EP3143379A4 - Microfluidic flow cell assemblies for imaging and method of use - Google Patents
Microfluidic flow cell assemblies for imaging and method of use Download PDFInfo
- Publication number
- EP3143379A4 EP3143379A4 EP15792752.6A EP15792752A EP3143379A4 EP 3143379 A4 EP3143379 A4 EP 3143379A4 EP 15792752 A EP15792752 A EP 15792752A EP 3143379 A4 EP3143379 A4 EP 3143379A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- imaging
- flow cell
- cell assemblies
- microfluidic flow
- microfluidic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/30—Mixers with shaking, oscillating, or vibrating mechanisms comprising a receptacle to only a part of which the shaking, oscillating, or vibrating movement is imparted
- B01F31/31—Mixers with shaking, oscillating, or vibrating mechanisms comprising a receptacle to only a part of which the shaking, oscillating, or vibrating movement is imparted using receptacles with deformable parts, e.g. membranes, to which a motion is imparted
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/025—Align devices or objects to ensure defined positions relative to each other
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/028—Modular arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0874—Three dimensional network
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/277,503 US9080941B2 (en) | 2012-04-27 | 2014-05-14 | Microfluidic flow cell assemblies for imaging and method of use |
PCT/US2015/027549 WO2015175188A1 (en) | 2014-05-14 | 2015-04-24 | Microfluidic flow cell assemblies for imaging and method of use |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3143379A1 EP3143379A1 (en) | 2017-03-22 |
EP3143379A4 true EP3143379A4 (en) | 2017-05-31 |
Family
ID=54480428
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15792752.6A Ceased EP3143379A4 (en) | 2014-05-14 | 2015-04-24 | Microfluidic flow cell assemblies for imaging and method of use |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP3143379A4 (en) |
JP (1) | JP6723541B2 (en) |
WO (1) | WO2015175188A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150166956A1 (en) * | 2013-12-16 | 2015-06-18 | General Electric Company | Devices for separation of particulates, associated methods and systems |
FR3063990A1 (en) * | 2017-03-17 | 2018-09-21 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | MICRO-FLUIDIC DEVICE |
ES2992887T3 (en) | 2017-04-27 | 2024-12-19 | Mochida Pharm Co Ltd | Novel tetrahydronaphthyl urea derivatives as inhibitors of tropomyosin receptor kinase a for the treatment of pain |
US11326989B2 (en) * | 2017-10-26 | 2022-05-10 | Essenlix Corporation | Devices and methods for tissue and cell staining |
CA3134919C (en) | 2019-03-26 | 2022-11-15 | Siemens Healthcare Diagnostics Inc. | Methods and apparatus for performing sample measurements using visible light on samples manipulated with acoustic waves |
CA3155289A1 (en) * | 2019-09-23 | 2021-04-01 | Element Biosciences, Inc. | Methods for cellularly addressable nucleic acid sequencing |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020185184A1 (en) * | 2001-06-07 | 2002-12-12 | Nanostream, Inc. | Microfluidic synthesis devices and methods |
WO2003015922A1 (en) * | 2001-08-20 | 2003-02-27 | Biomicro Systems, Inc. | Laminated microarray interface device |
US20050019898A1 (en) * | 2001-03-09 | 2005-01-27 | Nils Adey | Fluid mixing in low aspect ratio chambers |
US20090081464A1 (en) * | 2005-12-06 | 2009-03-26 | Philip Summersgill | Fine Line Bonding and/or Sealing System and Method |
US20100179068A1 (en) * | 2007-05-03 | 2010-07-15 | Clondiag Gmbh | Assays |
EP2388500A1 (en) * | 2010-05-18 | 2011-11-23 | Samsung Electronics Co., Ltd. | Microvalve device and method of manufacturing the same |
US20120128548A1 (en) * | 2007-08-14 | 2012-05-24 | Arcxis Biotechnologies | Polymer microfluidic biochip fabrication |
WO2013106458A2 (en) * | 2012-01-09 | 2013-07-18 | Micronics, Inc. | Microfluidic reactor system |
US20130287645A1 (en) * | 2012-04-27 | 2013-10-31 | General Electric Company | Microfluidic chamber device and fabrication |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5147606A (en) * | 1990-08-06 | 1992-09-15 | Miles Inc. | Self-metering fluid analysis device |
US5872582A (en) * | 1996-07-02 | 1999-02-16 | Hewlett-Packard Company | Microfluid valve for modulating fluid flow within an ink-jet printer |
JP3777112B2 (en) * | 2001-11-02 | 2006-05-24 | 財団法人川村理化学研究所 | Microfluidic device and manufacturing method thereof |
WO2004103563A2 (en) * | 2003-05-20 | 2004-12-02 | Fluidigm Corporation | Method and system for microfluidic device and imaging thereof |
JP2007322284A (en) * | 2006-06-01 | 2007-12-13 | Konica Minolta Medical & Graphic Inc | Microchip and filling method of reagent in microchip |
US9494500B2 (en) * | 2012-10-29 | 2016-11-15 | Academia Sinica | Collection and concentration system for biologic substance of interest and use thereof |
-
2015
- 2015-04-24 EP EP15792752.6A patent/EP3143379A4/en not_active Ceased
- 2015-04-24 JP JP2016567401A patent/JP6723541B2/en active Active
- 2015-04-24 WO PCT/US2015/027549 patent/WO2015175188A1/en active Application Filing
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050019898A1 (en) * | 2001-03-09 | 2005-01-27 | Nils Adey | Fluid mixing in low aspect ratio chambers |
US20020185184A1 (en) * | 2001-06-07 | 2002-12-12 | Nanostream, Inc. | Microfluidic synthesis devices and methods |
WO2003015922A1 (en) * | 2001-08-20 | 2003-02-27 | Biomicro Systems, Inc. | Laminated microarray interface device |
US20090081464A1 (en) * | 2005-12-06 | 2009-03-26 | Philip Summersgill | Fine Line Bonding and/or Sealing System and Method |
US20100179068A1 (en) * | 2007-05-03 | 2010-07-15 | Clondiag Gmbh | Assays |
US20120128548A1 (en) * | 2007-08-14 | 2012-05-24 | Arcxis Biotechnologies | Polymer microfluidic biochip fabrication |
EP2388500A1 (en) * | 2010-05-18 | 2011-11-23 | Samsung Electronics Co., Ltd. | Microvalve device and method of manufacturing the same |
WO2013106458A2 (en) * | 2012-01-09 | 2013-07-18 | Micronics, Inc. | Microfluidic reactor system |
US20130287645A1 (en) * | 2012-04-27 | 2013-10-31 | General Electric Company | Microfluidic chamber device and fabrication |
Non-Patent Citations (1)
Title |
---|
See also references of WO2015175188A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP3143379A1 (en) | 2017-03-22 |
WO2015175188A1 (en) | 2015-11-19 |
JP6723541B2 (en) | 2020-07-15 |
JP2017516099A (en) | 2017-06-15 |
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Extension state: BA ME |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20170504 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: G01N 21/64 20060101ALI20170426BHEP Ipc: B01F 11/00 20060101ALI20170426BHEP Ipc: B01J 19/00 20060101ALI20170426BHEP Ipc: G01N 21/03 20060101ALI20170426BHEP Ipc: G01N 21/05 20060101AFI20170426BHEP Ipc: F16K 99/00 20060101ALI20170426BHEP Ipc: B01L 3/00 20060101ALI20170426BHEP |
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