EG23791A - 1-(4-(1-4-Fluorophenyl-1H-indole-3-yl-1-butyl spiro (isobenzofuran 1-(3H), 4-Piperidine) hydrohalogenides - Google Patents

1-(4-(1-4-Fluorophenyl-1H-indole-3-yl-1-butyl spiro (isobenzofuran 1-(3H), 4-Piperidine) hydrohalogenides

Info

Publication number: EG23791A
Authority: EG; Egypt
Prior art keywords: hydrohalogenides; isobenzofuran; fluorophenyl; indole; piperidine
Prior art date: 1997-11-07

Application number

EG136298A

Other languages

English (en)

Inventor

Niels Mork

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-07

Filing date

1998-11-03

Publication date

2007-08-13

1998-11-03 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2007-08-13 Application granted granted Critical

2007-08-13 Publication of EG23791A publication Critical patent/EG23791A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Psychology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

EG136298A 1997-11-07 1998-11-03 1-(4-(1-4-Fluorophenyl-1H-indole-3-yl-1-butyl spiro (isobenzofuran 1-(3H), 4-Piperidine) hydrohalogenides EG23791A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK126797		1997-11-07

Publications (1)

Publication Number	Publication Date
EG23791A true EG23791A (en)	2007-08-13

Family

ID=8102935

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG136298A EG23791A (en)	1997-11-07	1998-11-03	1-(4-(1-4-Fluorophenyl-1H-indole-3-yl-1-butyl spiro (isobenzofuran 1-(3H), 4-Piperidine) hydrohalogenides

Country Status (39)

Country	Link
US (2)	US6844352B2 (ja)
EP (1)	EP1044202B1 (ja)
JP (1)	JP3605358B2 (ja)
KR (1)	KR100399274B1 (ja)
CN (1)	CN1105115C (ja)
AR (1)	AR023010A1 (ja)
AT (1)	ATE288918T1 (ja)
AU (1)	AU749094B2 (ja)
BG (1)	BG64906B1 (ja)
BR (1)	BR9813949A (ja)
CA (1)	CA2308745C (ja)
CZ (1)	CZ288666B6 (ja)
DE (1)	DE69828999T2 (ja)
DZ (1)	DZ2642A1 (ja)
EA (1)	EA002092B1 (ja)
EG (1)	EG23791A (ja)
ES (1)	ES2234162T3 (ja)
HK (1)	HK1034075A1 (ja)
HR (1)	HRP20000261B1 (ja)
HU (1)	HUP0100991A3 (ja)
ID (1)	ID25776A (ja)
IL (1)	IL135723A (ja)
IS (1)	IS2342B (ja)
JO (1)	JO2052B1 (ja)
MA (1)	MA25585A1 (ja)
NO (1)	NO325920B1 (ja)
NZ (1)	NZ504065A (ja)
PE (1)	PE130299A1 (ja)
PL (1)	PL190538B1 (ja)
PT (1)	PT1044202E (ja)
RS (1)	RS49777B (ja)
SK (1)	SK285245B6 (ja)
TN (1)	TNSN98201A1 (ja)
TR (1)	TR200001267T2 (ja)
TW (1)	TW483894B (ja)
UA (1)	UA64769C2 (ja)
UY (1)	UY25236A1 (ja)
WO (1)	WO1999024436A1 (ja)
ZA (1)	ZA9810116B (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR030453A1 (es) *	2000-08-15	2003-08-20	Lundbeck & Co As H	Composicion farmaceutica con contenido de 1' [4-[1-(4-fluorofenil)-1h-indol-3-il]-1-butil] espiro [isobenzofuran-1 (3h), 4'-piperidina]
AU2003263155A1 (en) *	2002-09-20	2004-04-08	H. Lundbeck A/S	Method for manufacture of dihydroisobenzofuran derivatives
US7863272B2 (en)	2003-06-12	2011-01-04	M's Science Corporation	Sigma ligands for neuronal regeneration and functional recovery
US20090306341A1 (en) *	2005-07-29	2009-12-10	Joachim Emmert	LC/MS Blends Containing Ionizing Additives
WO2007047978A2 (en)	2005-10-21	2007-04-26	Braincells, Inc.	Modulation of neurogenesis by pde inhibition
EP2314289A1 (en)	2005-10-31	2011-04-27	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) *	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
US20070244143A1 (en) *	2006-03-08	2007-10-18	Braincells, Inc	Modulation of neurogenesis by nootropic agents
US20100009983A1 (en) *	2006-05-09	2010-01-14	Braincells, Inc.	5 ht receptor mediated neurogenesis
CA2651813A1 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
US7678808B2 (en) *	2006-05-09	2010-03-16	Braincells, Inc.	5 HT receptor mediated neurogenesis
EP2068872A1 (en) *	2006-09-08	2009-06-17	Braincells, Inc.	Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
CA2663347A1 (en) *	2006-09-19	2008-03-27	Braincells, Inc.	Ppar mediated modulation of neurogenesis
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5109002A (en) *	1989-09-08	1992-04-28	Du Pont Merck Pharmaceutical Company	Antipsychotic 1-cycloalkylpiperidines
NZ243065A (en) *	1991-06-13	1995-07-26	Lundbeck & Co As H	Piperidine derivatives and pharmaceutical compositions

