DE3870510D1 - Tricyclische 5,6,7,8-tetrahydro-naphtho (2,3b)-2,3-dihydrofuran- und 6,7,8,9-tetrahydro-5h-benzocyclohepta (2,3b)-2,3-dihydrofuranaminderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. - Google Patents
Tricyclische 5,6,7,8-tetrahydro-naphtho (2,3b)-2,3-dihydrofuran- und 6,7,8,9-tetrahydro-5h-benzocyclohepta (2,3b)-2,3-dihydrofuranaminderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.Info
- Publication number
- DE3870510D1 DE3870510D1 DE8888400779T DE3870510T DE3870510D1 DE 3870510 D1 DE3870510 D1 DE 3870510D1 DE 8888400779 T DE8888400779 T DE 8888400779T DE 3870510 T DE3870510 T DE 3870510T DE 3870510 D1 DE3870510 D1 DE 3870510D1
- Authority
- DE
- Germany
- Prior art keywords
- radical
- carbon atoms
- tetrahydro
- production
- tricyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229940126601 medicinal product Drugs 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 7
- -1 cyclohexylmethyl radical Chemical class 0.000 abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 150000003254 radicals Chemical class 0.000 abstract 2
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
- 230000002539 anti-aggressive effect Effects 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 230000001090 anti-dopaminergic effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical compound O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- HZVOZRGWRWCICA-UHFFFAOYSA-N methanediyl Chemical compound [CH2] HZVOZRGWRWCICA-UHFFFAOYSA-N 0.000 abstract 1
- 238000006798 ring closing metathesis reaction Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8704550A FR2613364B1 (fr) | 1987-04-01 | 1987-04-01 | Nouvelles amines tricycliques derivees du tetrahydro-5, 6, 7, 8 naphto (2, 3b) dihydro-2, 3 furanne, et du tetrahydro-6, 7, 8, 9 5h-benzocyclohepta (2, 3b) dihydro-2, 3 furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3870510D1 true DE3870510D1 (de) | 1992-06-04 |
Family
ID=9349664
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8888400779T Expired - Lifetime DE3870510D1 (de) | 1987-04-01 | 1988-03-31 | Tricyclische 5,6,7,8-tetrahydro-naphtho (2,3b)-2,3-dihydrofuran- und 6,7,8,9-tetrahydro-5h-benzocyclohepta (2,3b)-2,3-dihydrofuranaminderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. |
Country Status (16)
Country | Link |
---|---|
US (2) | US4851429A (de) |
EP (1) | EP0286515B1 (de) |
JP (1) | JPH068285B2 (de) |
AT (1) | ATE75470T1 (de) |
AU (1) | AU602564B2 (de) |
CA (1) | CA1315283C (de) |
DE (1) | DE3870510D1 (de) |
DK (1) | DK165691C (de) |
ES (1) | ES2006622A6 (de) |
FR (1) | FR2613364B1 (de) |
GR (1) | GR1000156B (de) |
IE (1) | IE61006B1 (de) |
NZ (1) | NZ224100A (de) |
OA (1) | OA08725A (de) |
PT (1) | PT87148B (de) |
ZA (1) | ZA882281B (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2613365B1 (fr) * | 1987-04-01 | 1989-07-28 | Adir | Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
DK0690843T3 (da) * | 1993-03-25 | 2000-11-13 | Upjohn Co | Fornyl- eller cyanosubstituerede indolderivater med dopaninerg aktivitet |
US5656661A (en) * | 1994-07-27 | 1997-08-12 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
ES2301161T3 (es) * | 1994-07-27 | 2008-06-16 | Vanderbilt University | Compuestos de dihidrobenzofurano y compuestos relacionados utiles como agentes anti-inflamatorios. |
US6071946A (en) * | 1994-10-21 | 2000-06-06 | Adir Et Compagnie | Tricyclic urea compounds |
FR2725985B1 (fr) * | 1994-10-21 | 1996-11-15 | Adir | Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US5998461A (en) * | 1994-10-21 | 1999-12-07 | Adir Et Compagnie | Tricyclic amide compounds |
