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EP1846411A4 - Agents antibacteriens - Google Patents

Agents antibacteriens

Info

Publication number
EP1846411A4
EP1846411A4 EP06733883A EP06733883A EP1846411A4 EP 1846411 A4 EP1846411 A4 EP 1846411A4 EP 06733883 A EP06733883 A EP 06733883A EP 06733883 A EP06733883 A EP 06733883A EP 1846411 A4 EP1846411 A4 EP 1846411A4
Authority
EP
European Patent Office
Prior art keywords
antibacterial agents
antibacterial
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06733883A
Other languages
German (de)
English (en)
Other versions
EP1846411A2 (fr
Inventor
William Henry Miller
Meagan B Rouse
Mark Andrew Seefeld
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of EP1846411A2 publication Critical patent/EP1846411A2/fr
Publication of EP1846411A4 publication Critical patent/EP1846411A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EP06733883A 2005-01-25 2006-01-24 Agents antibacteriens Withdrawn EP1846411A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64681305P 2005-01-25 2005-01-25
PCT/US2006/002617 WO2006081289A2 (fr) 2005-01-25 2006-01-24 Agents antibacteriens

Publications (2)

Publication Number Publication Date
EP1846411A2 EP1846411A2 (fr) 2007-10-24
EP1846411A4 true EP1846411A4 (fr) 2010-08-04

Family

ID=36741017

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06733883A Withdrawn EP1846411A4 (fr) 2005-01-25 2006-01-24 Agents antibacteriens

Country Status (4)

Country Link
US (2) US7511035B2 (fr)
EP (1) EP1846411A4 (fr)
JP (1) JP2008528604A (fr)
WO (1) WO2006081289A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
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JP2008528587A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
DE602007009205D1 (de) 2006-04-06 2010-10-28 Glaxo Group Ltd Pyrrolochinoxalinonderivate als antibakterielle mittel
AU2007333115B2 (en) 2006-12-12 2013-01-10 Gilead Sciences, Inc. Composition for treating a pulmonary hypertension
CL2008001002A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
SI2137196T1 (sl) * 2007-04-20 2011-01-31 Glaxo Group Ltd Glaxo Welcome House Tricikliäśne spojine, ki vsebujejo duĺ ik, uporabne kot antibakterijska sredstva
EP2080761A1 (fr) 2008-01-18 2009-07-22 Glaxo Group Limited Composés
US8492550B2 (en) * 2008-03-07 2013-07-23 Bristol-Myers Squibb Company Hydroxyalkanyl amides as modulators of chemokine receptor activity
MX2011000755A (es) * 2008-07-28 2011-02-24 Hoffmann La Roche Derivados de diazepan y piperazina moduladores de receptores de quimiocina.
WO2010043714A1 (fr) 2008-10-17 2010-04-22 Glaxo Group Limited Composés azotés tricycliques utilisés comme agents antibactériens
JP5653935B2 (ja) 2009-01-15 2015-01-14 グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ 抗菌薬として有用なナフチリジン―２（１ｈ）−オン化合物
TWI526437B (zh) * 2011-09-09 2016-03-21 台灣神隆股份有限公司 卡巴他賽之結晶型
AR090844A1 (es) 2012-04-27 2014-12-10 Actelion Pharmaceuticals Ltd Proceso para elaborar derivados de naftiridina
AR096135A1 (es) 2013-05-02 2015-12-09 Actelion Pharmaceuticals Ltd Derivados de la quinolona
MX2017002321A (es) 2014-08-22 2017-08-02 Glaxosmithkline Ip Dev Ltd Compuestos que contienen nitrogeno triciclico para tratar infeccion por neisseria gonorrhoeae.
MA41168A (fr) * 2014-12-17 2017-10-24 Acraf Nouveaux composés antibactériens
MX2018004774A (es) 2015-10-23 2018-05-30 Esteve Labor Dr Derivados de morfolina sustituidos que tienen actividad contra el dolor.
WO2018234184A1 (fr) 2017-06-22 2018-12-27 Bayer Aktiengesellschaft Procédé de préparation de quinoléines 2,3,4-trisubstituées
WO2024020068A1 (fr) * 2022-07-19 2024-01-25 Ohio State Innovation Foundation Inhibiteurs de topoisomérase bactérienne

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004087145A2 (fr) * 2003-03-27 2004-10-14 Glaxo Group Limited Agents antibacteriens

