EP0356479A1 - Process for manufacturing veterinary products being suitable particularly for treatment of mastitis and the product thus obtained - Google Patents
Process for manufacturing veterinary products being suitable particularly for treatment of mastitis and the product thus obtainedInfo
- Publication number
- EP0356479A1 EP0356479A1 EP89902276A EP89902276A EP0356479A1 EP 0356479 A1 EP0356479 A1 EP 0356479A1 EP 89902276 A EP89902276 A EP 89902276A EP 89902276 A EP89902276 A EP 89902276A EP 0356479 A1 EP0356479 A1 EP 0356479A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- treatment
- emulsifier
- milk
- ointment
- emulsion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
Definitions
- the subject of the invention is a process for manufacturing veterinary products - e . g. udder infusion, ointment, emulsion , etc .
- mastitis affects in most case s cows with big milk production which is easy to understand knowing the fact that production of 1 litre of milk requires 300 to 500 litres of blood to flow through the lactiferous gland. The new process is of great importance since mastitis
- the yearly loss in Hungary is estimated to reach HUF 720 to 750 millions at present, the same in the USA amounts to US D 1294 millions which means a yearly loss of USD 150 to 300 per c ow, caused by mastitits.
- the yearly loss caused by this disease in European countries is estimated as follows :
- Garget generally decreases the total milk production by 11 % in each country. The damages are listed below:
- gargets are highly influenced by the prevailing conditions of animal keeping, feeding and hygiene and also by the breeder of animals himself. This means that the appearance and severity of garget varies a lot with diaries and individuals - depending on the conditions mentioned.
- the pathogens causing infection /bacteria, fungi, viruses, etc. / reach the lacteal tracks of the udder in most cases in a galactogen way and the parenchyme of the udder resp. bringing on disease of varying severity, depending on their patho genetics and resistance of the organism or udder respectively.
- Local medical treatment is generally applied in case of disease manifesting itself by clinical symptoms .
- the invention has the aim to provide a process to produce veterinary preparations eliminating the above mentioned disadvantage , for treatment of mastitis and the product thus obtained.
- udder infusion of 2 decilitres meets several litres of milk in the milk pelvis of both the milkers and non-milkers
- the received system containing complex emulsifier is to be introduced from the disposable plastic appliance into the diseased uddersection where it meets the milk and becomes activated.
- the main point of the invention-based preparation is consequently that its active ingredient is soft propolis of 0,5 -10 v/v %
- Paraffinum liquidum 431 0 g
- the total weight of the components used in both cases 750,0 g .
- Example 3 Standard propolis concentrate /soft propolis / 15 g
- Soft propolis 0,5-10 /optimally 6/ v/v % was mixed with an indifferent solvent of hydrophilous character /propyleneglycol - polioxaeten 400/ , for practical purposes with propylenglycol .
- the active ingredient content is bactericide , viricide and fungicide on a quite wide scale
- the preparations have a significant antiphlogistic, local anaesthetic, epidermidalizationing and an analgetic effect;
- the milk produced from the treated udder has no more germicidal substance content after 6 hours, thus the value of milk does not drop.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Insects & Arthropods (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Husbandry (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU55188 | 1988-02-08 | ||
HU88551A HU198843B (en) | 1988-02-08 | 1988-02-08 | Process for producing veterinary compositions with disinfecting and antiinflammatory action, comprising natural active ingredient and suitable particularly for treating mastitis |
Publications (1)
Publication Number | Publication Date |
---|---|
EP0356479A1 true EP0356479A1 (en) | 1990-03-07 |
Family
ID=10950120
