EP0252951A4 - Technetium-antikörper konjugate. - Google Patents

Technetium-antikörper konjugate.

Info

Publication number: EP0252951A4
Authority: EP; European Patent Office
Prior art keywords: technetium; antibody conjugate; conjugate; antibody
Prior art date: 1986-01-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP19870900623

Other languages

English (en)

French (fr)

Other versions

EP0252951A1 (de

Inventor

Ian Farquhar Campbell Mckenzie

Geoffrey Allan Pietersz

Jerry Kanellos

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University of Melbourne

Original Assignee

University of Melbourne

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-06

Filing date

1987-01-06

Publication date

1988-09-07

1987-01-06 Application filed by University of Melbourne filed Critical University of Melbourne

1988-01-20 Publication of EP0252951A1 publication Critical patent/EP0252951A1/de

1988-09-07 Publication of EP0252951A4 publication Critical patent/EP0252951A4/de

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmacology & Pharmacy (AREA)
Physics & Mathematics (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Optics & Photonics (AREA)
Immunology (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Oncology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

EP19870900623 1986-01-06 1987-01-06 Technetium-antikörper konjugate. Withdrawn EP0252951A4 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
AU4103/86		1986-01-06
AUPH410386		1986-01-06

Publications (2)

Publication Number	Publication Date
EP0252951A1 EP0252951A1 (de)	1988-01-20
EP0252951A4 true EP0252951A4 (de)	1988-09-07

Family

ID=3771433

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP19870900623 Withdrawn EP0252951A4 (de)	1986-01-06	1987-01-06	Technetium-antikörper konjugate.

Country Status (2)

Country	Link
EP (1)	EP0252951A4 (de)
WO (1)	WO1987004164A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4877868A (en) *	1986-03-12	1989-10-31	Neorx Corporation	Radionuclide antibody coupling
US5460785A (en) *	1989-08-09	1995-10-24	Rhomed Incorporated	Direct labeling of antibodies and other protein with metal ions
US5346687A (en) *	1989-08-09	1994-09-13	Rhomed Incorporated	Direct radiolabeling of antibody against stage specific embryonic antigen for diagnostic imaging
US5078985A (en) *	1989-08-09	1992-01-07	Rhomed, Incorporated	Radiolabeling antibodies and other proteins with technetium or rhenium by regulated reduction
ATE172879T1 (de) *	1989-08-09	1998-11-15	Rhomed Inc	Direkte radioetikettierung von antikörpern und sonstigen proteinen mittels technetium oder rhenium
US5326856A (en) *	1992-04-09	1994-07-05	Cytogen Corporation	Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding
US6080384A (en) *	1997-03-25	2000-06-27	American Biogenetic Sciences, Inc.	Methods for radionuclide-labeling of biomolecules and kits utilizing the same
DE19845798A1 (de) *	1998-09-29	2000-04-13	Schering Ag	Verwendung von Neoangiogenese-Markern für Diagnose und Therapie von Tumoren, diese enthaltende Mittel, sowie Verfahren zu deren Herstellung

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0028092A2 (de) *	1979-10-29	1981-05-06	University Patents, Inc.	Zusammensetzung, die einen radiomarkierten Antikörper enthält, Ausrüstung zu ihrer Herstellung und Ausrüstung zur Krebs- oder Tumorbestimmung, die diese Zusammensetzung enthält

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4323546A (en) *	1978-05-22	1982-04-06	Nuc Med Inc.	Method and composition for cancer detection in humans
US4486538A (en) *	1978-07-07	1984-12-04	Samuel Bogoch	Detection of malignant tumor cells
FR2437213A1 (fr) *	1978-09-28	1980-04-25	Cm Ind	Produits cytotoxiques formes par liaison covalente de la chaine a de la ricine avec un anticorps et leur procede de preparation
FR2516794B1 (fr) *	1981-11-20	1985-10-25	Sanofi Sa	Nouveaux medicaments anticancereux pour le traitement des leucemies t constitues de la chaine a de la ricine et d'un anticorps monoclonal specifique
FR2523445A1 (fr) *	1982-03-17	1983-09-23	Sanofi Sa	Nouveaux conjugues associant, par liaison covalente, une enzyme et un anticorps, et associations medicamenteuses utilisant lesdits conjugues
AU565669B2 (en) *	1983-12-29	1987-09-24	Commonwealth Of Australia, The	Preparation of 99m-tc radiopharmaceuticals
EP0179872B1 (de) *	1984-04-23	1991-06-19	Boston Biomedical Research Institute, Inc.	Doppelspezifische antikörper-determinanten