1998
- 1998-06-11 UA UA2000052828A patent/UA64769C2/uk unknown
- 1998-10-20 TW TW087117299A patent/TW483894B/zh not_active IP Right Cessation
- 1998-10-27 MA MA25316A patent/MA25585A1/fr unknown
- 1998-11-03 EG EG136298A patent/EG23791A/xx active
- 1998-11-04 TN TNTNSN98201A patent/TNSN98201A1/fr unknown
- 1998-11-04 DZ DZ980252A patent/DZ2642A1/xx active
- 1998-11-05 ZA ZA9810116A patent/ZA9810116B/xx unknown
- 1998-11-05 JO JO19982052A patent/JO2052B1/en active
- 1998-11-05 PE PE1998001067A patent/PE130299A1/es not_active Application Discontinuation
- 1998-11-05 AR ARP980105596A patent/AR023010A1/es active IP Right Grant
- 1998-11-06 RS YUP-235/00A patent/RS49777B/sr unknown
- 1998-11-06 KR KR10-2000-7004858A patent/KR100399274B1/ko not_active IP Right Cessation
- 1998-11-06 NZ NZ504065A patent/NZ504065A/en unknown
- 1998-11-06 WO PCT/DK1998/000480 patent/WO1999024436A1/en active IP Right Grant
- 1998-11-06 DE DE69828999T patent/DE69828999T2/de not_active Expired - Fee Related
- 1998-11-06 CN CN98810910A patent/CN1105115C/zh not_active Expired - Fee Related
- 1998-11-06 CZ CZ20001663A patent/CZ288666B6/cs not_active IP Right Cessation
- 1998-11-06 PT PT98952580T patent/PT1044202E/pt unknown
- 1998-11-06 CA CA002308745A patent/CA2308745C/en not_active Expired - Fee Related
- 1998-11-06 JP JP2000520446A patent/JP3605358B2/ja not_active Expired - Fee Related
- 1998-11-06 AT AT98952580T patent/ATE288918T1/de not_active IP Right Cessation
- 1998-11-06 HU HU0100991A patent/HUP0100991A3/hu unknown
- 1998-11-06 IL IL13572398A patent/IL135723A/xx not_active IP Right Cessation
- 1998-11-06 EP EP98952580A patent/EP1044202B1/en not_active Expired - Lifetime
- 1998-11-06 BR BR9813949-5A patent/BR9813949A/pt not_active Application Discontinuation
- 1998-11-06 ID IDW20000997D patent/ID25776A/id unknown
- 1998-11-06 EA EA200000502A patent/EA002092B1/ru not_active IP Right Cessation
- 1998-11-06 UY UY25236A patent/UY25236A1/es not_active IP Right Cessation
- 1998-11-06 TR TR2000/01267T patent/TR200001267T2/xx unknown
- 1998-11-06 AU AU10226/99A patent/AU749094B2/en not_active Ceased
- 1998-11-06 SK SK646-2000A patent/SK285245B6/sk not_active IP Right Cessation
- 1998-11-06 ES ES98952580T patent/ES2234162T3/es not_active Expired - Lifetime
- 1998-11-06 PL PL98340220A patent/PL190538B1/pl not_active IP Right Cessation
2000
- 2000-04-18 IS IS5460A patent/IS2342B/is unknown
- 2000-04-27 NO NO20002188A patent/NO325920B1/no not_active IP Right Cessation
- 2000-05-04 HR HR20000261A patent/HRP20000261B1/xx not_active IP Right Cessation
- 2000-05-29 BG BG104485A patent/BG64906B1/bg unknown
2001
- 2001-06-28 HK HK01104490A patent/HK1034075A1/xx not_active IP Right Cessation
2002
- 2002-10-15 US US10/272,403 patent/US6844352B2/en not_active Expired - Fee Related
2004
- 2004-12-13 US US11/012,084 patent/US20050171135A1/en not_active Abandoned

