[go: up one dir, main page]

ES2059594T3 - Peptidos con actividad inhibidora de sistemas enzimaticos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. - Google Patents

Peptidos con actividad inhibidora de sistemas enzimaticos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.

Info

Publication number
ES2059594T3
ES2059594T3 ES89104007T ES89104007T ES2059594T3 ES 2059594 T3 ES2059594 T3 ES 2059594T3 ES 89104007 T ES89104007 T ES 89104007T ES 89104007 T ES89104007 T ES 89104007T ES 2059594 T3 ES2059594 T3 ES 2059594T3
Authority
ES
Spain
Prior art keywords
contain
preparation
pharmaceutical compositions
peptides
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89104007T
Other languages
English (en)
Inventor
Dario Chiarino
Angelo Carenzi
Bella Davide Della
Franco Pellacini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon Group SpA
Zambon SpA
Original Assignee
Zambon Group SpA
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group SpA, Zambon SpA filed Critical Zambon Group SpA
Application granted granted Critical
Publication of ES2059594T3 publication Critical patent/ES2059594T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/32Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE PRESENTAN COMPUESTOS DE LA FORMULA I, EN LA QUE R1, R2, R3, R4 Y N TIENEN LOS SIGNIFICADOS EXPLICADOS EN LAS ESPECIFICACIONES, TAMBIEN SE PRESENTA EL PROCESO PARA SU PREPARACION Y LAS COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN COMO INGREDIENTES ACTIVOS, LOS COMPUESTOS DE LA FORMULA I SON INHIBIDORES EN LOS SISTEMAS ENZIMATICOS Y SON UTILES EN EL CAMPO FARMACEUTICO.
ES89104007T 1988-03-16 1989-03-07 Peptidos con actividad inhibidora de sistemas enzimaticos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. Expired - Lifetime ES2059594T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8819790A IT1216103B (it) 1988-03-16 1988-03-16 Peptidi ad attivita' farmaceutica.

Publications (1)

Publication Number Publication Date
ES2059594T3 true ES2059594T3 (es) 1994-11-16

Family

ID=11161236

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89104007T Expired - Lifetime ES2059594T3 (es) 1988-03-16 1989-03-07 Peptidos con actividad inhibidora de sistemas enzimaticos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.

Country Status (12)

Country Link
US (1) US5028626A (es)
EP (1) EP0332999B1 (es)
JP (1) JPH024767A (es)
AT (1) ATE95169T1 (es)
AU (1) AU611269B2 (es)
CA (1) CA1325695C (es)
DE (1) DE68909451T2 (es)
ES (1) ES2059594T3 (es)
IE (1) IE890747L (es)
IL (1) IL89537A (es)
IT (1) IT1216103B (es)
ZA (1) ZA891784B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1216104B (it) * 1988-03-16 1990-02-22 Zambon Spa Peptidi ad attivita' farmaceutica.
ES2052454B1 (es) * 1992-12-31 1995-01-16 Zambon S A Dipeptidos y composiciones que los contienen con accion farmaceutica contra el envejecimiento.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2393788A2 (fr) * 1977-06-10 1979-01-05 Microbial Chem Res Found Derives de bestatine
JPS6026099B2 (ja) * 1977-09-21 1985-06-21 財団法人微生物化学研究会 ペプチド、その酸附加塩およびその製造法
JPS58121259A (ja) * 1982-01-09 1983-07-19 Microbial Chem Res Found ベスタチン新規誘導体
US4883808A (en) * 1987-08-27 1989-11-28 American Biotechnology Company Condensation products of cyclic diketones and ascorbic acid as immunomodulatory agents

Also Published As

Publication number Publication date
ATE95169T1 (de) 1993-10-15
ZA891784B (en) 1989-11-29
DE68909451T2 (de) 1994-02-10
IL89537A0 (en) 1989-09-10
AU611269B2 (en) 1991-06-06
AU3138489A (en) 1989-09-21
CA1325695C (en) 1993-12-28
IL89537A (en) 1993-06-10
DE68909451D1 (de) 1993-11-04
EP0332999A2 (en) 1989-09-20
IT8819790A0 (it) 1988-03-16
JPH024767A (ja) 1990-01-09
EP0332999A3 (en) 1990-11-28
IT1216103B (it) 1990-02-22
IE890747L (en) 1989-09-16
EP0332999B1 (en) 1993-09-29
US5028626A (en) 1991-07-02

Similar Documents

Publication Publication Date Title
ECSP941104A (es) Derivados de 2,6 diaminopurina, procedimiento para su preparacion y composiciones farmaceuticas que los contienen
ES2084944T3 (es) Amidas terapeuticas.
ES2161291T3 (es) N-(indol-2-carbonil)amidas y derivados como inhibidores de la glucogeno fosforilasa.
AR005703A1 (es) Oxazolidinonas sustituidas, procedimiento para su preparacion, uso de las mismas para preparar medicamentos y medicamentos que las contienen
MX9207449A (es) Inhibidores de la enzima proteolitica derivada de sacarina.
NO971889L (no) Forbindelser og sammensetninger for levering av aktive midler
AR001020A1 (es) Derivados de fenildicetona, procedimientos para prepararlos, las composiciones herbicidas que los contienen y el procedimiento para combatir elcrecimiento de las plantas indeseables con dichos derivados.
ES2052603T3 (es) Derivados de bencimidazol, procedimiento para su produccion y composicion farmaceutica que los contienen.
MX9308013A (es) 4-fenil-piridonas y 4-fenil-2-fenil-2-alcoxipiridinas sustituidas, procedimiento para su preparacion y medicamentos que los contienen.
ES2135429T3 (es) Derivados de ciclohexano sustituidos para el tratamiento de enfermedades.
ES2058228T3 (es) Compuestos activos sobre el sistema cardiovascular.
ES2054904T3 (es) Procedimiento para la preparacion de peptidos con actividad inhibidora de sistemas enzimaticos.
ES2171743T3 (es) Derivados de amidinas e isotioureas como inhibidores de la enzima sintasa de oxido nitrico.
ES2145234T3 (es) Derivados de la diosmetina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ES2059594T3 (es) Peptidos con actividad inhibidora de sistemas enzimaticos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
ES2132283T3 (es) Derivados n-heteroaril sustituidos de propanamida utiles en el tratamiento de enfermedades cardiovasculares.
ES2133918T3 (es) Nuevos esteroides seco-d activos en el sistema cardiovascular y composiciones farmaceuticas que los contienen.
DE69402004D1 (de) Beta-mercapto-propanamidderivate verwendbar zur Behandlung kardiovaskularer Krankheiten oder Erkrankungen
ES2095431T3 (es) N-(isoquinolein-5-il)-sulfonil-azacicloalcanos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ES2162986T3 (es) Derivados de mercapto-alcanoil-dipeptidos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ES2054790T3 (es) Compuestos que tienen actividad cardiovascular.
ES8200871A1 (es) Procedimiento para la obtencion de derivados de 2-amino-3,4-dihidropiridina
ES2147825T3 (es) Derivados tetraciclicos de la 1,4-oxazina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ES2087178T3 (es) Disulfato de ws7622a, procedimiento para su preparacion y su uso.
ES2162022T3 (es) Derivados de tiol con actividad inhibidora de la metalopeptidasa.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 332999

Country of ref document: ES