EP3994142A4 - Chemische verbindungen - Google Patents

Chemische verbindungen Download PDF

Info

Publication number: EP3994142A4
Authority: EP; European Patent Office
Prior art keywords: chemical compounds; compounds; chemical
Prior art date: 2019-07-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

EP20835242.7A

Other languages

English (en)

French (fr)

Other versions

EP3994142A1 (de

Inventor

Yasheen Zhou

Chun Yu LIU

Chunliang Liu

Yong-Kang Zhang

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Borah Inc

Original Assignee

Borah Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2019-07-03

Filing date

2020-07-02

Publication date

2023-09-06

2020-07-02 Application filed by Borah Inc filed Critical Borah Inc

2022-05-11 Publication of EP3994142A1 publication Critical patent/EP3994142A1/de

2023-09-06 Publication of EP3994142A4 publication Critical patent/EP3994142A4/de

Status Pending legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP20835242.7A 2019-07-03 2020-07-02 Chemische verbindungen Pending EP3994142A4 (de)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US201962870537P	2019-07-03	2019-07-03
US201962916697P	2019-10-17	2019-10-17
US201962916700P	2019-10-17	2019-10-17
US201962949280P	2019-12-17	2019-12-17
US201962949301P	2019-12-17	2019-12-17
PCT/US2020/070234 WO2021003501A1 (en)	2019-07-03	2020-07-02	Chemical compounds

Publications (2)

Publication Number	Publication Date
EP3994142A1 EP3994142A1 (de)	2022-05-11
EP3994142A4 true EP3994142A4 (de)	2023-09-06

Family

ID=74101303

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP20835242.7A Pending EP3994142A4 (de)	2019-07-03	2020-07-02	Chemische verbindungen

Country Status (10)

Country	Link
US (1)	US20240368196A1 (de)
EP (1)	EP3994142A4 (de)
JP (1)	JP7597781B2 (de)
KR (1)	KR20220031662A (de)
CN (1)	CN114341145B (de)
AU (1)	AU2020300689A1 (de)
BR (1)	BR112021026754A2 (de)
CA (1)	CA3145813A1 (de)
MX (1)	MX2022000140A (de)
WO (1)	WO2021003501A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2023295285A1 (en) *	2022-06-17	2024-12-05	Borah, Inc.	Boron containing pyrimidine compounds, compositions comprising them, methods and uses thereof
CN115772115B (zh) *	2023-02-10	2023-05-05	夏禾科技(江苏)有限公司	一种芳基吡啶溴代衍生物的合成方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN108329274A (zh) *	2017-01-13	2018-07-27	正大天晴药业集团股份有限公司	布鲁顿酪氨酸激酶抑制剂

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2009106442A1 (en) *	2008-02-25	2009-09-03	F. Hoffmann-La Roche Ag	Pyrrolopyrazine kinase inhibitors
EP3246034A1 (de) *	2008-03-06	2017-11-22	Anacor Pharmaceuticals, Inc.	Boronhaltige kleinmoleküle als entzündungshemmende wirkstoffe
WO2010028005A1 (en) *	2008-09-04	2010-03-11	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules
WO2010027975A1 (en)	2008-09-04	2010-03-11	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules
GB2465405A (en) *	2008-11-10	2010-05-19	Univ Basel	Triazine, pyrimidine and pyridine analogues and their use in therapy
US8343944B2 (en) *	2009-07-28	2013-01-01	Anacor Pharmaceuticals, Inc.	Trisubstituted boron-containing molecules
DK2912019T3 (da) *	2012-10-25	2021-05-25	Tetra Discovery Partners Llc	Heteroarylhæmmere af pde4
CN108341835B (zh) *	2017-01-22	2021-01-15	正大天晴药业集团股份有限公司	用作酪氨酸激酶抑制剂的含硼化合物
WO2019079357A1 (en) *	2017-10-17	2019-04-25	Silverback Therapeutics, Inc.	TNIK MODULATORS, CONJUGATES AND USES THEREOF