Also Published As

Publication number	Publication date
ES2234162T3 (es)	2005-06-16
EA200000502A1 (ru)	2000-10-30
IS2342B (is)	2008-02-15
CZ288666B6 (cs)	2001-08-15
NO20002188L (no)	2000-06-14
BG104485A (en)	2001-01-31
SK6462000A3 (en)	2000-10-09
DE69828999D1 (de)	2005-03-17
IL135723A0 (en)	2001-05-20
JP3605358B2 (ja)	2004-12-22
PL340220A1 (en)	2001-01-15
HRP20000261B1 (en)	2009-04-30
CA2308745A1 (en)	1999-05-20
NO325920B1 (no)	2008-08-18
CN1105115C (zh)	2003-04-09
PT1044202E (pt)	2005-04-29
AU1022699A (en)	1999-05-31
HUP0100991A3 (en)	2003-03-28
CN1278823A (zh)	2001-01-03
HRP20000261A2 (en)	2001-04-30
PL190538B1 (pl)	2005-12-30
NO20002188D0 (no)	2000-04-27
AU749094B2 (en)	2002-06-20
TR200001267T2 (tr)	2000-09-21
CZ20001663A3 (cs)	2000-10-11
HK1034075A1 (en)	2001-10-12
US20050171135A1 (en)	2005-08-04
NZ504065A (en)	2002-05-31
RS49777B (sr)	2008-06-05
AR023010A1 (es)	2002-09-04
ZA9810116B (en)	1999-05-07
EP1044202A1 (en)	2000-10-18
TW483894B (en)	2002-04-21
TNSN98201A1 (fr)	2005-03-15
KR100399274B1 (ko)	2003-09-26
BG64906B1 (bg)	2006-08-31
JP2001522852A (ja)	2001-11-20
IL135723A (en)	2005-11-20
JO2052B1 (en)	1999-05-15
US20030055074A1 (en)	2003-03-20
EP1044202B1 (en)	2005-02-09
BR9813949A (pt)	2000-09-26
UA64769C2 (uk)	2004-03-15
EA002092B1 (ru)	2001-12-24
US6844352B2 (en)	2005-01-18
YU23500A (sh)	2003-12-31
DZ2642A1 (fr)	2004-12-28
KR20010031791A (ko)	2001-04-16
PE130299A1 (es)	1999-12-16
ID25776A (id)	2000-11-02
IS5460A (is)	2000-04-18
CA2308745C (en)	2004-01-20
ATE288918T1 (de)	2005-02-15
WO1999024436A1 (en)	1999-05-20
HUP0100991A2 (hu)	2001-09-28
DE69828999T2 (de)	2005-07-21
MA25585A1 (fr)	2002-12-31
UY25236A1 (es)	2000-12-29
SK285245B6 (sk)	2006-09-07

Publication	Publication Date	Title
ZA9610885B (en)	1998-06-23	1-(1,2-disubstituted piperidinyl)-4-substituted piperidine derivatives.
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ZA965935B (en)	1998-02-12	Heterocyclic compounds.
PL330042A1 (en)	1999-04-26	Novel 2,3-disubstituted 4(3h)-quinazolynones
ZA989767B (en)	2000-04-28	Novel compounds.
EG23791A (en)	2007-08-13	1-(4-(1-4-Fluorophenyl-1H-indole-3-yl-1-butyl spiro (isobenzofuran 1-(3H), 4-Piperidine) hydrohalogenides
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AU2517299A (en)	1999-08-02	Substituted alpha,beta-anellated butyrolactones
ZA200101830B (en)	2002-06-05	Piperidine derivatives.
ZA9811725B (en)	2000-06-27	Triazine compounds.
ZA9811758B (en)	2000-06-22	Novel compounds.
GB2297749B (en)	1998-07-01	1-[2-(substituted vinyl)]-3-4--dihydro-5h-2,3-benzodiazepine derivatives
ZA9811503B (en)	2000-06-15	Novel compounds.
ZA989826B (en)	2000-04-28	Peroxynitrate based bleaching systems.
ZA987B (en)	1999-07-02	Substituted 4-benzoylpyrazoles.
ZA98868B (en)	1999-08-03	Novel compounds.
ZA979781B (en)	1998-06-08	Piperidine derivatives.
IL133919A0 (en)	2001-04-30	2,4,4-trisubstituted-1,3-dioxolane antifungals