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP89902276A Withdrawn EP0356479A1 (en) | 1988-02-08 | 1989-02-08 | Process for manufacturing veterinary products being suitable particularly for treatment of mastitis and the product thus obtained |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0356479A1 (xx) |
AU (1) | AU629201B2 (xx) |
DD (1) | DD280037A5 (xx) |
DK (1) | DK489989A (xx) |
ES (1) | ES2012675A6 (xx) |
FI (1) | FI894756A0 (xx) |
GR (1) | GR1000497B (xx) |
HU (1) | HU198843B (xx) |
IL (1) | IL89204A0 (xx) |
NZ (1) | NZ227957A (xx) |
WO (1) | WO1989006955A1 (xx) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1075276T3 (da) * | 1998-05-07 | 2008-02-11 | Corixa Corp | Adjuvanssammensætning og fremgangsmåder til dens anvendelse |
DE102008034944B4 (de) * | 2008-07-26 | 2017-03-16 | Arivine Pharma Ag | Mikroemulsion |
CL2012002768A1 (es) | 2012-10-02 | 2013-06-21 | Consorcio De Desarrollo Tecnologico Apicola S A | Solucion antiseptica para prevencion de mastitis subclinica en vacas lecheras que comprende una mezcla de propoleo y solucion de miel de abejas en proporciones desde 1:5 a 5:1, uso de la solucion antiseptica porque sirve para la profilaxis, prevencion y control de mastitis subclinica de vacas lecheras. |
CN102961519B (zh) * | 2012-11-22 | 2015-07-29 | 青岛绿曼生物工程有限公司 | 治疗奶牛乳房炎的复方蜂胶组合物及其制备方法 |
CN110638837B (zh) * | 2019-10-31 | 2021-05-07 | 广东国源国药制药有限公司 | 蜂胶提取物及其制备方法和应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT167862B (de) * | 1948-09-09 | 1951-03-10 | Albin Jenko | Verfahren zur Herstellung eines Kittharz (Propolis) als Wirkstoff enthaltenden Präparates zur Behandlung von Wunden, Geschwülsten und Entzündungen |
FR1084006A (fr) * | 1953-09-25 | 1955-01-14 | Produit de beauté et de rajeunissement | |
US3049473A (en) * | 1956-08-13 | 1962-08-14 | Ici Ltd | Udder-dispersible antibiotic mastitis creams |
US3950554A (en) * | 1974-01-31 | 1976-04-13 | Southeastern Laboratories, Inc. | Treatment of mastitis in bovine udders |
EP0061508B1 (de) * | 1981-03-27 | 1985-06-26 | Rudolf Schanze | Verfahren zur Gewinnung von Bienenkittharz enthaltenden Produkten und Bienenkittharz enthaltende Produkte |
DE3210272A1 (de) * | 1982-03-20 | 1983-09-29 | Fa. Peter O. Glienke + Partner Industrieberatung GmbH, 7570 Baden-Baden | Verfahren zum herstellen eines propolis-extraktes |
DE3279437D1 (en) * | 1982-12-01 | 1989-03-16 | Zenon M Sosnowski | Method for extracting propolis and water soluble dry propolis powder obtained thereby and cosmetic and pharmaceutical preparations containing same |
-
1988
- 1988-02-08 HU HU88551A patent/HU198843B/hu not_active IP Right Cessation
-
1989
- 1989-02-07 IL IL89204A patent/IL89204A0/xx unknown
- 1989-02-08 DD DD89325628A patent/DD280037A5/de not_active IP Right Cessation
- 1989-02-08 AU AU30516/89A patent/AU629201B2/en not_active Ceased
- 1989-02-08 WO PCT/HU1989/000004 patent/WO1989006955A1/en not_active Application Discontinuation
- 1989-02-08 EP EP89902276A patent/EP0356479A1/en not_active Withdrawn
- 1989-02-08 ES ES8900791A patent/ES2012675A6/es not_active Expired - Fee Related
- 1989-02-09 GR GR890100080A patent/GR1000497B/el unknown
- 1989-02-13 NZ NZ227957A patent/NZ227957A/en unknown
- 1989-10-04 DK DK489989A patent/DK489989A/da not_active Application Discontinuation
- 1989-10-06 FI FI894756A patent/FI894756A0/fi not_active IP Right Cessation
Non-Patent Citations (1)
Title |
---|
See references of WO8906955A1 * |
Also Published As
Publication number | Publication date |
---|---|
DK489989D0 (da) | 1989-10-04 |
AU3051689A (en) | 1989-08-25 |
DD280037A5 (de) | 1990-06-27 |
HU198843B (en) | 1989-12-28 |
FI894756A (fi) | 1989-10-06 |
IL89204A0 (en) | 1989-09-10 |
DK489989A (da) | 1989-10-04 |
WO1989006955A1 (en) | 1989-08-10 |
AU629201B2 (en) | 1992-10-01 |
NZ227957A (en) | 1992-05-26 |
GR1000497B (el) | 1992-07-30 |
FI894756A0 (fi) | 1989-10-06 |
ES2012675A6 (es) | 1990-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19891220 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE FR GB IT LI LU NL SE |
|
17Q | First examination report despatched |
Effective date: 19910625 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19930504 |