2020
- 2020-07-02 KR KR1020227003771A patent/KR20220031662A/ko not_active Withdrawn
- 2020-07-02 EP EP20835242.7A patent/EP3994142A4/de active Pending
- 2020-07-02 CN CN202080061712.8A patent/CN114341145B/zh active Active
- 2020-07-02 US US17/623,961 patent/US20240368196A1/en active Pending
- 2020-07-02 BR BR112021026754A patent/BR112021026754A2/pt unknown
- 2020-07-02 MX MX2022000140A patent/MX2022000140A/es unknown
- 2020-07-02 CA CA3145813A patent/CA3145813A1/en active Pending
- 2020-07-02 JP JP2022500522A patent/JP7597781B2/ja active Active
- 2020-07-02 AU AU2020300689A patent/AU2020300689A1/en active Pending
- 2020-07-02 WO PCT/US2020/070234 patent/WO2021003501A1/en unknown

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN108329274A (zh) *	2017-01-13	2018-07-27	正大天晴药业集团股份有限公司	布鲁顿酪氨酸激酶抑制剂

Also Published As

Publication number	Publication date
KR20220031662A (ko)	2022-03-11
US20240368196A1 (en)	2024-11-07
CN114341145A (zh)	2022-04-12
BR112021026754A2 (pt)	2022-03-03
EP3994142A1 (de)	2022-05-11
JP2022538495A (ja)	2022-09-02
CN114341145B (zh)	2024-08-16
CA3145813A1 (en)	2021-01-07
WO2021003501A1 (en)	2021-01-07
AU2020300689A1 (en)	2022-02-24
MX2022000140A (es)	2022-04-27
JP7597781B2 (ja)	2024-12-10

Publication	Publication Date	Title
EP3836923A4 (de)	2022-05-18	Pyrrolo-dipyridinverbindungen
EP3877356A4 (de)	2022-06-22	Bicyclische verbindungen
EP3868764A4 (de)	2022-06-29	Sting-agonisten-verbindung
EP4061364A4 (de)	2023-09-13	Heteroarylverbindungen
EP3924358A4 (de)	2023-07-05	Makrocyclische verbindungen
EP3790385A4 (de)	2022-03-30	Stabilisierte chemische zusammensetzung
EP4077318A4 (de)	2023-11-22	Verbindungen
EP3998262A4 (de)	2023-07-26	Nrf2-aktivierende verbindung
EP3908285A4 (de)	2022-10-19	Organische verbindungen
EP3897656A4 (de)	2022-09-21	Organische verbindungen
EP3994142A4 (de)	2023-09-06	Chemische verbindungen
EP3969458A4 (de)	2023-05-17	Chemische verbindungen
EP3917932A4 (de)	2022-09-28	Chemische verbindungen
EP3733682A4 (de)	2021-03-24	Neuartige, aus allulose gewonnene verbindung
EP3920906A4 (de)	2023-07-12	Bisphosphonatgebundene verbindungen
EP4025202A4 (de)	2023-08-02	Neuartige verbindungen
GB201907352D0 (en)	2019-07-10	Chemical compounds
GB201903745D0 (en)	2019-05-01	Chemical compounds
AU2019903146A0 (en)	2019-09-12	Novel compounds
AU2019902391A0 (en)	2019-07-18	Novel Compounds
AU2021904269A0 (en)	2022-01-13	Compounds
AU2021904274A0 (en)	2022-01-13	Compounds
AU2021904268A0 (en)	2022-01-13	Compounds
AU2021903120A0 (en)	2021-10-14	Compounds
AU2021901886A0 (en)	2021-07-08	Compounds

Legal Events

Date	Code	Title	Description
2021-01-15	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE
2022-04-08	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2022-04-08	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE
2022-05-11	17P	Request for examination filed	Effective date: 20220127
2022-05-11	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2022-10-12	DAV	Request for validation of the european patent (deleted)
2022-10-12	DAX	Request for extension of the european patent (deleted)
2022-12-09	REG	Reference to a national code	Ref country code: HK Ref legal event code: DE Ref document number: 40073237 Country of ref document: HK
2023-09-06	A4	Supplementary search report drawn up and despatched	Effective date: 20230808
2023-09-06	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 45/06 20060101ALI20230802BHEP Ipc: A61P 19/02 20060101ALI20230802BHEP Ipc: A61P 17/06 20060101ALI20230802BHEP Ipc: A61P 35/00 20060101ALI20230802BHEP Ipc: A61P 37/00 20060101ALI20230802BHEP Ipc: A61P 29/00 20060101ALI20230802BHEP Ipc: A61K 31/69 20060101ALI20230802BHEP Ipc: C07F 5/02 20060101AFI20230802BHEP