EP1060243A4 - EMBRYONIC CELL LINES OR STEM CELL-SIMILAR CELL LINES PRODUCED BY CORE TRANSPLANT BETWEEN DIFFERENT SPECIES - Google Patents

EMBRYONIC CELL LINES OR STEM CELL-SIMILAR CELL LINES PRODUCED BY CORE TRANSPLANT BETWEEN DIFFERENT SPECIES

Info

Publication number: EP1060243A4
Authority: EP; European Patent Office
Prior art keywords: cell lines; transplant; core; different species; embryonic
Prior art date: 1998-03-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP99911062A

Other languages

German (de)

French (fr)

Other versions

EP1060243A1 (en

Inventor

James Robl

Jose Cibelli

Steven L Stice

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University of Massachusetts Boston

University of Massachusetts Amherst

Original Assignee

University of Massachusetts Boston

University of Massachusetts Amherst

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-02

Filing date

1999-03-02

Publication date

2005-03-09

1999-03-02 Application filed by University of Massachusetts Boston, University of Massachusetts Amherst filed Critical University of Massachusetts Boston

2000-12-20 Publication of EP1060243A1 publication Critical patent/EP1060243A1/en

2005-03-09 Publication of EP1060243A4 publication Critical patent/EP1060243A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2517/00—Cells related to new breeds of animals
- C12N2517/04—Cells produced using nuclear transfer

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Wood Science & Technology (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Developmental Biology & Embryology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

EP99911062A 1998-03-02 1999-03-02 EMBRYONIC CELL LINES OR STEM CELL-SIMILAR CELL LINES PRODUCED BY CORE TRANSPLANT BETWEEN DIFFERENT SPECIES Withdrawn EP1060243A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US3294598A	1998-03-02	1998-03-02
US32945		1998-03-02
PCT/US1999/004608 WO1999045100A1 (en)	1998-03-02	1999-03-02	Embryonic or stem-like cell lines produced by cross-species nuclear transplantation

Publications (2)

Publication Number	Publication Date
EP1060243A1 EP1060243A1 (en)	2000-12-20
EP1060243A4 true EP1060243A4 (en)	2005-03-09

Family

ID=21867727

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP99911062A Withdrawn EP1060243A4 (en)	1998-03-02	1999-03-02	EMBRYONIC CELL LINES OR STEM CELL-SIMILAR CELL LINES PRODUCED BY CORE TRANSPLANT BETWEEN DIFFERENT SPECIES

Country Status (9)

Country	Link
EP (1)	EP1060243A4 (en)
JP (1)	JP2002505100A (en)
CN (1)	CN1299408A (en)
AU (1)	AU759322B2 (en)
BR (1)	BR9908499A (en)
CA (1)	CA2323094A1 (en)
IL (1)	IL138201A0 (en)
NZ (1)	NZ506808A (en)
WO (1)	WO1999045100A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2384413A1 (en) *	1999-09-14	2001-03-22	James Robl	Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions
AU782385B2 (en) *	1999-10-15	2005-07-21	Advanced Cell Technology, Inc.	Methods of producing differentiated progenitor cells and lineage-defective embryonic stem cells
JP2004500066A (en) *	1999-12-20	2004-01-08	ユニバシティ　オブ　マサチューセッツ、ア　パブリック　インスチチユーション　オブ　ハイアー　エデュケイション　オブ　ザ　コモンウエルス　オブ　マサチューセッツ、アズ　リプリゼンテッド　バイ　イッツ　ア	Embryo or stem-like cells generated by xenogeneic nuclear transfer
US6921665B2 (en)	2000-11-27	2005-07-26	Roslin Institute (Edinburgh)	Selective antibody targeting of undifferentiated stem cells
US6576464B2 (en) *	2000-11-27	2003-06-10	Geron Corporation	Methods for providing differentiated stem cells
WO2002062131A2 (en) *	2001-02-02	2002-08-15	Infigen, Inc.	Method of cloning transgenic mammalian animals using pseudonuclei
HUP0401692A3 (en) *	2001-11-06	2005-02-28	Sheng Huizhen	Preparing somatic embryo by utilizing rabbit oocyte
CN1284851C (en)	2001-11-06	2006-11-15	上海第二医科大学	Embryonic stem cells of somatic origin and their differentiated cells
CA2480802A1 (en) *	2002-04-01	2003-10-16	Gtc Biotherapeutics, Inc.	A method for selecting cell lines to be used for nuclear transfer in mammalian species
US9719068B2 (en)	2010-05-06	2017-08-01	Children's Hospital Medical Center	Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
WO2013010045A1 (en)	2011-07-12	2013-01-17	Biotime Inc.	Novel methods and formulations for orthopedic cell therapy
WO2013177228A1 (en) *	2012-05-22	2013-11-28	Loma Linda University	Generation of integration/transgene-free stem cells
CN106661548B (en)	2014-05-28	2020-12-11	儿童医院医疗中心	Methods and systems for converting precursor cells to gastric tissue via directed differentiation
JP7248586B2 (en)	2017-04-14	2023-03-29	チルドレンズホスピタルメディカルセンター	Multi-Donor Stem Cell Compositions and Methods of Making Them
JP2020536529A (en)	2017-10-10	2020-12-17	チルドレンズホスピタルメディカルセンター	Esophageal tissue and / or organ composition and how to make it

