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ES2073006T5 - Compuestos formadores de complejos unidos a polimeros y cascada, sus complejos y conjugados, procedimiento para su preparacion y agentes farmaceuticos que los contienen. - Google Patents

Compuestos formadores de complejos unidos a polimeros y cascada, sus complejos y conjugados, procedimiento para su preparacion y agentes farmaceuticos que los contienen.

Info

Publication number
ES2073006T5
ES2073006T5 ES90730017T ES90730017T ES2073006T5 ES 2073006 T5 ES2073006 T5 ES 2073006T5 ES 90730017 T ES90730017 T ES 90730017T ES 90730017 T ES90730017 T ES 90730017T ES 2073006 T5 ES2073006 T5 ES 2073006T5
Authority
ES
Spain
Prior art keywords
complexes
formers
waterfall
conjugates
polymers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90730017T
Other languages
English (en)
Other versions
ES2073006T3 (es
Inventor
Johannes Dr Platzek
Heribert Dr Schmitt-Willich
Heinz Dr Gries
Gabriele D Schuhmann-Giampieri
Hubert Dr Vogler
Hanns-Joachim Dr Weinmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6394147&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2073006(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2073006T3 publication Critical patent/ES2073006T3/es
Publication of ES2073006T5 publication Critical patent/ES2073006T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G85/00—General processes for preparing compounds provided for in this subclass
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/124—Macromolecular compounds dendrimers, dendrons, hyperbranched compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/06—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules
    • A61K51/065—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules conjugates with carriers being macromolecules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Steroid Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

LOS POLIMEROS EN CASCADA QUE CONTIENEN LIGANDO FORMADORES DE COMPLEJOS, EVENTUALMENTE CINCO IONES, COMO MINIMO, DE UN ELEMENTO DE LOS NUMEROS DE ORDEN 21 A 29, 39, 42, 44 O 57 HASTA 83, ASI COMO EVENTUALMENTE CATIONES INORGANICOS Y/O BASES INORGANICAS, AMINOACIDOS O AMIDAS DE AMINOACIDOS, SON VALIOSOS FORMADORES DE COMPLEJOS Y COMPLEJOS PARA UTILIZAR EN DIAGNOSTICOS Y TERAPEUTICA.
ES90730017T 1989-11-21 1990-11-19 Compuestos formadores de complejos unidos a polimeros y cascada, sus complejos y conjugados, procedimiento para su preparacion y agentes farmaceuticos que los contienen. Expired - Lifetime ES2073006T5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3938992A DE3938992A1 (de) 1989-11-21 1989-11-21 Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel

Publications (2)

Publication Number Publication Date
ES2073006T3 ES2073006T3 (es) 1995-08-01
ES2073006T5 true ES2073006T5 (es) 2000-01-16

Family

ID=6394147

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90730017T Expired - Lifetime ES2073006T5 (es) 1989-11-21 1990-11-19 Compuestos formadores de complejos unidos a polimeros y cascada, sus complejos y conjugados, procedimiento para su preparacion y agentes farmaceuticos que los contienen.

Country Status (19)

Country Link
US (10) US5364614A (es)
EP (1) EP0430863B2 (es)
JP (2) JP3179092B2 (es)
KR (1) KR100202796B1 (es)
AT (1) ATE122698T1 (es)
AU (1) AU684453C (es)
CA (1) CA2030472C (es)
DE (2) DE3938992A1 (es)
DK (1) DK0430863T4 (es)
ES (1) ES2073006T5 (es)
FI (1) FI107931B (es)
GR (1) GR3031629T3 (es)
HU (1) HUT56121A (es)
IE (1) IE69317B1 (es)
IL (1) IL96434A (es)
NO (1) NO178032C (es)
NZ (1) NZ236162A (es)
PT (1) PT95944B (es)
ZA (1) ZA909352B (es)

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US6299859B1 (en) 2001-10-09
KR100202796B1 (ko) 1999-06-15
IL96434A (en) 1995-01-24
EP0430863A2 (de) 1991-06-05
FI107931B (fi) 2001-10-31
FI905744L (fi) 1991-05-22
DK0430863T3 (da) 1995-07-10
IE904199A1 (en) 1991-05-22
CA2030472A1 (en) 1991-05-22
EP0430863B2 (de) 1999-08-25
CA2030472C (en) 2003-06-10
US6183724B1 (en) 2001-02-06
FI905744A0 (fi) 1990-11-21
IE69317B1 (en) 1996-09-04
US20050118105A1 (en) 2005-06-02
US5364614A (en) 1994-11-15
NO178032B (no) 1995-10-02
HUT56121A (en) 1991-07-29
AU684453C (en) 2001-08-02
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JP3179092B2 (ja) 2001-06-25
JP2000355593A (ja) 2000-12-26
US5911971A (en) 1999-06-15
US7208139B2 (en) 2007-04-24
PT95944A (pt) 1991-09-13
US6576222B2 (en) 2003-06-10
KR910009786A (ko) 1991-06-28
US6193950B1 (en) 2001-02-27
DE59009093D1 (de) 1995-06-22
US6054117A (en) 2000-04-25
EP0430863A3 (en) 1992-03-04
NZ236162A (en) 1993-03-26
NO905037L (no) 1991-05-22
DE3938992A1 (de) 1991-05-23
EP0430863B1 (de) 1995-05-17
PT95944B (pt) 1999-12-31
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AU684453B2 (en) 1997-12-18
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US5650136A (en) 1997-07-22
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JPH03246234A (ja) 1991-11-01
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ZA909352B (en) 1991-12-24
ATE122698T1 (de) 1995-06-15
US20020068037A1 (en) 2002-06-06
US6855309B2 (en) 2005-02-15
ES2073006T3 (es) 1995-08-01
US20030232017A1 (en) 2003-12-18
NO178032C (no) 1996-01-10

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