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EP0356479A1 - Process for manufacturing veterinary products being suitable particularly for treatment of mastitis and the product thus obtained - Google Patents

Process for manufacturing veterinary products being suitable particularly for treatment of mastitis and the product thus obtained

Info

Publication number
EP0356479A1
EP0356479A1 EP89902276A EP89902276A EP0356479A1 EP 0356479 A1 EP0356479 A1 EP 0356479A1 EP 89902276 A EP89902276 A EP 89902276A EP 89902276 A EP89902276 A EP 89902276A EP 0356479 A1 EP0356479 A1 EP 0356479A1
Authority
EP
European Patent Office
Prior art keywords
treatment
emulsifier
milk
ointment
emulsion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP89902276A
Other languages
German (de)
English (en)
French (fr)
Inventor
Frigyes Kovacs
András LAMMEL
Geza Kubamyi
Andor Damasdi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UNIPHARMA RT
Original Assignee
UNIPHARMA RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UNIPHARMA RT filed Critical UNIPHARMA RT
Publication of EP0356479A1 publication Critical patent/EP0356479A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey

Definitions

  • the subject of the invention is a process for manufacturing veterinary products - e . g. udder infusion, ointment, emulsion , etc .
  • mastitis affects in most case s cows with big milk production which is easy to understand knowing the fact that production of 1 litre of milk requires 300 to 500 litres of blood to flow through the lactiferous gland. The new process is of great importance since mastitis
  • the yearly loss in Hungary is estimated to reach HUF 720 to 750 millions at present, the same in the USA amounts to US D 1294 millions which means a yearly loss of USD 150 to 300 per c ow, caused by mastitits.
  • the yearly loss caused by this disease in European countries is estimated as follows :
  • Garget generally decreases the total milk production by 11 % in each country. The damages are listed below:
  • gargets are highly influenced by the prevailing conditions of animal keeping, feeding and hygiene and also by the breeder of animals himself. This means that the appearance and severity of garget varies a lot with diaries and individuals - depending on the conditions mentioned.
  • the pathogens causing infection /bacteria, fungi, viruses, etc. / reach the lacteal tracks of the udder in most cases in a galactogen way and the parenchyme of the udder resp. bringing on disease of varying severity, depending on their patho genetics and resistance of the organism or udder respectively.
  • Local medical treatment is generally applied in case of disease manifesting itself by clinical symptoms .
  • the invention has the aim to provide a process to produce veterinary preparations eliminating the above mentioned disadvantage , for treatment of mastitis and the product thus obtained.
  • udder infusion of 2 decilitres meets several litres of milk in the milk pelvis of both the milkers and non-milkers
  • the received system containing complex emulsifier is to be introduced from the disposable plastic appliance into the diseased uddersection where it meets the milk and becomes activated.
  • the main point of the invention-based preparation is consequently that its active ingredient is soft propolis of 0,5 -10 v/v %
  • Paraffinum liquidum 431 0 g
  • the total weight of the components used in both cases 750,0 g .
  • Example 3 Standard propolis concentrate /soft propolis / 15 g
  • Soft propolis 0,5-10 /optimally 6/ v/v % was mixed with an indifferent solvent of hydrophilous character /propyleneglycol - polioxaeten 400/ , for practical purposes with propylenglycol .
  • the active ingredient content is bactericide , viricide and fungicide on a quite wide scale
  • the preparations have a significant antiphlogistic, local anaesthetic, epidermidalizationing and an analgetic effect;
  • the milk produced from the treated udder has no more germicidal substance content after 6 hours, thus the value of milk does not drop.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
EP89902276A 1988-02-08 1989-02-08 Process for manufacturing veterinary products being suitable particularly for treatment of mastitis and the product thus obtained Withdrawn EP0356479A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU55188 1988-02-08
HU88551A HU198843B (en) 1988-02-08 1988-02-08 Process for producing veterinary compositions with disinfecting and antiinflammatory action, comprising natural active ingredient and suitable particularly for treating mastitis

