ES2046270T3 - Un procedimiento para fabricar una composicion farmaceutica en forma de una tableta de compresion multiple. - Google Patents
Un procedimiento para fabricar una composicion farmaceutica en forma de una tableta de compresion multiple.Info
- Publication number
- ES2046270T3 ES2046270T3 ES198888116540T ES88116540T ES2046270T3 ES 2046270 T3 ES2046270 T3 ES 2046270T3 ES 198888116540 T ES198888116540 T ES 198888116540T ES 88116540 T ES88116540 T ES 88116540T ES 2046270 T3 ES2046270 T3 ES 2046270T3
- Authority
- ES
- Spain
- Prior art keywords
- formulation
- pharmaceutical composition
- multiple compression
- procedure
- manufacturing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
COMPOSICION FARMACEUTICA EN FORMA DE COMPRIMIDOS POR COMPRESION MULTIPLE QUE COMPRENDE: A) UNA ZONA DISCRETA HECHA CON UNA FORMULACION A QUE CONTIENE UN MATERIAL BASE COMO VEHICULO COMBINADO CON UNA CANTIDAD DE DESCONGESTIVO TERAPEUTICAMENTE EFICAZ DE UN SIMPATOMIMETICO, O UNA SAL SUYA FARMACEUTICAMENTE ACEPTABLE, SIENDO EL VEHICULO UNA MEZCLA DE UNO O MAS ETERES CELULOSICOS EN CANTIDAD ENTRE 18 Y 50% EN PESO CON RESPECTO A LA FORMULACION A, DE 2 A 20% DE UNO O MAS TENSIOACTIVOS ANIONICOS FARMACEUTICAMENTE ACEPTABLES Y UNO O MAS EXCIPIENTES, Y B) UNA ZONA DISCRETA DE UNA FORMULACION B QUE LLEVA UN SEGUNDO VEHICULO COMBINADO CON UN ANTIBITAMINICO DE UN PIPERIDINO - ALCANOL O UNA SAL SUYA, SIENDO EL SEGUNDO VEHICULO UNA MEZCLA DE 0.5 A 25% EN PESO DE CARBONATO CALCICO CON RESPECTO A LA FORMULACION B, DE 1 A 10% EN PESO DE UNO O MAS TENSIOACTIVOS NO IONICOS Y UNO O MAS DE OTROS EXCIPIENTES, CON LA CONDICION DE QUE EL COMPRIMIDO TENGA EN EL NUCLEO LA FORMULACION A Y EN LA ZONA EXTERIOR LA FORMULACION B.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10593987A | 1987-10-07 | 1987-10-07 | |
| US21130888A | 1988-06-24 | 1988-06-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2046270T3 true ES2046270T3 (es) | 1994-02-01 |
Family
ID=26803117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198888116540T Expired - Lifetime ES2046270T3 (es) | 1987-10-07 | 1988-10-06 | Un procedimiento para fabricar una composicion farmaceutica en forma de una tableta de compresion multiple. |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0311067B1 (es) |
| JP (1) | JP2722219B2 (es) |
| KR (1) | KR960007748B1 (es) |
| CN (1) | CN1053570C (es) |
| AU (1) | AU608069B2 (es) |
| CA (1) | CA1314485C (es) |
| DE (1) | DE3874072T2 (es) |
| DK (1) | DK168270B1 (es) |
| ES (1) | ES2046270T3 (es) |
| FI (1) | FI89241C (es) |
| GR (1) | GR3005542T3 (es) |
| HU (1) | HU200916B (es) |
| IE (1) | IE61130B1 (es) |
| IL (1) | IL87943A (es) |
| NO (1) | NO176746C (es) |
| NZ (1) | NZ226482A (es) |
| PH (1) | PH26155A (es) |
| PT (1) | PT88682B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5314697A (en) * | 1992-10-23 | 1994-05-24 | Schering Corporation | Stable extended release oral dosage composition comprising loratadine and pseudoephedrine |
| CZ284822B6 (cs) * | 1993-06-14 | 1999-03-17 | Janssen Pharmaceutica N. V. | Tableta a způsob její výroby |
| WO1996026726A1 (en) * | 1995-02-28 | 1996-09-06 | Hoechst Marion Roussel, Inc. | Pharmaceutical composition for piperidinoalkanol compounds |
| CA2217233A1 (en) * | 1995-04-03 | 1996-10-10 | Chugai Seiyaku Kabushiki Kaisha | Sucralfate containing pharmaceutical composition |
| EP0811374A1 (en) | 1996-05-29 | 1997-12-10 | Pfizer Inc. | Combination dosage form comprising cetirizine and pseudoephedrine |
| UA60335C2 (uk) * | 1997-08-26 | 2003-10-15 | Хехст Маріон Рассел, Інк. | Фармацевтична композиція, яка об'єднує піперидиноалканол з протинабряковим агентом |
| US6194431B1 (en) | 1998-04-14 | 2001-02-27 | Paul D. Rubin | Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors |
| US6232351B1 (en) * | 1998-05-22 | 2001-05-15 | Amway Corporation | Co-processed botanical plant composition |
| US6267986B1 (en) * | 1999-09-24 | 2001-07-31 | Ranbaxy Laboratories Limited | Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine |
| US20020094345A1 (en) | 2000-10-06 | 2002-07-18 | Sara Abelaira | Pharmaceutical compositions containing epinastine and pseudoephedrine |
