EP2900658A4 - Verfahren und polymorphe von 5-[4-[4-(5-cyano-1h-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxamid und dessen salzen - Google Patents

Verfahren und polymorphe von 5-[4-[4-(5-cyano-1h-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxamid und dessen salzen

Info

Publication number: EP2900658A4
Authority: EP; European Patent Office
Prior art keywords: polymorphs; indol; piperazinyl; cyano; butyl
Prior art date: 2012-09-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP13842370.2A

Other languages

English (en)

French (fr)

Other versions

EP2900658A2 (de

Inventor

Rajan Srinivasan Thirumalai

Sajja Eswaraiah

Sunkara Vishnuvardhan

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

MSN Laboratories Pvt Ltd

Original Assignee

MSN Laboratories Pvt Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-09-27

Filing date

2013-09-26

Publication date

2016-07-13

2013-09-26 Application filed by MSN Laboratories Pvt Ltd filed Critical MSN Laboratories Pvt Ltd

2015-08-05 Publication of EP2900658A2 publication Critical patent/EP2900658A2/de

2016-07-13 Publication of EP2900658A4 publication Critical patent/EP2900658A4/de

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

EP13842370.2A 2012-09-27 2013-09-26 Verfahren und polymorphe von 5-[4-[4-(5-cyano-1h-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxamid und dessen salzen Withdrawn EP2900658A4 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
IN4014CH2012		2012-09-27
IN4629CH2012		2012-11-06
IN5296CH2012		2012-12-18
PCT/IN2013/000580 WO2014049612A2 (en)	2012-09-27	2013-09-26	Processes and polymorphs of 5-[4-[4-(5-cyano-1h-indol-3-yl) butyl]-1-piperazinyl]-2-benzofuran carboxamide and its salts

Publications (2)

Publication Number	Publication Date
EP2900658A2 EP2900658A2 (de)	2015-08-05
EP2900658A4 true EP2900658A4 (de)	2016-07-13

Family

ID=50389086

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP13842370.2A Withdrawn EP2900658A4 (de)	2012-09-27	2013-09-26	Verfahren und polymorphe von 5-[4-[4-(5-cyano-1h-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxamid und dessen salzen

Country Status (2)

Country	Link
EP (1)	EP2900658A4 (de)
WO (1)	WO2014049612A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2014040164A1 (en)	2012-09-12	2014-03-20	Apotex Pharmachem Inc.	Processes for the preparation of 3-alkyl indoles
WO2016128987A1 (en) *	2015-02-13	2016-08-18	Harman Finochem Limited	A process for preparation of 2-benzofurancarboxamide, 5-[4-[4-(5cyano-1h-indol-3-yl)butyl]-1-piperazinyl] free base and its hydrochloride salt
CN105541811A (zh) *	2016-01-08	2016-05-04	万特制药(海南)有限公司	一种抗抑郁药物维拉佐酮的精制方法
CN106518853A (zh) *	2016-09-22	2017-03-22	北京万全德众医药生物技术有限公司	一种盐酸维拉佐酮杂质的制备方法
WO2023173182A1 (pt) *	2022-03-16	2023-09-21	Eurofarma Laboratórios S.A.	Sal de docusato de vilazodona, processo de obtenção, composição farmacêutica e uso

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002102794A2 (en) *	2001-06-19	2002-12-27	Merck Patent Gmbh	Polymorphic forms of 1-'4-(5-cyanoindol-3-yl)butyl-4-(2-carbamoylbenzofuran-5-yl)piperazine hydrochloride
CN102219783A (zh) *	2011-05-05	2011-10-19	天津市汉康医药生物技术有限公司	盐酸维拉佐酮及其组合物
WO2013156935A1 (en) *	2012-04-16	2013-10-24	Ranbaxy Laboratories Limited	Process for the preparation of crystalline vilazodone hydrochloride

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2782912A1 (de) *	2011-11-23	2014-10-01	Assia Chemical Industries Ltd.	Feststoffformen von vilazodon und vilazodonhydrochlorid
CN102617558A (zh) *	2012-03-26	2012-08-01	上海泛凯生物医药科技有限公司	一种维拉佐酮的制备方法
CN102977083A (zh) *	2012-12-17	2013-03-20	南京海纳医药科技有限公司	1-[4-(5-氰基吲哚-3-基)丁基]-4-(2-氨甲酰-苯并呋喃-5-基)-哌嗪盐酸盐的新晶型xⅶ及其制备方法

2013
- 2013-09-26 EP EP13842370.2A patent/EP2900658A4/de not_active Withdrawn
- 2013-09-26 WO PCT/IN2013/000580 patent/WO2014049612A2/en not_active Ceased

