EP0753060A4 - Conserved t-cell receptor sequences - Google Patents

Conserved t-cell receptor sequences

Info

Publication number: EP0753060A4
Authority: EP; European Patent Office
Prior art keywords: conserved; cell receptor; receptor sequences; sequences; cell
Prior art date: 1994-04-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP95916452A

Other languages

German (de)

French (fr)

Other versions

EP0753060A1 (en

Inventor

Steven M Friedman

Mary K Crow

Yixin Li

Joseph R Tumang

Guang-Rong Sun

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

New York Society for Relief of Ruptured and Crippled

Original Assignee

New York Society for Relief of Ruptured and Crippled

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-04-18

Filing date

1995-04-14

Publication date

1999-11-24

1995-04-14 Application filed by New York Society for Relief of Ruptured and Crippled filed Critical New York Society for Relief of Ruptured and Crippled

1997-01-15 Publication of EP0753060A1 publication Critical patent/EP0753060A1/en

1999-11-24 Publication of EP0753060A4 publication Critical patent/EP0753060A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cell Biology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

EP95916452A 1994-04-18 1995-04-14 Conserved t-cell receptor sequences Withdrawn EP0753060A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US229285		1981-01-28
US22928594A	1994-04-18	1994-04-18
PCT/US1995/004803 WO1995028481A1 (en)	1994-04-18	1995-04-14	Conserved t-cell receptor sequences

Publications (2)

Publication Number	Publication Date
EP0753060A1 EP0753060A1 (en)	1997-01-15
EP0753060A4 true EP0753060A4 (en)	1999-11-24

Family

ID=22860556

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP95916452A Withdrawn EP0753060A4 (en)	1994-04-18	1995-04-14	Conserved t-cell receptor sequences

Country Status (4)