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997037009A1 (en) *	1996-04-01	1997-10-09	University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, Represented By Its Amherst Campus	Cultured inner cell mass cell lines derived from ungulate embryos
WO1998007841A1 (en) *	1996-08-19	1998-02-26	University Of Massachusetts	Embryonic or stem-like cell lines produced by cross species nuclear transplantation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR9808192A (en) *	1997-03-06	2000-10-24	Infigen Inc	Animal cloning process
AU8587598A (en) *	1997-07-26	1999-02-16	Wisconsin Alumni Research Foundation	Trans-species nuclear transfer

1999
- 1999-03-02 CA CA002323094A patent/CA2323094A1/en not_active Abandoned
- 1999-03-02 NZ NZ506808A patent/NZ506808A/en unknown
- 1999-03-02 JP JP2000534632A patent/JP2002505100A/en active Pending
- 1999-03-02 AU AU29795/99A patent/AU759322B2/en not_active Ceased
- 1999-03-02 CN CN99805691A patent/CN1299408A/en active Pending
- 1999-03-02 IL IL13820199A patent/IL138201A0/en not_active IP Right Cessation
- 1999-03-02 BR BR9908499-6A patent/BR9908499A/en not_active Application Discontinuation
- 1999-03-02 EP EP99911062A patent/EP1060243A4/en not_active Withdrawn
- 1999-03-02 WO PCT/US1999/004608 patent/WO1999045100A1/en active IP Right Grant

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997037009A1 (en) *	1996-04-01	1997-10-09	University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, Represented By Its Amherst Campus	Cultured inner cell mass cell lines derived from ungulate embryos
WO1998007841A1 (en) *	1996-08-19	1998-02-26	University Of Massachusetts	Embryonic or stem-like cell lines produced by cross species nuclear transplantation

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ARSENIAN S ET AL: "SERUM RESPONSE FACTOR IS ESSENTIAL FOR MESODERM FORMATION DURING MOUSE EMBRYOGENESIS", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 17, no. 21, 2 November 1998 (1998-11-02), pages 6289 - 6299, XP002149683, ISSN: 0261-4189 *
BAGUTTI C, WOBUS AM, FASSLER R, WATT FM.: "Differentiation of embryonal stem cells into keratinocytes: comparison of wild-type and beta 1 integrin-deficient cells.", DEV BIOL., vol. 179, no. 1, 10 October 1996 (1996-10-10), pages 184 - 196, XP002298856 *
ROHWEDEL J ET AL: "Loss of beta-1 integrin function results in a retardation of myogenic, but an acceleration of neuronal, differentiation of embryonic stem cells in vitro", DEVELOPMENTAL BIOLOGY, ACADEMIC PRESS, NEW YORK, NY, US, vol. 201, 1998, pages 167 - 184, XP002963055, ISSN: 0012-1606 *
See also references of WO9945100A1 *

Also Published As

Publication number	Publication date
CA2323094A1 (en)	1999-09-10
WO1999045100A1 (en)	1999-09-10
BR9908499A (en)	2001-12-26
AU2979599A (en)	1999-09-20
JP2002505100A (en)	2002-02-19
EP1060243A1 (en)	2000-12-20
NZ506808A (en)	2003-12-19
IL138201A0 (en)	2001-10-31
CN1299408A (en)	2001-06-13
AU759322B2 (en)	2003-04-10

Publication	Publication Date	Title
EP0934403A4 (en)	2001-03-14	EMBRYONIC CELL LINES OR STEM CELL-LIKE CELL LINES PRODUCED BY NUCLEAR TRANSPLANTATION BETWEEN DIFFERENT SPECIES.
EP1060243A4 (en)	2005-03-09	EMBRYONIC CELL LINES OR STEM CELL-SIMILAR CELL LINES PRODUCED BY CORE TRANSPLANT BETWEEN DIFFERENT SPECIES
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Legal Events

Date	Code	Title	Description
2000-11-03	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2000-12-20	17P	Request for examination filed	Effective date: 20000921
2000-12-20	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2001-01-24	RIN1	Information on inventor provided before grant (corrected)	Inventor name: STICE, STEVEN, L. Inventor name: CIBELLI, JOSE Inventor name: ROBL, JAMES
2004-12-01	RIC1	Information provided on ipc code assigned before grant	Ipc: 7C 12N 5/16 B Ipc: 7C 12N 15/00 B Ipc: 7A 01K 67/027 A
2005-03-09	A4	Supplementary search report drawn up and despatched	Effective date: 20050124
2005-07-20	17Q	First examination report despatched	Effective date: 20050606
2006-08-02	17Q	First examination report despatched	Effective date: 20050606
2006-09-13	RIN1	Information on inventor provided before grant (corrected)	Inventor name: STICE, STEVEN, L. Inventor name: CIBELLI, JOSE Inventor name: ROBL, JAMES
2006-09-27	RIN1	Information on inventor provided before grant (corrected)	Inventor name: STICE, STEVEN, L. Inventor name: CIBELLI, JOSE Inventor name: ROBL, JAMES
2010-03-05	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2010-04-07	18D	Application deemed to be withdrawn	Effective date: 20091001