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002102794A2 (en) *	2001-06-19	2002-12-27	Merck Patent Gmbh	Polymorphic forms of 1-'4-(5-cyanoindol-3-yl)butyl-4-(2-carbamoylbenzofuran-5-yl)piperazine hydrochloride
CN102219783A (zh) *	2011-05-05	2011-10-19	天津市汉康医药生物技术有限公司	盐酸维拉佐酮及其组合物
WO2013156935A1 (en) *	2012-04-16	2013-10-24	Ranbaxy Laboratories Limited	Process for the preparation of crystalline vilazodone hydrochloride

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CAIRA: "Crystalline Polymorphism of Organic Compounds", TOPICS IN CURRENT CHEMISTRY, SPRINGER, BERLIN, DE, vol. 198, 1 January 1998 (1998-01-01), pages 163 - 208, XP008166276, ISSN: 0340-1022 *
DATABASE WPI Week 201232, Derwent World Patents Index; AN 2011-P35968 [32], XP002754050 *

Also Published As

Publication number	Publication date
WO2014049612A2 (en)	2014-04-03
EP2900658A2 (de)	2015-08-05
WO2014049612A3 (en)	2014-05-22

Similar Documents

Publication	Publication Date	Title
CY2023023I1 (el)	2024-02-16	Παραγωγα λακταμης χρησιμα ως αναστολεις μεταλλαγμενης idh1
CY2021010I2 (el)	2021-06-25	4-ιμιδαζοπυριδαζιν-1-υλ-βενζαμιδια και 4-ιμιδαζοτριαζιν-1-υλ-βενζαμιδια ως αναστολεις βτκ
CY2022018I2 (el)	2023-01-05	Κρυσταλλικες μορφες αναστολεα προλυλο υδροξυλασης
SMT201700052B (it)	2017-03-08	2-(azaindol-2-il)benzimidazoli come inibitori di pad4
LT2782570T (lt)	2020-01-10	Gliutaminazės heterocikliniai inhibitoriai
SMT201600311B (it)	2016-11-10	Inibitori di cdk
SMT201700109B (it)	2017-03-08	Inibitori di istone demetilasi
PL2872488T3 (pl)	2019-01-31	Postacie krystaliczne inhibitora hydroksylazy prolilowej
DK2920168T3 (da)	2021-10-18	Heterocykliske glutaminase-inhibitorer
PT2909204T (pt)	2019-03-21	Inibidores de gsk3 e métodos de utilização dos mesmos
SMT201600238B (it)	2016-08-31	Inibitori di protein chinasi
DK2885010T3 (da)	2020-02-03	Fremgangsmåder til behandling med tauopati
CO6960542A2 (es)	2014-05-30	Polimorfos de inhibidores de cinasas
PL2831279T3 (pl)	2023-12-04	Szybkie wykrywanie aneuploidii
IL230580A0 (en)	2014-03-31	Polymorphic forms of compounds as prolyl hydroxylase inhibitor, and uses thereof
EP2912019A4 (de)	2016-04-20	Heteroaryl-hemmer von pde4
EP2683693A4 (de)	2014-10-08	Ror-gamma-t-hemmer
HUE042654T2 (hu)	2019-07-29	Eljárás genetikai variációk nem-invazív megállapítására
PT2788767T (pt)	2017-12-06	Método de detecção de adutos de nucleosoma
EP2769017A4 (de)	2015-06-03	Verfahren zur rattererkennung mit frühwarnung und anlagenschutzverwaltung
SMT201600272B (it)	2016-08-31	Diidropiridinoni e piperidinoni arilici come inibitori di mgat2
DK3409278T3 (da)	2020-11-09	Heterocykliske proteinkinaseinhibitorer
DK3461825T3 (da)	2023-08-14	Nye heterocykliske derivater samt deres anvendelser
IL247640B (en)	2021-01-31	Heteroarylpiperidine derivatives
EP2729829A4 (de)	2015-04-22	Radionukliderkennung und -identifikation

Legal Events

Date	Code	Title	Description
2015-07-03	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2015-08-05	17P	Request for examination filed	Effective date: 20150424
2015-08-05	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2015-08-05	AX	Request for extension of the european patent	Extension state: BA ME
2016-01-06	DAX	Request for extension of the european patent (deleted)
2016-03-23	RIC1	Information provided on ipc code assigned before grant	Ipc: C07D 209/10 20060101ALI20160212BHEP Ipc: C07D 405/12 20060101AFI20160212BHEP Ipc: A61K 31/496 20060101ALI20160212BHEP
2016-07-13	A4	Supplementary search report drawn up and despatched	Effective date: 20160610
2016-07-13	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 31/496 20060101ALI20160606BHEP Ipc: C07D 209/10 20060101ALI20160606BHEP Ipc: C07D 405/12 20060101AFI20160606BHEP
2017-05-16	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: EXAMINATION IS IN PROGRESS
2017-06-07	17Q	First examination report despatched	Effective date: 20170508
2018-01-19	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2018-02-21	18D	Application deemed to be withdrawn	Effective date: 20170919