Country	Link
EP (1)	EP0753060A4 (en)
JP (1)	JPH10504181A (en)
CA (1)	CA2188182A1 (en)
WO (1)	WO1995028481A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19625191A1 (en) *	1996-06-24	1998-01-02	Boehringer Mannheim Gmbh	Renal carcinoma-specific T cells
US8691510B2 (en)	2008-11-07	2014-04-08	Sequenta, Inc.	Sequence analysis of complex amplicons
GB2497007B (en)	2008-11-07	2013-08-07	Sequenta Inc	Methods of monitoring disease conditions by analysis of the full repertoire of the V-D junction or D-J junction sequences of an individual
US9528160B2 (en)	2008-11-07	2016-12-27	Adaptive Biotechnolgies Corp.	Rare clonotypes and uses thereof
US9365901B2 (en)	2008-11-07	2016-06-14	Adaptive Biotechnologies Corp.	Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
US8748103B2 (en)	2008-11-07	2014-06-10	Sequenta, Inc.	Monitoring health and disease status using clonotype profiles
US9506119B2 (en)	2008-11-07	2016-11-29	Adaptive Biotechnologies Corp.	Method of sequence determination using sequence tags
US8628927B2 (en)	2008-11-07	2014-01-14	Sequenta, Inc.	Monitoring health and disease status using clonotype profiles
DK3059337T3 (en)	2009-01-15	2019-07-22	Adaptive Biotechnologies Corp	Adaptive immunity profiling and methods for producing monoclonal antibodies
KR20120044941A (en)	2009-06-25	2012-05-08	프레드 헛친슨 켄서 리서치 센터	Method of measuring adaptive immunity
US9043160B1 (en)	2009-11-09	2015-05-26	Sequenta, Inc.	Method of determining clonotypes and clonotype profiles
US10385475B2 (en)	2011-09-12	2019-08-20	Adaptive Biotechnologies Corp.	Random array sequencing of low-complexity libraries
AU2012325791B2 (en)	2011-10-21	2018-04-05	Adaptive Biotechnologies Corporation	Quantification of adaptive immune cell genomes in a complex mixture of cells
AU2012347460B2 (en)	2011-12-09	2017-05-25	Adaptive Biotechnologies Corporation	Diagnosis of lymphoid malignancies and minimal residual disease detection
US9499865B2 (en)	2011-12-13	2016-11-22	Adaptive Biotechnologies Corp.	Detection and measurement of tissue-infiltrating lymphocytes
ES2662128T3 (en)	2012-03-05	2018-04-05	Adaptive Biotechnologies Corporation	Determination of paired immune receptor chains from the frequency of matching subunits
WO2013169957A1 (en)	2012-05-08	2013-11-14	Adaptive Biotechnologies Corporation	Compositions and method for measuring and calibrating amplification bias in multiplexed pcr reactions
ES2749118T3 (en)	2012-10-01	2020-03-19	Adaptive Biotechnologies Corp	Assessment of immunocompetence for adaptive immunity receptor diversity and clonality characterization
US9708657B2 (en)	2013-07-01	2017-07-18	Adaptive Biotechnologies Corp.	Method for generating clonotype profiles using sequence tags
US20170292149A1 (en)	2014-03-05	2017-10-12	Adaptive Biotechnologies Corporation	Methods using randomer-containing synthetic molecules
US10066265B2 (en)	2014-04-01	2018-09-04	Adaptive Biotechnologies Corp.	Determining antigen-specific t-cells
EP3132059B1 (en)	2014-04-17	2020-01-08	Adaptive Biotechnologies Corporation	Quantification of adaptive immune cell genomes in a complex mixture of cells
ES2784343T3 (en)	2014-10-29	2020-09-24	Adaptive Biotechnologies Corp	Simultaneous, highly multiplexed detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples
US10246701B2 (en)	2014-11-14	2019-04-02	Adaptive Biotechnologies Corp.	Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
US11066705B2 (en)	2014-11-25	2021-07-20	Adaptive Biotechnologies Corporation	Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing
CA2976580A1 (en)	2015-02-24	2016-09-01	Adaptive Biotechnologies Corp.	Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing
CA2979726A1 (en)	2015-04-01	2016-10-06	Adaptive Biotechnologies Corp.	Method of identifying human compatible t cell receptors specific for an antigenic target
US10428325B1 (en)	2016-09-21	2019-10-01	Adaptive Biotechnologies Corporation	Identification of antigen-specific B cell receptors
US11254980B1 (en)	2017-11-29	2022-02-22	Adaptive Biotechnologies Corporation	Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992013949A1 (en) *	1991-02-08	1992-08-20	Roussel-Uclaf	Nucleotide sequences coding for alpha chain variable regions in human lymphocyte receptors and applications thereof
WO1993004695A1 (en) *	1991-08-28	1993-03-18	The Wistar Institute	T cell receptor-based therapy for rheumatoid arthritis
WO1993006135A1 (en) *	1991-09-23	1993-04-01	Genentech, Inc.	Diagnosing and treating autoimmune disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4886743A (en) *	1985-04-24	1989-12-12	California Institute Of Technology	Diagnostic reagents based on unique sequences within the variable region of the T cell receptor and uses thereof
US5298396A (en) *	1989-11-15	1994-03-29	National Jewish Center For Immunology And Respiratory Medicine	Method for identifying T cells disease involved in autoimmune disease

1995
- 1995-04-14 EP EP95916452A patent/EP0753060A4/en not_active Withdrawn
- 1995-04-14 JP JP7527172A patent/JPH10504181A/en active Pending
- 1995-04-14 WO PCT/US1995/004803 patent/WO1995028481A1/en not_active Application Discontinuation
- 1995-04-14 CA CA 2188182 patent/CA2188182A1/en not_active Abandoned

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992013949A1 (en) *	1991-02-08	1992-08-20	Roussel-Uclaf	Nucleotide sequences coding for alpha chain variable regions in human lymphocyte receptors and applications thereof
WO1993004695A1 (en) *	1991-08-28	1993-03-18	The Wistar Institute	T cell receptor-based therapy for rheumatoid arthritis
WO1993006135A1 (en) *	1991-09-23	1993-04-01	Genentech, Inc.	Diagnosing and treating autoimmune disorders

