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EP0760012A4 - Method of detecting compounds utilizing genetically modified lambdoid bacteriophage - Google Patents

Method of detecting compounds utilizing genetically modified lambdoid bacteriophage

Info

Publication number
EP0760012A4
EP0760012A4 EP94920140A EP94920140A EP0760012A4 EP 0760012 A4 EP0760012 A4 EP 0760012A4 EP 94920140 A EP94920140 A EP 94920140A EP 94920140 A EP94920140 A EP 94920140A EP 0760012 A4 EP0760012 A4 EP 0760012A4
Authority
EP
European Patent Office
Prior art keywords
genetically modified
detecting compounds
compounds utilizing
lambdoid bacteriophage
utilizing genetically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94920140A
Other languages
German (de)
French (fr)
Other versions
EP0760012A1 (en
Inventor
Bryan L Ray
Edmund C C Lin
Roberto Crea
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Symbiotech Inc
Original Assignee
Symbiotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symbiotech Inc filed Critical Symbiotech Inc
Publication of EP0760012A1 publication Critical patent/EP0760012A1/en
Publication of EP0760012A4 publication Critical patent/EP0760012A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP94920140A 1994-06-10 1994-06-10 Method of detecting compounds utilizing genetically modified lambdoid bacteriophage Withdrawn EP0760012A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1994/006543 WO1995034683A1 (en) 1994-06-10 1994-06-10 Method of detecting compounds utilizing genetically modified lambdoid bacteriophage

Publications (2)

Publication Number Publication Date
EP0760012A1 EP0760012A1 (en) 1997-03-05
EP0760012A4 true EP0760012A4 (en) 1997-07-02

Family

ID=22242658

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94920140A Withdrawn EP0760012A4 (en) 1994-06-10 1994-06-10 Method of detecting compounds utilizing genetically modified lambdoid bacteriophage

Country Status (3)

Country Link
EP (1) EP0760012A4 (en)
AU (1) AU7104294A (en)
WO (1) WO1995034683A1 (en)

