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EP3068432A4 - Compositions contenant des cellules de perfusat placentaire humain, des sous-populations de celles-ci, et leurs utilisations - Google Patents

Compositions contenant des cellules de perfusat placentaire humain, des sous-populations de celles-ci, et leurs utilisations Download PDF

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Publication number
EP3068432A4
EP3068432A4 EP14862931.4A EP14862931A EP3068432A4 EP 3068432 A4 EP3068432 A4 EP 3068432A4 EP 14862931 A EP14862931 A EP 14862931A EP 3068432 A4 EP3068432 A4 EP 3068432A4
Authority
EP
European Patent Office
Prior art keywords
subpopulations
compositions
human placental
placental perfusate
perfusate cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP14862931.4A
Other languages
German (de)
English (en)
Other versions
EP3068432A2 (fr
Inventor
Jodi P. Gurney
Xiaokui Zhang
Stacy HERB
Robert J. Hariri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celularity Inc
Original Assignee
Anthrogenesis Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anthrogenesis Corp filed Critical Anthrogenesis Corp
Publication of EP3068432A2 publication Critical patent/EP3068432A2/fr
Publication of EP3068432A4 publication Critical patent/EP3068432A4/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP14862931.4A 2013-11-15 2014-11-14 Compositions contenant des cellules de perfusat placentaire humain, des sous-populations de celles-ci, et leurs utilisations Pending EP3068432A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361905077P 2013-11-15 2013-11-15
US201361905076P 2013-11-15 2013-11-15
PCT/US2014/065665 WO2015073800A2 (fr) 2013-11-15 2014-11-14 Compositions contenant des cellules de perfusat placentaire humain, des sous-populations de celles-ci, et leurs utilisations

Publications (2)

Publication Number Publication Date
EP3068432A2 EP3068432A2 (fr) 2016-09-21
EP3068432A4 true EP3068432A4 (fr) 2017-04-19

Family

ID=53058264

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14862931.4A Pending EP3068432A4 (fr) 2013-11-15 2014-11-14 Compositions contenant des cellules de perfusat placentaire humain, des sous-populations de celles-ci, et leurs utilisations

Country Status (11)

Country Link
US (2) US20160279171A1 (fr)
EP (1) EP3068432A4 (fr)
JP (4) JP2016537362A (fr)
KR (3) KR20210121277A (fr)
CN (2) CN105916521A (fr)
AU (3) AU2014348454A1 (fr)
CA (1) CA2930573C (fr)
MX (2) MX2016006270A (fr)
RU (1) RU2016123361A (fr)
WO (1) WO2015073800A2 (fr)
ZA (1) ZA201603270B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11707491B2 (en) * 2016-11-11 2023-07-25 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Methods of treating neurodegenerative disorders
CA3056406A1 (fr) 2017-03-15 2018-09-20 Orca Biosystems Inc. Compositions et procedes de greffe de cellules souches hematopoietiques
EP3886876A1 (fr) * 2018-11-30 2021-10-06 Celularity Inc. Cellules car-t allogéniques dérivées de placenta et leurs utilisations

Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002064755A2 (fr) * 2001-02-14 2002-08-22 Anthrogenesis Corporation Placenta post-gravidique de mammifere, son utilisation et cellules souches placentaires correspondantes
WO2007079184A2 (fr) * 2005-12-29 2007-07-12 Anthrogenesis Corporation Co-culture de cellules souches placentaires et cellules souches provenant d'une seconde source
WO2007079183A2 (fr) * 2005-12-29 2007-07-12 Anthrogenesis Corporation Populations de cellules souches placentaires
WO2008051568A2 (fr) * 2006-10-23 2008-05-02 Anthrogenesis Corporation Procédés et compositions pour le traitement de déficits osseux au moyen de populations de cellules placentaires
WO2008100497A1 (fr) * 2007-02-12 2008-08-21 Anthrogenesis Corporation Hépatocytes et chondrocytes provenant de cellules souches placentaires adhérentes ; et populations de cellules enrichies avec des cellules souches placentaires cd34+, cd45-
WO2009042201A1 (fr) * 2007-09-26 2009-04-02 Celgene Cellular Therapeutics Cellules angiogéniques provenant d'un perfusat placentaire humain
WO2009045360A2 (fr) * 2007-09-28 2009-04-09 Celgene Cellular Therapeutics Elimination des tumeurs au moyen d'un perfusat placentaire humain et de cellules tueuses naturelles intermediaires provenant d'un placenta humain
WO2010060031A1 (fr) * 2008-11-21 2010-05-27 Anthrogenesis Corporation Traitement de maladies, troubles ou états du poumon utilisant des cellules placentaires
US20110250182A1 (en) * 2010-04-07 2011-10-13 Anthrogenesis Corporation Angiogenesis using placental stem cells
US20110280849A1 (en) * 2010-03-26 2011-11-17 Anthrogenesis Corporation Tumor suppression using human placenta-derived intermediate natural killer cells and immunomodulatory compounds
WO2012083023A1 (fr) * 2010-12-17 2012-06-21 Anthrogenesis Corporation Traitement de lésion médullaire et de lésion cérébrale traumatique au moyen de cellules adhérentes dérivées de l'amnios
WO2012083021A1 (fr) * 2010-12-17 2012-06-21 Anthrogenesis Corporation Traitement de maladies et de troubles liés à la réponse immune au moyen de cellules adhérentes dérivées de l'amnios
US20120171180A1 (en) * 2010-12-30 2012-07-05 Sascha Abramson Compositions comprising amnion derived adherent cells and platelet-rich plasma
WO2013055476A1 (fr) * 2011-09-09 2013-04-18 Anthrogenesis Corporation Traitement de la sclérose latérale amyotrophique au moyen de cellules souches placentaires
WO2014028453A2 (fr) * 2012-08-13 2014-02-20 Anthrogenesis Corporation Cellules tueuses naturelles et leurs utilisations
WO2014063035A2 (fr) * 2012-10-19 2014-04-24 Anthrogenesis Corporation Traitement de la douleur utilisant des cellules adhérentes dérivées de la membrane amniotique

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10001172A1 (de) 2000-01-13 2001-07-26 Max Planck Gesellschaft Templatieren von Feststoffpartikeln mit Polymermultischichten
DK1349918T3 (da) 2000-12-06 2014-11-10 Anthrogenesis Corp Fremgangsmåde til indsamling af stamceller fra moderkagen
US20080152629A1 (en) * 2000-12-06 2008-06-26 James Edinger Placental stem cell populations
US7311905B2 (en) * 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
KR101132545B1 (ko) * 2001-02-14 2012-04-02 안트로제네시스 코포레이션 산후 포유류의 태반, 이의 용도 및 태반 줄기세포
US7498171B2 (en) * 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
WO2005094353A2 (fr) * 2004-03-29 2005-10-13 Cytomatrix, Llc Techniques de production de lymphocytes t regulateurs et utilisation de ceux-ci
CA2856662C (fr) * 2005-10-13 2017-09-05 Anthrogenesis Corporation Immunomodulation realisee avec des cellules souches placentaires
CA2909053C (fr) * 2006-05-11 2021-02-09 Cord Blood Science Inc. Procedes destines a prelever et a utiliser des cellules souches de sang placentaire de cordon ombilical
WO2008156659A1 (fr) * 2007-06-18 2008-12-24 Children's Hospital & Research Center At Oakland Procédé permettant d'isoler du placenta des cellules souches et progénitrices
WO2010105144A2 (fr) * 2009-03-12 2010-09-16 University Of South Florida Procédé de neuroprotection de cellules souches médiée par un récepteur et induite par une maladie
WO2010141654A1 (fr) * 2009-06-05 2010-12-09 Anthrogenesis Corporation Procédé amélioré de collecte de cellules placentaires
EP2454362A4 (fr) * 2009-07-14 2013-02-27 Massachusetts Inst Technology Cellules progénitrices stromales hématopoïétiques et utilisations afférentes
AU2011279201B2 (en) * 2010-07-13 2016-01-21 Celularity Inc. Methods of generating natural killer cells

