EP0830375A4 - Human inhibitor of apoptosis gene 1 - Google Patents
Human inhibitor of apoptosis gene 1Info
- Publication number
- EP0830375A4 EP0830375A4 EP95919804A EP95919804A EP0830375A4 EP 0830375 A4 EP0830375 A4 EP 0830375A4 EP 95919804 A EP95919804 A EP 95919804A EP 95919804 A EP95919804 A EP 95919804A EP 0830375 A4 EP0830375 A4 EP 0830375A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- apoptosis gene
- human inhibitor
- inhibitor
- human
- apoptosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002220670A CA2220670A1 (en) | 1995-05-11 | 1995-05-11 | Human inhibitor of apoptosis gene 1 |
PCT/US1995/005922 WO1996035703A1 (en) | 1995-05-11 | 1995-05-11 | Human inhibitor of apoptosis gene 1 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0830375A1 EP0830375A1 (en) | 1998-03-25 |
EP0830375A4 true EP0830375A4 (en) | 2001-11-21 |
Family
ID=25679809
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP95919804A Withdrawn EP0830375A4 (en) | 1995-05-11 | 1995-05-11 | Human inhibitor of apoptosis gene 1 |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0830375A4 (en) |
AU (1) | AU2548095A (en) |
CA (1) | CA2220670A1 (en) |
WO (1) | WO1996035703A1 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6156535A (en) | 1995-08-04 | 2000-12-05 | University Of Ottawa | Mammalian IAP gene family, primers, probes, and detection methods |
AUPN727595A0 (en) * | 1995-12-22 | 1996-01-18 | Walter And Eliza Hall Institute Of Medical Research, The | Therapeutic compositions |
US6133437A (en) * | 1997-02-13 | 2000-10-17 | Apoptogen, Inc. | Modulation of IAPs for the treatment of proliferative diseases |
AU5065098A (en) * | 1996-11-15 | 1998-06-10 | University Of Ottawa | Modulators of ovarial apoptosis related to iap |
US6472172B1 (en) * | 1998-07-31 | 2002-10-29 | Schering Aktiengesellschaft | DNA encoding a novel human inhibitor-of-apoptosis protein |
CA2348705A1 (en) * | 1998-10-30 | 2000-05-11 | University Of Nebraska-Lincoln | Trans-species transfer of apoptotic genes and transgenic plants developed thereby |
WO2000077201A1 (en) * | 1999-06-15 | 2000-12-21 | Astrazeneca Ab | Livin; inhibitor-of-apoptosis protein-3 (iap-3) |
EP1490490B1 (en) | 2002-03-27 | 2009-05-13 | Aegera Therapeutics Inc. | Antisense iap nucleobase oligomers and uses thereof |
US8012944B2 (en) | 2003-10-30 | 2011-09-06 | Pharmascience Inc. | Method for treating cancer using IAP antisense oligomer and chemotherapeutic agent |
-
1995
- 1995-05-11 EP EP95919804A patent/EP0830375A4/en not_active Withdrawn
- 1995-05-11 AU AU25480/95A patent/AU2548095A/en not_active Abandoned
- 1995-05-11 WO PCT/US1995/005922 patent/WO1996035703A1/en not_active Application Discontinuation
- 1995-05-11 CA CA002220670A patent/CA2220670A1/en not_active Abandoned
Non-Patent Citations (8)
Title |
---|
DUCKETT C S ET AL: "A CONSERVED FAMILY OF CELLULAR GENES RELATED TO THE BACULOVIRUS IAP GENE AND ENCODING APOPTOSIS INHIBITORS", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 15, no. 11, 1996, pages 2685 - 2694, XP002032297, ISSN: 0261-4189 * |
LISTON P ET AL: "SUPPRESSION OF APOPTOSIS IN MAMMALIAN CELLS BY NAIP AND A RELATED FAMILY OF IAP GENES", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 379, no. 6563, 25 January 1996 (1996-01-25), pages 349 - 353, XP002032296, ISSN: 0028-0836 * |
RAJCAN-SEPAROVIC ET AL: "Assignment of human inhibitor of apoptosis protein (IAP) genes xiap, hiap-1, and hiap-2 to chromosomes Xq25 and 11q22-q23 by fluorescence in situ hybridization", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 37, no. 3, 1 November 1996 (1996-11-01), pages 404 - 406, XP002121939, ISSN: 0888-7543 * |
ROTHE M ET AL: "THE TNFR2-TRAF SIGNALING COMPLEX CONTAINS TWO NOVEL PROTEINS RELATED TO BACULOVIRAL INHIBITOR OF APOPTOSIS PROTEINS", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 83, no. 7, 29 December 1995 (1995-12-29), pages 1243 - 1252, XP002032302, ISSN: 0092-8674 * |
ROY N ET AL: "THE GENE FOR NEURONAL APOPTOSIS INHIBITORY PROTEIN IS PARTIALLY DELETED IN INDIVIDUALS WITH SPINAL MUSCULAR ATROPHY", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 80, no. 1, 13 January 1995 (1995-01-13), pages 167 - 178, XP002032295, ISSN: 0092-8674 * |
See also references of WO9635703A1 * |
UREN A G ET AL: "CLONING AND EXPRESSION O FAPOPTOSIS INHIBITORY PROTEIN HOMOLOGS THAT FUNCTION TO INHIBIT APOPTOSIS AND/OR BIND TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED FACTORS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, May 1996 (1996-05-01), pages 4974 - 4978, XP000918891, ISSN: 0027-8424 * |
VAUX D L: "TOWARD AN UNDERSTANDING OF THE MOLECULAR MECHANISMS OF PHYSIOLOGICAL CELL DEATH", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 90, February 1993 (1993-02-01), pages 786 - 789, XP000918873, ISSN: 0027-8424 * |
Also Published As
Publication number | Publication date |
---|---|
EP0830375A1 (en) | 1998-03-25 |
WO1996035703A1 (en) | 1996-11-14 |
AU2548095A (en) | 1996-11-29 |
CA2220670A1 (en) | 1996-11-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19971205 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20011005 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
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17Q | First examination report despatched |
Effective date: 20030605 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20040622 |