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AU634561B2 (en) 1989-07-27 1993-02-25 Eli Lilly And Company Naphthyridine derivatives
DE4425146A1 (de) * 1994-07-15 1996-01-18 Basf Ag Verwendung heterocyclischer Verbindungen
CA2216564A1 (fr) 1995-03-29 1996-10-03 Merck & Co., Inc. Inhibiteurs de farnesyl-proteine transferase
US5534537A (en) * 1995-03-29 1996-07-09 Merck & Co., Inc. Prodrugs of inhibitors of farnesyl-protein transferase
JPH08337569A (ja) 1995-06-15 1996-12-24 Sankyo Co Ltd 鎮痛活性物質
DE19600934A1 (de) * 1996-01-12 1997-07-17 Basf Ag Substituierte Aza- und Diazacycloheptan- und Cyclooctanverbindungen und deren Verwendung
US6602864B1 (en) 1996-12-13 2003-08-05 Aventis Pharma Deutschland Gmbh Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds
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GB9822440D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
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WO2000035889A1 (fr) 1998-12-11 2000-06-22 Sankyo Company, Limited Benzylamines substituees
EP1144404A1 (fr) 1999-01-20 2001-10-17 Smithkline Beecham Plc Piperidinylquinolines utilisees comme inhibiteurs de la proteine tyrosine kinase
GB9914486D0 (en) * 1999-06-21 1999-08-18 Smithkline Beecham Plc Medicaments
TR200002099A2 (tr) * 1999-07-22 2001-06-21 Sankyo Company Limited Siklobüten türevleri, bunların hazırlanması ve terapötik kullanımları
GB9917406D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB9917408D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
US6403610B1 (en) * 1999-09-17 2002-06-11 Aventis Pharma S.A. Quinolylpropylpiperidine derivatives, their preparation and the compositions which comprise them
JP2003513092A (ja) * 1999-11-05 2003-04-08 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーション・シヤンテイフイツク・（エス．セー．エール．アー．エス） 新規複素環化合物及びその医薬としての使用
JP2001354563A (ja) 2000-06-09 2001-12-25 Sankyo Co Ltd 置換ベンジルアミン類を含有する医薬
ATE348826T1 (de) 2000-07-26 2007-01-15 Smithkline Beecham Plc Aminopiperidin chinoline und ihre azaisosteren analoga mit antibakterieller wirkung
US20040053928A1 (en) 2000-09-21 2004-03-18 Davies David Thomas Quinoline derivatives as antibacterials
US6642252B2 (en) 2000-11-07 2003-11-04 Bristol-Myers Squibb Company Acid derivatives useful as serine protease inhibitors
US6603005B2 (en) * 2000-11-15 2003-08-05 Aventis Pharma S.A. Heterocyclylalkylpiperidine derivatives, their preparation and compositions containing them
CA2430037A1 (fr) 2000-11-20 2002-05-30 Michael S. South Aryl-et-heteroaryl-pyridines polycycliques substituees utiles dans l'inhibition selective de la cascade de la coagulation
GB0031086D0 (en) 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0031088D0 (en) 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
WO2002051396A1 (fr) 2000-12-26 2002-07-04 Sankyo Company, Limited Compositions pharmaceutiques contenant des derives de cyclobutene
DE10102322A1 (de) 2001-01-19 2002-07-25 Merck Patent Gmbh Phenylderivate
GB0101577D0 (en) * 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
EP1363890A4 (fr) 2001-02-07 2009-06-10 Ore Pharmaceuticals Inc Composes de liaison au recepteur de la melanocortine-4 et procedes d'utilisation de tels composes
DE10110325A1 (de) 2001-03-03 2002-09-05 Merck Patent Gmbh Phenylderivate 2
US6602884B2 (en) * 2001-03-13 2003-08-05 Aventis Pharma S.A. Quinolylpropylpiperidine derivatives, their preparation, and compositions containing them
WO2002088107A1 (fr) * 2001-04-26 2002-11-07 Eisai Co., Ltd. Compose azote a anneaux condenses possedant un groupe pyrazolyle et servant de substituant, et composition medicale le comprenant
GB0112836D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
TW200406410A (en) 2002-01-29 2004-05-01 Glaxo Group Ltd Compounds
JP4508650B2 (ja) 2002-01-29 2010-07-21 グラクソ グループ リミテッド アミノピペリジン化合物、当該化合物の製法および当該化合物を含有する医薬組成物
US6995144B2 (en) * 2002-03-14 2006-02-07 Eisai Co., Ltd. Nitrogen containing heterocyclic compounds and medicines containing the same
TW200406413A (en) 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
AR040336A1 (es) * 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
FR2844268B1 (fr) * 2002-09-11 2004-10-22 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent
FR2844270B1 (fr) * 2002-09-11 2006-05-19 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur procede et intermediaires de preparation et les compositions qui les contiennent
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US7160888B2 (en) 2003-08-22 2007-01-09 Warner Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
JP2008528587A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004087145A2 (fr) * 2003-03-27 2004-10-14 Glaxo Group Limited Agents antibacteriens

Also Published As

Publication number Publication date
EP1846411A2 (fr) 2007-10-24
US20090181955A1 (en) 2009-07-16
US20080139539A1 (en) 2008-06-12
JP2008528604A (ja) 2008-07-31
US7759340B2 (en) 2010-07-20
US7511035B2 (en) 2009-03-31
WO2006081289A2 (fr) 2006-08-03
WO2006081289A3 (fr) 2006-12-14

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20070731

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AX Request for extension of the european patent

Extension state: HR

RAX Requested extension states of the european patent have changed

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A4 Supplementary search report drawn up and despatched

Effective date: 20100701

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20110201