| EP2121031B1 (en) * | 2007-03-12 | 2013-10-16 | Nektar Therapeutics | Oligomer-antihistamine conjugates |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3558768A (en) * | 1969-12-19 | 1971-01-26 | Sterling Drug Inc | Sustained release pharmaceutical compositions |
| US3878217A (en) | 1972-01-28 | 1975-04-15 | Richardson Merrell Inc | Alpha-aryl-4-substituted piperidinoalkanol derivatives |
| US4285957A (en) | 1979-04-10 | 1981-08-25 | Richardson-Merrell Inc. | 1-Piperidine-alkanol derivatives, pharmaceutical compositions thereof, and method of use thereof |
| US4254129A (en) | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
| JPS5788117A (en) * | 1980-11-21 | 1982-06-01 | Smithkline Corp | Gelatin capsule containing triamterene |
| JPS5877810A (ja) * | 1981-11-01 | 1983-05-11 | Taiho Yakuhin Kogyo Kk | ポリグリセロ−ル不飽和脂肪酸エステルを含む経口薬剤組成物 |
| IT1198386B (it) * | 1982-07-06 | 1988-12-21 | Lepetit Spa | Un prodotto a rilascio protratto contenente il suloctidile |
| ZA838033B (en) * | 1982-11-01 | 1984-06-27 | Merrell Dow Pharma | Sustained release solid dosage forms having non-uniform distribution of active ingredient |
| IL70071A (en) * | 1982-11-01 | 1987-12-31 | Merrell Dow Pharma | Multilayered sustained release pharmaceutical tablets having non-uniform distribution of active ingredient |
| GB2142824B (en) * | 1983-07-07 | 1987-02-11 | American Home Prod | Pharmaceutical composition containing a liquid lubricant |
-
1988
- 1988-09-30 CN CN88106981A patent/CN1053570C/zh not_active Expired - Lifetime
- 1988-10-03 FI FI884545A patent/FI89241C/fi not_active IP Right Cessation
- 1988-10-04 CA CA000579286A patent/CA1314485C/en not_active Expired - Lifetime
- 1988-10-05 AU AU23459/88A patent/AU608069B2/en not_active Expired
- 1988-10-05 PH PH37643A patent/PH26155A/en unknown
- 1988-10-05 JP JP63250047A patent/JP2722219B2/ja not_active Expired - Lifetime
- 1988-10-06 NZ NZ226482A patent/NZ226482A/xx unknown
- 1988-10-06 DK DK559088A patent/DK168270B1/da active IP Right Grant
- 1988-10-06 IL IL87943A patent/IL87943A/xx active Protection Beyond IP Right Term
- 1988-10-06 ES ES198888116540T patent/ES2046270T3/es not_active Expired - Lifetime
- 1988-10-06 EP EP88116540A patent/EP0311067B1/en not_active Expired - Lifetime
- 1988-10-06 NO NO884443A patent/NO176746C/no not_active IP Right Cessation
- 1988-10-06 PT PT88682A patent/PT88682B/pt not_active IP Right Cessation
- 1988-10-06 DE DE8888116540T patent/DE3874072T2/de not_active Expired - Lifetime
- 1988-10-06 HU HU885184A patent/HU200916B/hu unknown
- 1988-10-06 IE IE303388A patent/IE61130B1/en not_active IP Right Cessation
- 1988-10-07 KR KR1019880013062A patent/KR960007748B1/ko not_active IP Right Cessation
-
1992
- 1992-08-27 GR GR920401871T patent/GR3005542T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ226482A (en) | 1990-09-26 |
| IE883033L (en) | 1989-04-07 |
| DK559088D0 (da) | 1988-10-06 |
| DK559088A (da) | 1989-04-08 |
| AU608069B2 (en) | 1991-03-21 |
| IL87943A0 (en) | 1989-03-31 |
| CA1314485C (en) | 1993-03-16 |
| JPH01128925A (ja) | 1989-05-22 |
| KR890006236A (ko) | 1989-06-12 |
| PT88682A (pt) | 1988-11-01 |
| HU200916B (en) | 1990-09-28 |
| DK168270B1 (da) | 1994-03-07 |
| AU2345988A (en) | 1989-04-20 |
| PT88682B (pt) | 1992-12-31 |
| EP0311067A1 (en) | 1989-04-12 |
| JP2722219B2 (ja) | 1998-03-04 |
| FI89241B (fi) | 1993-05-31 |
| FI89241C (fi) | 1993-09-10 |
| NO884443L (no) | 1989-04-10 |
| IE61130B1 (en) | 1994-10-05 |
| NO176746B (no) | 1995-02-13 |
| FI884545A0 (fi) | 1988-10-03 |
| CN1032738A (zh) | 1989-05-10 |
| NO176746C (no) | 1995-05-24 |
| DE3874072D1 (de) | 1992-10-01 |
| EP0311067B1 (en) | 1992-08-26 |
| HUT48816A (en) | 1989-07-28 |
| FI884545A (fi) | 1989-04-08 |
| GR3005542T3 (es) | 1993-06-07 |
| IL87943A (en) | 1992-02-16 |
| CN1053570C (zh) | 2000-06-21 |
| NO884443D0 (no) | 1988-10-06 |
| KR960007748B1 (ko) | 1996-06-12 |
| PH26155A (en) | 1992-03-18 |
| DE3874072T2 (de) | 1993-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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