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
GORONZY J.J. ET AL.: "Restrictions in the repertoire of allospecific T cells.", J. IMMUNOL., vol. 151, no. 2, 15 July 1993 (1993-07-15), pages 825 - 836, XP002115157 *
JENKINS R.N. ET AL.: "T cell receptor Vb gene bias in rheumatoid arthritis", J. CLIN. INVEST., vol. 92, February 1993 (1993-02-01), pages 2688 - 2701, XP002115160 *
LI Y. ET AL: "CDR3 sequence motifs shared by oligoclonal rheumatoid arthritis synovial T cells. Evidence for an antigen-driven response.", J. CLIN. INVEST., vol. 94, no. 6, December 1994 (1994-12-01), pages 2525 - 2531, XP002115156 *
OLIVE C. ET AL.: "Analysis of T cell receptor Va and Vb gene usage in synovia of patients with rheumatoid arthritis.", IMMUNOLOGY AND CELL BIOL., vol. 69, 1991, pages 349 - 354, XP002115158 *
PLUSCHKE G. ET AL.: "Analysis of T cell receptor Vb regions expressed by rheumatoid synovial T lymphocytes.", IMMUNOBIOL., vol. 188, 1993, pages 330 - 339, XP002115159 *
See also references of WO9528481A1 *
UEMATSU Y ET AL: "THE T-CELL-RECEPTOR REPERTOIRE IN THE SYNOVIAL FLUID OF A PATIENT WITH RHEUMATOID ARTHRITIS IS POLYCLONAL", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 88, no. 19, 1 October 1991 (1991-10-01), pages 8534 - 8538, XP002062861, ISSN: 0027-8424 *

Also Published As

Publication number	Publication date
JPH10504181A (en)	1998-04-28
WO1995028481A1 (en)	1995-10-26
EP0753060A1 (en)	1997-01-15
CA2188182A1 (en)	1995-10-26

Publication	Publication Date	Title
EP0753060A4 (en)	1999-11-24	Conserved t-cell receptor sequences
GB2311853B (en)	2000-02-23	Optical gauge
IL119952A0 (en)	1997-04-15	Inertial sensor unit
GB9617923D0 (en)	1996-10-09	Novel receptor
AU134343S (en)	1998-07-13	Gauge dial
GB9701939D0 (en)	1997-03-19	Gripping arrangement for gripping casing
GB9606016D0 (en)	1996-05-22	Novel use
AU130290S (en)	1997-06-13	Gauge
AU130155S (en)	1997-06-02	Scale
GB9619577D0 (en)	1996-10-30	Retaining means
PL320747A1 (en)	1997-10-27	Novel receptor
GB9718216D0 (en)	1997-11-05	Jacknife resistant apparatus
ZA964672B (en)	1997-03-11	4-vf line multiplexer
GB9611192D0 (en)	1996-07-31	Use
GB9611256D0 (en)	1996-07-31	Diamond
GB9607711D0 (en)	1996-06-19	T-cell dependent vaccine
IL120659A0 (en)	1997-08-14	Dual advance rate grip/support device
AU134205S (en)	1998-07-01	Scale
TW349453U (en)	1999-01-01	Polished apparatus
GB9706696D0 (en)	1997-05-21	Clamp
CA79800S (en)	1997-01-17	Gauge
GB2395194B (en)	2004-09-01	Epsilon hexanthrohexaazaisowurtzitane
GB9611230D0 (en)	1996-07-31	Improved gauge
GB9717746D0 (en)	1997-10-29	Retaining unit
TW294968U (en)	1997-01-01	Wrist cushion sheath

Legal Events

Date	Code	Title	Description
1996-11-29	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1997-01-15	17P	Request for examination filed	Effective date: 19961115
1997-01-15	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1999-11-03	RIC1	Information provided on ipc code assigned before grant	Free format text: 6C 12N 15/00 A, 6C 12N 15/09 B, 6C 12N 15/11 B, 6C 12N 15/12 B, 6C 12N 15/13 B, 6C 07K 4/00 B, 6C 07K 14/00 B, 6C 07K 14/435 B, 6C 07K 14/47 B, 6C 07K 14/725 B, 6C 07K 14/705 B
1999-11-24	A4	Supplementary search report drawn up and despatched	Effective date: 19991008
1999-11-24	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
2002-03-28	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2002-05-15	18D	Application deemed to be withdrawn	Effective date: 20011101