Publications (1)

Publication Number Publication Date
EP0356479A1 true EP0356479A1 (en) 1990-03-07

Family

ID=10950120

Family Applications (1)

Application Number Title Priority Date Filing Date
EP89902276A Withdrawn EP0356479A1 (en) 1988-02-08 1989-02-08 Process for manufacturing veterinary products being suitable particularly for treatment of mastitis and the product thus obtained

Country Status (11)

Country Link
EP (1) EP0356479A1 (xx)
AU (1) AU629201B2 (xx)
DD (1) DD280037A5 (xx)
DK (1) DK489989A (xx)
ES (1) ES2012675A6 (xx)
FI (1) FI894756A0 (xx)
GR (1) GR1000497B (xx)
HU (1) HU198843B (xx)
IL (1) IL89204A0 (xx)
NZ (1) NZ227957A (xx)
WO (1) WO1989006955A1 (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1075276T3 (da) * 1998-05-07 2008-02-11 Corixa Corp Adjuvanssammensætning og fremgangsmåder til dens anvendelse
DE102008034944B4 (de) * 2008-07-26 2017-03-16 Arivine Pharma Ag Mikroemulsion
CL2012002768A1 (es) 2012-10-02 2013-06-21 Consorcio De Desarrollo Tecnologico Apicola S A Solucion antiseptica para prevencion de mastitis subclinica en vacas lecheras que comprende una mezcla de propoleo y solucion de miel de abejas en proporciones desde 1:5 a 5:1, uso de la solucion antiseptica porque sirve para la profilaxis, prevencion y control de mastitis subclinica de vacas lecheras.
CN102961519B (zh) * 2012-11-22 2015-07-29 青岛绿曼生物工程有限公司 治疗奶牛乳房炎的复方蜂胶组合物及其制备方法
CN110638837B (zh) * 2019-10-31 2021-05-07 广东国源国药制药有限公司 蜂胶提取物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT167862B (de) * 1948-09-09 1951-03-10 Albin Jenko Verfahren zur Herstellung eines Kittharz (Propolis) als Wirkstoff enthaltenden Präparates zur Behandlung von Wunden, Geschwülsten und Entzündungen
FR1084006A (fr) * 1953-09-25 1955-01-14 Produit de beauté et de rajeunissement
US3049473A (en) * 1956-08-13 1962-08-14 Ici Ltd Udder-dispersible antibiotic mastitis creams
US3950554A (en) * 1974-01-31 1976-04-13 Southeastern Laboratories, Inc. Treatment of mastitis in bovine udders
EP0061508B1 (de) * 1981-03-27 1985-06-26 Rudolf Schanze Verfahren zur Gewinnung von Bienenkittharz enthaltenden Produkten und Bienenkittharz enthaltende Produkte
DE3210272A1 (de) * 1982-03-20 1983-09-29 Fa. Peter O. Glienke + Partner Industrieberatung GmbH, 7570 Baden-Baden Verfahren zum herstellen eines propolis-extraktes
DE3279437D1 (en) * 1982-12-01 1989-03-16 Zenon M Sosnowski Method for extracting propolis and water soluble dry propolis powder obtained thereby and cosmetic and pharmaceutical preparations containing same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO8906955A1 *

Also Published As

Publication number Publication date
DK489989D0 (da) 1989-10-04
AU3051689A (en) 1989-08-25
DD280037A5 (de) 1990-06-27
HU198843B (en) 1989-12-28
FI894756A (fi) 1989-10-06
IL89204A0 (en) 1989-09-10
DK489989A (da) 1989-10-04
WO1989006955A1 (en) 1989-08-10
AU629201B2 (en) 1992-10-01
NZ227957A (en) 1992-05-26
GR1000497B (el) 1992-07-30
FI894756A0 (fi) 1989-10-06
ES2012675A6 (es) 1990-04-01

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19891220

AK Designated contracting states

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17Q First examination report despatched

Effective date: 19910625

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 19930504