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ES2006622A6 - Procedimiento de preparacion de nuevas aminas triciclicas derivadas del 5,6,7,8-tetrahidro-(2,3b)-nafto-2,3-dihidrofurano, y de 6,7,8,9-tetrahidro-(2,3b)-5h-benzociclohepta-2,3-dihidro-furano. - Google Patents

Procedimiento de preparacion de nuevas aminas triciclicas derivadas del 5,6,7,8-tetrahidro-(2,3b)-nafto-2,3-dihidrofurano, y de 6,7,8,9-tetrahidro-(2,3b)-5h-benzociclohepta-2,3-dihidro-furano.

Info

Publication number
ES2006622A6
ES2006622A6 ES8801010A ES8801010A ES2006622A6 ES 2006622 A6 ES2006622 A6 ES 2006622A6 ES 8801010 A ES8801010 A ES 8801010A ES 8801010 A ES8801010 A ES 8801010A ES 2006622 A6 ES2006622 A6 ES 2006622A6
Authority
ES
Spain
Prior art keywords
radical
carbon atoms
tetrahydro
benzocyclohepta
dihydrofuran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8801010A
Other languages
English (en)
Inventor
Jean Louis Peglion
Jean-Claude Poignant
Joel Vian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Publication of ES2006622A6 publication Critical patent/ES2006622A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE NUEVAS AMINAS TRICICLICAS DERIVADAS DEL 5,6,7-TETRAHIDRO-(2,3B)-NAFTO-2,3-DIHIDROFURANO Y DE 6,7,8,9-TETRAHIDRO-(2,3B)-5H-BENZOCICLOHEPTA-2,3-DIHIDRO-FURANO. PROCEDIMIENTO DE PREPARACION DE CS DE FORMULA GENERAL I EN LA QUE R1 Y R2 REPRESENTAN RESTOS AROMATICOS, CICLOALQUILICOS O ALQUILICOS EVENTUALMENTE HIDROXILADOS, CARBONILADOS Y ALCOXICARBONILADOS EVENTUALMENTE SUSTITUIDOS; R3 REPRESENTA UN RADICAL ALQUILO INFERIOR Y A REPRESENTA UN ENLACE O UN RADICAL METILENO EVENTUALMENTE ALQUILADO, CARACTERIZADO PORQUE SE CONDENSA BENZOFURANO CON UN DERIVADO ACETILADO DEL ANHIDRIDO ASPARTICO O GLUTAMICO, PARA OBTENER UN COMPUESTO QUE POR ACCION SUCESIVA DE TRIETILSILANO, PENTOXIDO DE FOSFORO E HIDROGENO SOBRE CARBON-PALADIO, CONDUCE A UNA AMIDA DEL MISMO ESQUELETO QUE I, QUE PUEDE SOMETERSE A DIVERSOS PROCEDIMIENTOS DE ALQUILACION DESCRITOS EN EL ARTE, EN FUNCION DE LA NATURALEZA DE LOS SUSTITUYENTES R1 Y
ES8801010A 1987-04-01 1988-03-30 Procedimiento de preparacion de nuevas aminas triciclicas derivadas del 5,6,7,8-tetrahidro-(2,3b)-nafto-2,3-dihidrofurano, y de 6,7,8,9-tetrahidro-(2,3b)-5h-benzociclohepta-2,3-dihidro-furano. Expired ES2006622A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8704550A FR2613364B1 (fr) 1987-04-01 1987-04-01 Nouvelles amines tricycliques derivees du tetrahydro-5, 6, 7, 8 naphto (2, 3b) dihydro-2, 3 furanne, et du tetrahydro-6, 7, 8, 9 5h-benzocyclohepta (2, 3b) dihydro-2, 3 furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ES2006622A6 true ES2006622A6 (es) 1989-05-01

Family

ID=9349664

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8801010A Expired ES2006622A6 (es) 1987-04-01 1988-03-30 Procedimiento de preparacion de nuevas aminas triciclicas derivadas del 5,6,7,8-tetrahidro-(2,3b)-nafto-2,3-dihidrofurano, y de 6,7,8,9-tetrahidro-(2,3b)-5h-benzociclohepta-2,3-dihidro-furano.

