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EP0684834A4 - Microemulsions contenant des peptides therapeutiques. - Google Patents

Microemulsions contenant des peptides therapeutiques.

Info

Publication number
EP0684834A4
EP0684834A4 EP94909810A EP94909810A EP0684834A4 EP 0684834 A4 EP0684834 A4 EP 0684834A4 EP 94909810 A EP94909810 A EP 94909810A EP 94909810 A EP94909810 A EP 94909810A EP 0684834 A4 EP0684834 A4 EP 0684834A4
Authority
EP
European Patent Office
Prior art keywords
microemulsions
therapeutic peptides
peptides
therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94909810A
Other languages
German (de)
English (en)
Other versions
EP0684834A1 (fr
Inventor
Panayiotis Peri Constantinides
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0684834A1 publication Critical patent/EP0684834A1/fr
Publication of EP0684834A4 publication Critical patent/EP0684834A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/25Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
EP94909810A 1993-02-17 1994-02-17 Microemulsions contenant des peptides therapeutiques. Withdrawn EP0684834A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1895693A 1993-02-17 1993-02-17
US18956 1993-02-17
PCT/US1994/002062 WO1994019003A1 (fr) 1993-02-17 1994-02-17 Microemulsions contenant des peptides therapeutiques

Publications (2)

Publication Number Publication Date
EP0684834A1 EP0684834A1 (fr) 1995-12-06
EP0684834A4 true EP0684834A4 (fr) 1996-09-25

Family

ID=21790620

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94909810A Withdrawn EP0684834A4 (fr) 1993-02-17 1994-02-17 Microemulsions contenant des peptides therapeutiques.

Country Status (3)

Country Link
EP (1) EP0684834A4 (fr)
JP (1) JPH08507078A (fr)
WO (1) WO1994019003A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
ATE317397T1 (de) * 1993-11-17 2006-02-15 Athena Neurosciences Inc Transparente flüssigkeit zur verabreichung von verkapselten medikamenten
EP0788346B9 (fr) * 1994-03-18 2007-02-14 Supernus Pharmaceuticals, Inc. Systemes d'administration de medicaments emulsionnes
GB9613858D0 (en) 1996-07-02 1996-09-04 Cortecs Ltd Hydrophobic preparations
DE69826847T3 (de) 1997-03-31 2010-05-12 Boston Scientific Ltd., St. Michael Verwendung von cytoskelettinhibitoren zur vorbeugung der restenose
SE9703691D0 (sv) 1997-10-10 1997-10-10 Astra Ab Pharmaceutical compositions
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
EP1498143A1 (fr) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Formulations auto-émulsifiantes et auto-microémulsifiantes pour l'administration orale de taxoides
US9028852B2 (en) 2004-09-07 2015-05-12 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
JP2011504871A (ja) * 2007-06-01 2011-02-17 ノボ・ノルデイスク・エー/エス 固体又は半固体担体中にペプチド薬剤を含む自然に分散可能なプレコンセントレイト
HUE032287T2 (en) 2008-03-18 2017-09-28 Novo Nordisk As Protease-stabilized, acylated insulin analogues
GB201107630D0 (en) * 2011-05-06 2011-06-22 Proxima Concepts Ltd Microemulsions
GB201107629D0 (en) * 2011-05-06 2011-06-22 Proxima Concepts Ltd Hydrophobic preparations
CN104364260B (zh) 2012-04-11 2017-02-22 诺和诺德股份有限公司 胰岛素制剂
WO2018109162A1 (fr) 2016-12-16 2018-06-21 Novo Nordisk A/S Compositions pharmaceutiques contenant de l'insuline
US20220117859A1 (en) * 2018-11-30 2022-04-21 3M Innovative Properties Company Topical antimicrobial microemulsions with fluorescent materials
WO2020109933A1 (fr) * 2018-11-30 2020-06-04 3M Innovative Properties Company Microémulsions antimicrobiennes topiques
TWI834862B (zh) * 2019-04-11 2024-03-11 美商R P 先靈爾科技公司 用於經口投遞滲透性不良蛋白質、肽及小分子之調配物

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
EP0278660A1 (fr) * 1987-02-03 1988-08-17 Stiefel Laboratories (Ireland) Limited Microémulsions
EP0387647A2 (fr) * 1989-03-13 1990-09-19 Desitin Arzneimittel GmbH Composition pharmaceutique à haute dispersion
WO1993002664A1 (fr) * 1991-07-26 1993-02-18 Smithkline Beecham Corporation Micro-emulsion huileuse

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110606A (en) * 1990-11-13 1992-05-05 Affinity Biotech, Inc. Non-aqueous microemulsions for drug delivery

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
EP0278660A1 (fr) * 1987-02-03 1988-08-17 Stiefel Laboratories (Ireland) Limited Microémulsions
EP0387647A2 (fr) * 1989-03-13 1990-09-19 Desitin Arzneimittel GmbH Composition pharmaceutique à haute dispersion
WO1993002664A1 (fr) * 1991-07-26 1993-02-18 Smithkline Beecham Corporation Micro-emulsion huileuse

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9419003A1 *

Also Published As

Publication number Publication date
JPH08507078A (ja) 1996-07-30
EP0684834A1 (fr) 1995-12-06
WO1994019003A1 (fr) 1994-09-01

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19950915

AK Designated contracting states

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A4 Supplementary search report drawn up and despatched

Effective date: 19960807

AK Designated contracting states

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17Q First examination report despatched

Effective date: 19990218

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19990629