FR2739379B1 (fr) * | 1995-09-29 | 1997-10-24 | Adir | Nouveaux composes amines de 5,6,7,8-tetrahydronaphto(2,3-b) furane et d'indano(5,6-b)furane, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
US5672620A (en) * | 1996-02-01 | 1997-09-30 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
US5684031A (en) * | 1996-02-01 | 1997-11-04 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
US6569968B1 (en) * | 1999-08-19 | 2003-05-27 | Kurita Water Industries Ltd. | Polymer of a water-soluble radical-polymerizable monomer, process for producing the polymer and flocculant comprising the polymer |
DE102020205568B4 (de) | 2020-04-30 | 2022-10-06 | Tesa Se | Blockcopolymer-basierende Haftklebmasse und Verfahren zu ihrer Herstellung |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1084440A (en) * | 1963-12-31 | 1967-09-20 | Upjohn Co | Improvements in or relating to (2-aminocycloalkyl) hydroquinones and the manufacturethereof |
FR2344284A1 (fr) * | 1976-03-17 | 1977-10-14 | Cerm Cent Europ Rech Mauvernay | Nouveaux composes tricycliques a cycle furannique et leur application comme antidepresseurs |
US4470990A (en) * | 1983-03-14 | 1984-09-11 | Ayerst, Mckenna & Harrison Inc. | 6,7,8,9-Tetrahydronaphtho(1,2-B)furan-8-amine derivatives and their use as dopamine receptor stimulants |
US4780480A (en) * | 1983-07-14 | 1988-10-25 | Syntex (U.S.A.) Inc. | Aroyl benzofuran and benzothiophene acetic and propionic acids |
FR2613365B1 (fr) * | 1987-04-01 | 1989-07-28 | Adir | Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
-
1987
- 1987-04-01 FR FR8704550A patent/FR2613364B1/fr not_active Expired
-
1988
- 1988-03-22 CA CA000562141A patent/CA1315283C/fr not_active Expired - Fee Related
- 1988-03-25 US US07/173,286 patent/US4851429A/en not_active Expired - Fee Related
- 1988-03-30 ZA ZA882281A patent/ZA882281B/xx unknown
- 1988-03-30 ES ES8801010A patent/ES2006622A6/es not_active Expired
- 1988-03-30 DK DK178388A patent/DK165691C/da active
- 1988-03-31 NZ NZ224100A patent/NZ224100A/xx unknown
- 1988-03-31 IE IE97088A patent/IE61006B1/en not_active IP Right Cessation
- 1988-03-31 EP EP88400779A patent/EP0286515B1/de not_active Expired - Lifetime
- 1988-03-31 JP JP63080187A patent/JPH068285B2/ja not_active Expired - Lifetime
- 1988-03-31 GR GR880100207A patent/GR1000156B/el unknown
- 1988-03-31 PT PT87148A patent/PT87148B/pt not_active IP Right Cessation
- 1988-03-31 AU AU14048/88A patent/AU602564B2/en not_active Ceased
- 1988-03-31 AT AT88400779T patent/ATE75470T1/de not_active IP Right Cessation
- 1988-03-31 DE DE8888400779T patent/DE3870510D1/de not_active Expired - Lifetime
- 1988-03-31 OA OA59314A patent/OA08725A/xx unknown
-
1989
- 1989-01-24 US US07/301,160 patent/US4874878A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
IE61006B1 (en) | 1994-09-07 |
NZ224100A (en) | 1990-03-27 |
FR2613364A1 (fr) | 1988-10-07 |
AU1404888A (en) | 1988-10-06 |
ES2006622A6 (es) | 1989-05-01 |
EP0286515A1 (de) | 1988-10-12 |
DK178388D0 (da) | 1988-03-30 |
US4851429A (en) | 1989-07-25 |
AU602564B2 (en) | 1990-10-18 |
JPS63258869A (ja) | 1988-10-26 |
PT87148B (pt) | 1992-07-31 |
DK165691C (da) | 1993-06-07 |
OA08725A (fr) | 1989-03-31 |
GR1000156B (el) | 1991-09-27 |
GR880100207A (en) | 1989-01-31 |
ATE75470T1 (de) | 1992-05-15 |
EP0286515B1 (de) | 1992-04-29 |
CA1315283C (fr) | 1993-03-30 |
DK178388A (da) | 1988-10-02 |
JPH068285B2 (ja) | 1994-02-02 |
FR2613364B1 (fr) | 1989-06-09 |
US4874878A (en) | 1989-10-17 |
DK165691B (da) | 1993-01-04 |
ZA882281B (en) | 1988-09-22 |
PT87148A (pt) | 1988-04-01 |
IE880970L (en) | 1988-10-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |