 2021-03-09 2021-08-13 北京康乐卫士生物技术股份有限公司 一种抗人乳头瘤病毒31型的单克隆中和抗体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748109A (en) * 1983-07-01 1988-05-31 Baird Phillip J Assay method and reagent to determine antibodies to papillomavirus virions
LU85462A1 (fr) * 1984-07-11 1986-02-12 Univ Louvain Nouvelles compositions polymeres,procedes pour leur production et leurs applications
US4777239A (en) * 1986-07-10 1988-10-11 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic peptides of human papilloma virus

Also Published As

Publication number Publication date
PT90574A (pt) 1989-11-30
DK173264B1 (da) 2000-05-29
JPH0296593A (ja) 1990-04-09
GR3018773T3 (en) 1996-04-30
DE68924928D1 (de) 1996-01-11
US5401627A (en) 1995-03-28
CA1341287C (en) 2001-08-28
DK234789A (da) 1989-11-17
ES2082775T4 (es) 1996-08-01
US5486453A (en) 1996-01-23
EP0344940B1 (en) 1995-11-29
JP2918904B2 (ja) 1999-07-12
PT90574B (pt) 1994-09-30
US5180806A (en) 1993-01-19
EP0344940A3 (en) 1991-11-13
DK234789D0 (da) 1989-05-12
DE68924928T2 (de) 1996-10-17
ATE130855T1 (de) 1995-12-15
EP0344940A2 (en) 1989-12-06

Similar Documents

Publication Publication Date Title
ES2082775T3 (es) Anticuerpos de proteinas latentes de papilomavirus humano, sistemas de diagnostico y procedimientos.
DE59010787D1 (de) Erythropoietin (EPO)-Peptide und dagegen gerichtete Antikörper
IT1083606B (it) Contenitore particolarmente provetta per analisi o procedure immuno chomiche ed enzimatiche e procedimento per la sua fabbricazione
ATE177754T1 (de) Fragmente von prion proteinen.
FI882173A7 (fi) Synteettinen peptidiantigeeni HIV-2-tartunnan toteamiseksi.
EP0314402A3 (en) Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
DE3584035D1 (de) Nachweis von menschlichem cytomegalovirus-spezifischem igm.
DE3689948D1 (de) Monoklonale antikörper und testverfahren.
DE3887053D1 (de) Stlv-iii-verwandte polypeptide, diagnosesysteme und testmethoden.
DE3482924D1 (de) Reagenz zur verwendung im nachweis des antikoerpers gegen menschliche t-zellen-leukemievirusantigene.
DE68903882D1 (de) Immunochemisches testverfahren fuer humanen granulozyten-makrophagen-kolonie stimulierenden faktor.
ATE153770T1 (de) Künstliche standard- und kontrollseren zur verwendung in verfahren zur bestimmung von antikörpern
DE3650635D1 (de) Monoklonale Antikörper
DE3785175D1 (de) A-assoziierte h-antigene, spezifische monoklonale antikoerper und methoden zu deren verwendung zur blutgruppenbestimmung.
ATE60445T1 (de) Verfahren und testelement zum auffinden von zellaesionen.
DK116487A (da) Fremgangsmaade til eksponering af en epitop i et protein med bestemt polypeptidstruktur, samt vektorer til brug ved fremgangsmaaden, hybridproteiner omfattende epitopen, og anvendelse af hybridproteinet ved diagnoser.
ATE114818T1 (de) Immuntest zum nachweis von alpha-haloacetamiden.
DE3886032D1 (de) Hiv-1-verwandte polypeptide, diagnosesysteme und testverfahren.
FI891417A7 (fi) Apparat foer utfoerande av ett diagnostiskt test.
DK630189D0 (da) Fremgangsmaade og diagnosesaet til paavisning af antistoffer samt vandig vaskevaeske til brug herved
NO900048D0 (no) Paavisningsmetoder med individ-spesifikke antistoff.
NO890775D0 (no) Apparat for testing av utblaasningssikring.
DE59203874D1 (de) Schizosaccharomyces-spezifische Polypeptide.
ATE97915T1 (de) Hiv-1-verwandte polypeptide, diagnosesysteme und testverfahren.
ATE69056T1 (de) Tgf-polypeptide, davon derivierte antigene oligopeptide, davon erhaltene antikoerper.