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DE69129154T2 (en) * 1990-12-03 1998-08-20 Genentech, Inc., South San Francisco, Calif. METHOD FOR ENRICHING PROTEIN VARIANTS WITH CHANGED BINDING PROPERTIES
EP1100890A2 (en) 1998-07-27 2001-05-23 Genentech, Inc. Improved transformation efficiency in phage display through modification of a coat protein
EP1187914B1 (en) 1999-06-14 2005-05-25 Genentech, Inc. A structured peptide scaffold for displaying turn libraries on phage
US6914123B2 (en) 2001-04-17 2005-07-05 Genentech, Inc. Hairpin peptides with a novel structural motif and methods relating thereto
US20070160576A1 (en) 2001-06-05 2007-07-12 Genentech, Inc. IL-17A/F heterologous polypeptides and therapeutic uses thereof
KR100788092B1 (en) 2001-06-20 2007-12-21 제넨테크, 인크. Compositions and Methods for the Diagnosis and Treatment of Tumor
EP2143438B1 (en) 2001-09-18 2011-07-13 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumors
EP2067472A1 (en) 2002-01-02 2009-06-10 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
AU2003230874A1 (en) 2002-04-16 2003-11-03 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
ES2751414T5 (en) 2003-07-08 2024-04-23 Novartis Pharma Ag Antagonist antibodies to heterologous IL-17 A/F polypeptides
US7329725B1 (en) 2003-10-29 2008-02-12 Nastech Pharmaceutical Company Inc. Phage displayed Trp cage ligands
DK2161283T3 (en) 2003-11-17 2014-09-01 Genentech Inc COMPOSITIONS CONTAINING ANTIBODIES AGAINST CD79b CONJUGED TO A GROWTH INHIBITOR OR CYTOTOXIC AGENT, AND METHODS FOR TREATING TUMOR OF HEMATOPOIETIC ORIGIN
EP1869076A2 (en) 2005-03-10 2007-12-26 Genentech, Inc. Methods and compositions for modulating vascular integrity
AU2007243946B2 (en) 2006-04-05 2012-11-29 Curis, Inc. Method for using BOC/CDO to modulate hedgehog signaling
US8586006B2 (en) 2006-08-09 2013-11-19 Institute For Systems Biology Organ-specific proteins and methods of their use
EP2083017A4 (en) 2006-09-14 2011-01-12 Med & Biological Lab Co Ltd Antibody having enhanced adcc activity and method for production thereof
CA2676790A1 (en) 2007-02-22 2008-08-28 Genentech, Inc. Methods for detecting inflammatory bowel disease
KR20110038047A (en) 2008-06-20 2011-04-13 고꾸리츠 다이가꾸 호우징 오까야마 다이가꾸 Antibodies to LdL / β 2 WPI Complexes and Their Uses
US9182406B2 (en) 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
KR101151805B1 (en) 2008-10-20 2012-06-01 광주과학기술원 Bipodal Peptide Binder
US8926976B2 (en) 2009-09-25 2015-01-06 Xoma Technology Ltd. Modulators
JP5885664B2 (en) 2009-09-25 2016-03-15 ゾーマ テクノロジー リミテッド Screening method
WO2011050194A1 (en) 2009-10-22 2011-04-28 Genentech, Inc. Methods and compositions for modulating hepsin activation of macrophage-stimulating protein
CN102741294A (en) 2009-11-30 2012-10-17 霍夫曼-拉罗奇有限公司 Antibodies for the treatment and diagnosis of tumors expressing SLC34A2 (TAT211=SEQID2)
WO2011106297A2 (en) 2010-02-23 2011-09-01 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
AU2011248354A1 (en) 2010-05-03 2012-11-08 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US9428789B2 (en) 2011-03-21 2016-08-30 Biodesy, Inc. Classification of kinase inhibitors using nonlinear optical techniques
WO2013040433A1 (en) 2011-09-15 2013-03-21 Genentech, Inc. Methods of promoting differentiation
EP2766000A2 (en) 2011-10-15 2014-08-20 F.Hoffmann-La Roche Ag Scd1 antagonists for treating cancer
US20130183294A1 (en) 2012-01-18 2013-07-18 Genentech, Inc. Methods of using fgf19 modulators
RU2014133069A (en) 2012-02-11 2016-04-10 Дженентек, Инк. R-SPONDIN TRANSLOCATIONS AND WAYS WITH THEIR USE
US9139863B2 (en) 2012-03-16 2015-09-22 Genentech, Inc. Engineered conformationally-stabilized proteins
CN104254541A (en) 2012-03-16 2014-12-31 弗·哈夫曼-拉罗切有限公司 Engineered conformationally-stabilized proteins
BR112014020173A8 (en) 2012-03-16 2017-07-11 Hoffmann La Roche METHODS FOR THE TREATMENT OF A MELANOMA, USES OF AN INHIBITOR, COMPOSITIONS, KIT, METHOD OF INHIBITION, METHOD OF IDENTIFICATION, METHOD OF ADJUSTING THE TREATMENT AND INVENTION
CN106290917B (en) 2012-04-25 2020-06-05 比奥德赛公司 Method for detecting allosteric modulators of proteins
WO2013170191A1 (en) 2012-05-11 2013-11-14 Genentech, Inc. Methods of using antagonists of nad biosynthesis from nicotinamide
EP2970952B1 (en) 2013-03-14 2018-07-11 Adagene Inc. An integrated system for library construction, affinity binder screening and expression thereof
AU2014235453A1 (en) 2013-03-15 2015-10-08 Genentech, Inc. Biomarkers and methods of treating PD-1 and PD-L1 related conditions
WO2015116902A1 (en) 2014-01-31 2015-08-06 Genentech, Inc. G-protein coupled receptors in hedgehog signaling
CN106661622B (en) 2014-05-23 2020-08-21 豪夫迈·罗氏有限公司 MIT biomarkers and how to use them
CN106573961B (en) 2014-06-20 2022-01-04 豪夫迈·罗氏有限公司 CHAGASIN-based scaffold compositions, methods and uses
WO2016106286A1 (en) 2014-12-23 2016-06-30 Biodesy, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
JP6952605B2 (en) 2015-04-24 2021-10-20 ジェネンテック， インコーポレイテッド Multispecific antigen binding protein
WO2018049275A1 (en) 2016-09-09 2018-03-15 Genentech, Inc. Selective peptide inhibitors of frizzled
WO2018152496A1 (en) 2017-02-17 2018-08-23 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Compositions and methods for the diagnosis and treatment of zika virus infection
EP4230649A3 (en) 2017-04-25 2023-10-25 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Antibodies and methods for the diagnosis and treatment of epstein barr virus infection
EP3655430A1 (en) 2017-07-19 2020-05-27 The U.S.A. as represented by the Secretary, Department of Health and Human Services Antibodies and methods for the diagnosis and treatment of hepatitis b virus infection
EP3966244A1 (en) 2019-05-09 2022-03-16 F. Hoffmann-La Roche AG Methods of making antibodies

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717705A (en) * 1969-01-16 1973-02-20 M Sela Protein-bacteriophage conjugates
WO1988006630A1 (en) * 1987-03-02 1988-09-07 Genex Corporation Method for the preparation of binding molecules

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717705A (en) * 1969-01-16 1973-02-20 M Sela Protein-bacteriophage conjugates
WO1988006630A1 (en) * 1987-03-02 1988-09-07 Genex Corporation Method for the preparation of binding molecules

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
I. KATSURA.: "Mechanism of length determination in Bacteriophage Lambda tails.", ADV. BIOPHYS., vol. 26, 1990, pages 1 - 18, XP000646027 *
I.N. MARUYAMA ET AL.: "Lambda foo: a lambda phage vector for the expression of foreign proteins.", PROC. NATL. ACAD. SCI. USA, vol. 91, no. 17, August 1994 (1994-08-01), pages 8273 - 8277, XP000647491 *
N.K. ABULADZE ET AL.: "Tail length determination in bacteriophage T4", VIROLOGY, vol. 199, March 1994 (1994-03-01), pages 301 - 310, XP000647480 *
S.F. PARMLEY ET AL.: "Antibody-selectable filamentous fd phage vectors: affinity purification of target genes.", GENE, vol. 73, 1988, pages 305 - 318, XP002029963 *
See also references of WO9534683A1 *

Also Published As

Publication number Publication date
WO1995034683A1 (en) 1995-12-21
EP0760012A1 (en) 1997-03-05
AU7104294A (en) 1996-01-05

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Legal Events

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Effective date: 19980719