Patent Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002064755A2 (fr) * 2001-02-14 2002-08-22 Anthrogenesis Corporation Placenta post-gravidique de mammifere, son utilisation et cellules souches placentaires correspondantes
WO2007079184A2 (fr) * 2005-12-29 2007-07-12 Anthrogenesis Corporation Co-culture de cellules souches placentaires et cellules souches provenant d'une seconde source
WO2007079183A2 (fr) * 2005-12-29 2007-07-12 Anthrogenesis Corporation Populations de cellules souches placentaires
WO2008051568A2 (fr) * 2006-10-23 2008-05-02 Anthrogenesis Corporation Procédés et compositions pour le traitement de déficits osseux au moyen de populations de cellules placentaires
WO2008100497A1 (fr) * 2007-02-12 2008-08-21 Anthrogenesis Corporation Hépatocytes et chondrocytes provenant de cellules souches placentaires adhérentes ; et populations de cellules enrichies avec des cellules souches placentaires cd34+, cd45-
WO2009042201A1 (fr) * 2007-09-26 2009-04-02 Celgene Cellular Therapeutics Cellules angiogéniques provenant d'un perfusat placentaire humain
WO2009045360A2 (fr) * 2007-09-28 2009-04-09 Celgene Cellular Therapeutics Elimination des tumeurs au moyen d'un perfusat placentaire humain et de cellules tueuses naturelles intermediaires provenant d'un placenta humain
WO2010060031A1 (fr) * 2008-11-21 2010-05-27 Anthrogenesis Corporation Traitement de maladies, troubles ou états du poumon utilisant des cellules placentaires
US20110280849A1 (en) * 2010-03-26 2011-11-17 Anthrogenesis Corporation Tumor suppression using human placenta-derived intermediate natural killer cells and immunomodulatory compounds
US20110250182A1 (en) * 2010-04-07 2011-10-13 Anthrogenesis Corporation Angiogenesis using placental stem cells
WO2012083023A1 (fr) * 2010-12-17 2012-06-21 Anthrogenesis Corporation Traitement de lésion médullaire et de lésion cérébrale traumatique au moyen de cellules adhérentes dérivées de l'amnios
WO2012083021A1 (fr) * 2010-12-17 2012-06-21 Anthrogenesis Corporation Traitement de maladies et de troubles liés à la réponse immune au moyen de cellules adhérentes dérivées de l'amnios
US20120171180A1 (en) * 2010-12-30 2012-07-05 Sascha Abramson Compositions comprising amnion derived adherent cells and platelet-rich plasma
WO2013055476A1 (fr) * 2011-09-09 2013-04-18 Anthrogenesis Corporation Traitement de la sclérose latérale amyotrophique au moyen de cellules souches placentaires
WO2014028453A2 (fr) * 2012-08-13 2014-02-20 Anthrogenesis Corporation Cellules tueuses naturelles et leurs utilisations
WO2014063035A2 (fr) * 2012-10-19 2014-04-24 Anthrogenesis Corporation Traitement de la douleur utilisant des cellules adhérentes dérivées de la membrane amniotique

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHICHA L ET AL: "Stem cells for brain repair in neonatal hypoxia-ischemia", CHILD'S NERVOUS SYSTEM, SPRINGER, BERLIN, DE, vol. 30, no. 1, 1 November 2013 (2013-11-01), pages 37 - 46, XP035357327, ISSN: 0256-7040, [retrieved on 20131101], DOI: 10.1007/S00381-013-2304-4 *
FEIFEI S WANG ET AL: "The Therapeutic Potential of Human Umbilical Cord Blood Transplantation for Neonatal Hypoxic-Ischemic Brain Injury and Ischemic Stroke", SYNTHETIC COMMUNICATIONS, vol. 47, no. 19, 1 January 2012 (2012-01-01), PHILADELPHIA, PA; US, pages 429 - 434, XP055469451, ISSN: 0039-7911, DOI: 10.1080/00397911.2017.1350277 *
See also references of WO2015073800A2 *
SERIKOV V ET AL: "Human term placenta as a source of hematopoietic cells", EXPERIMENTAL BIOLOGY AND MEDICINE, SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, vol. 234, no. 7, 1 January 2009 (2009-01-01), pages 813 - 823, XP009133343, ISSN: 1535-3702, DOI: 10.3181/0809-BC-262 *

Also Published As

Publication number Publication date
JP2024016037A (ja) 2024-02-06
US20160279171A1 (en) 2016-09-29
JP2020019777A (ja) 2020-02-06
MX2021003799A (es) 2021-06-04
KR20160098244A (ko) 2016-08-18
AU2022215291A1 (en) 2022-09-01
KR20210121277A (ko) 2021-10-07
KR20240023709A (ko) 2024-02-22
WO2015073800A3 (fr) 2015-07-02
MX2016006270A (es) 2016-09-07
WO2015073800A8 (fr) 2015-12-17
CA2930573A1 (fr) 2015-05-21
AU2022215291A9 (en) 2022-11-24
JP2016537362A (ja) 2016-12-01
JP2022020622A (ja) 2022-02-01
EP3068432A2 (fr) 2016-09-21
WO2015073800A2 (fr) 2015-05-21
AU2014348454A1 (en) 2016-06-02
CN113679740A (zh) 2021-11-23
US20190117705A1 (en) 2019-04-25
AU2020202182A1 (en) 2020-04-16
CA2930573C (fr) 2023-12-05
CN105916521A (zh) 2016-08-31
ZA201603270B (en) 2022-09-28
RU2016123361A (ru) 2017-12-20

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