1987
- 1987-01-06 EP EP19870900623 patent/EP0252951A4/de not_active Withdrawn
- 1987-01-06 WO PCT/AU1987/000004 patent/WO1987004164A1/en not_active Application Discontinuation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0028092A2 (de) *	1979-10-29	1981-05-06	University Patents, Inc.	Zusammensetzung, die einen radiomarkierten Antikörper enthält, Ausrüstung zu ihrer Herstellung und Ausrüstung zur Krebs- oder Tumorbestimmung, die diese Zusammensetzung enthält

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, Vol. 104, No. 18, 5th May 1986, page 449, Abstract No. 155935y, Columbus, Ohio, US, J. BALDAS et al.: "Effect of the technetium-nitrido group on the behavior of technetium-99m-radio-pharmaceuticals". *
International Journal of Applied Radiation and Isotopes, Vol. 36, No. 2, February 1985, pages 133-139, Oxford, GB, J. BALDAS et al.: "Substitution reactions of 99mTcNC14 - a route to a new class of 99mTc-radiopharmaceuticals". *
See also references of WO8704164A1 *

Also Published As

Publication number	Publication date
WO1987004164A1 (en)	1987-07-16
EP0252951A1 (de)	1988-01-20

Publication	Publication Date	Title
DE3765969D1 (en)	1990-12-13	Thiazepinverbindungen.
DE3768161D1 (en)	1991-04-04	Acylanilidabkoemmlinge.
DE3777539D1 (en)	1992-04-23	Suessungsmittelzusammensetzung.
DE3762303D1 (en)	1990-05-23	Suessstoff.
DE3769236D1 (en)	1991-05-16	Differential-planetengetriebe.
DE3776060D1 (en)	1992-02-27	Polyphenylenaetherzusammensetzung.
DE3772064D1 (en)	1991-09-19	Porphyrinderivate.
DE3766605D1 (en)	1991-01-17	Eishockey-puck.
DE3762520D1 (en)	1990-06-07	Thienothiophenfarbstoffe.
DE3776359D1 (en)	1992-03-12	Duennschichtmagnetkopf.
EP0262876A3 (en)	1989-11-29	Nucleoside-phospholipid conjugate
DE3780383D1 (en)	1992-08-20	Polyphenyleneaetherharzzusammensetzung.
DE3779374D1 (en)	1992-07-02	Xanthinderivate.
DE3761369D1 (en)	1990-02-15	Foerderer.
DE3775342D1 (en)	1992-01-30	Fluegelzellenverdichter.
DE3768001D1 (en)	1991-03-14	Temperaturkompensierter thermodrucker.
DE3774838D1 (en)	1992-01-09	8-arylxanthine.
DE3768767D1 (en)	1991-04-25	Duennschichtmonitor.
DE3768095D1 (en)	1991-04-04	Brueckenverstaerker.
DE3767080D1 (en)	1991-02-07	Waermesensible polyurethan-dispersionen.
DE3771692D1 (en)	1991-08-29	Arbiterschaltung.
DE3773255D1 (en)	1991-10-31	Thermosensitiver widerstand.
DE3768140D1 (en)	1991-04-04	Fluegelzellenpumpe.
DE3765225D1 (en)	1990-10-31	Roentgenstrahlroehre.
DE3767912D1 (en)	1991-03-14	Erythromycin-derivate.

Legal Events

Date	Code	Title	Description
1987-12-05	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1988-01-20	17P	Request for examination filed	Effective date: 19870904
1988-01-20	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE FR GB IT LI LU NL SE
1988-10-26	A4	Supplementary search report drawn up and despatched	Effective date: 19880907
1989-04-21	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN
1989-05-31	18W	Application withdrawn	Withdrawal date: 19890407
1989-06-07	R18W	Application withdrawn (corrected)	Effective date: 19890407
2007-08-08	RIN1	Information on inventor provided before grant (corrected)	Inventor name: MCKENZIE, IAN, FARQUHAR, CAMPBELL Inventor name: KANELLOS, JERRY Inventor name: PIETERSZ, GEOFFREY, ALLAN