Country Status (16)

Country Link
US (2) US4851429A (es)
EP (1) EP0286515B1 (es)
JP (1) JPH068285B2 (es)
AT (1) ATE75470T1 (es)
AU (1) AU602564B2 (es)
CA (1) CA1315283C (es)
DE (1) DE3870510D1 (es)
DK (1) DK165691C (es)
ES (1) ES2006622A6 (es)
FR (1) FR2613364B1 (es)
GR (1) GR1000156B (es)
IE (1) IE61006B1 (es)
NZ (1) NZ224100A (es)
OA (1) OA08725A (es)
PT (1) PT87148B (es)
ZA (1) ZA882281B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2613365B1 (fr) * 1987-04-01 1989-07-28 Adir Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
DK0690843T3 (da) * 1993-03-25 2000-11-13 Upjohn Co Fornyl- eller cyanosubstituerede indolderivater med dopaninerg aktivitet
US5656661A (en) * 1994-07-27 1997-08-12 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
ES2301161T3 (es) * 1994-07-27 2008-06-16 Vanderbilt University Compuestos de dihidrobenzofurano y compuestos relacionados utiles como agentes anti-inflamatorios.
US6071946A (en) * 1994-10-21 2000-06-06 Adir Et Compagnie Tricyclic urea compounds
FR2725985B1 (fr) * 1994-10-21 1996-11-15 Adir Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5998461A (en) * 1994-10-21 1999-12-07 Adir Et Compagnie Tricyclic amide compounds
FR2739379B1 (fr) * 1995-09-29 1997-10-24 Adir Nouveaux composes amines de 5,6,7,8-tetrahydronaphto(2,3-b) furane et d'indano(5,6-b)furane, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US5672620A (en) * 1996-02-01 1997-09-30 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684031A (en) * 1996-02-01 1997-11-04 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US6569968B1 (en) * 1999-08-19 2003-05-27 Kurita Water Industries Ltd. Polymer of a water-soluble radical-polymerizable monomer, process for producing the polymer and flocculant comprising the polymer
DE102020205568B4 (de) 2020-04-30 2022-10-06 Tesa Se Blockcopolymer-basierende Haftklebmasse und Verfahren zu ihrer Herstellung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1084440A (en) * 1963-12-31 1967-09-20 Upjohn Co Improvements in or relating to (2-aminocycloalkyl) hydroquinones and the manufacturethereof
FR2344284A1 (fr) * 1976-03-17 1977-10-14 Cerm Cent Europ Rech Mauvernay Nouveaux composes tricycliques a cycle furannique et leur application comme antidepresseurs
US4470990A (en) * 1983-03-14 1984-09-11 Ayerst, Mckenna & Harrison Inc. 6,7,8,9-Tetrahydronaphtho(1,2-B)furan-8-amine derivatives and their use as dopamine receptor stimulants
US4780480A (en) * 1983-07-14 1988-10-25 Syntex (U.S.A.) Inc. Aroyl benzofuran and benzothiophene acetic and propionic acids
FR2613365B1 (fr) * 1987-04-01 1989-07-28 Adir Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
IE61006B1 (en) 1994-09-07
NZ224100A (en) 1990-03-27
FR2613364A1 (fr) 1988-10-07
AU1404888A (en) 1988-10-06
EP0286515A1 (fr) 1988-10-12
DK178388D0 (da) 1988-03-30
US4851429A (en) 1989-07-25
AU602564B2 (en) 1990-10-18
JPS63258869A (ja) 1988-10-26
DE3870510D1 (de) 1992-06-04
PT87148B (pt) 1992-07-31
DK165691C (da) 1993-06-07
OA08725A (fr) 1989-03-31
GR1000156B (el) 1991-09-27
GR880100207A (en) 1989-01-31
ATE75470T1 (de) 1992-05-15
EP0286515B1 (fr) 1992-04-29
CA1315283C (fr) 1993-03-30
DK178388A (da) 1988-10-02
JPH068285B2 (ja) 1994-02-02
FR2613364B1 (fr) 1989-06-09
US4874878A (en) 1989-10-17
DK165691B (da) 1993-01-04
ZA882281B (en) 1988-09-22
PT87148A (pt) 1988-04-01
IE880970L (en) 1988-10-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000301