EE05179B1 - Anticholinergics used as medicaments and a process for their preparation - Google Patents

Anticholinergics used as medicaments and a process for their preparation

Info

Publication number: EE05179B1
Authority: EE; Estonia
Prior art keywords: medicaments; preparation; anticholinergics used; anticholinergics
Prior art date: 2000-10-14

Application number

EEP200300151A

Other languages

Estonian (et)

Inventor

Meissner Helmut

Morschh�user Gerd

Paul Pieper Michael

Pohl Gerald

Reichl Richard

Speck Georg

Banholzer Rolf

Original Assignee

Boehringer Ingelheim Pharma Gmbh & Co. Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-14

Filing date

2001-09-28

Publication date

2009-06-15

2001-09-28 Application filed by Boehringer Ingelheim Pharma Gmbh & Co. Kg filed Critical Boehringer Ingelheim Pharma Gmbh & Co. Kg

2003-06-16 Publication of EE200300151A publication Critical patent/EE200300151A/en

2009-06-15 Publication of EE05179B1 publication Critical patent/EE05179B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Cardiology (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Hydrogenated Pyridines (AREA)

EEP200300151A 2000-10-14 2001-09-28 Anticholinergics used as medicaments and a process for their preparation EE05179B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10050994A DE10050994A1 (en)	2000-10-14	2000-10-14	New diphenylalkanoic acid azabicyclooctane ester quaternary salts useful as anticholinergic agents, especially in treatment of asthma and chronic obstructive pulmonary disease
PCT/EP2001/011226 WO2002032899A1 (en)	2000-10-14	2001-09-28	Novel anticholinergic agents that can be used as medicaments and method for the production thereof

Publications (2)

Publication Number	Publication Date
EE200300151A EE200300151A (en)	2003-06-16
EE05179B1 true EE05179B1 (en)	2009-06-15

Family

ID=7659808

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200300151A EE05179B1 (en)	2000-10-14	2001-09-28	Anticholinergics used as medicaments and a process for their preparation

Country Status (38)

Country	Link
EP (2)	EP1325001B1 (en)
JP (2)	JP4109106B2 (en)
KR (1)	KR100830359B1 (en)
CN (1)	CN1275962C (en)
AR (1)	AR035589A1 (en)
AT (1)	ATE259805T1 (en)
AU (2)	AU2002213975B2 (en)
BG (1)	BG66225B1 (en)
BR (1)	BR0114635A (en)
CA (1)	CA2425557C (en)
DE (2)	DE10050994A1 (en)
DK (1)	DK1325001T3 (en)
EA (1)	EA005816B1 (en)
EC (1)	ECSP034542A (en)
EE (1)	EE05179B1 (en)
ES (1)	ES2215147T3 (en)
HK (1)	HK1060566A1 (en)
HR (1)	HRP20030278B1 (en)
HU (1)	HUP0301203A3 (en)
IL (2)	IL155334A0 (en)
ME (1)	MEP39908A (en)
MX (1)	MXPA03003160A (en)
MY (1)	MY127144A (en)
NO (1)	NO328207B1 (en)
NZ (1)	NZ525836A (en)
PE (1)	PE20020433A1 (en)
PL (1)	PL207311B1 (en)
PT (1)	PT1325001E (en)
RS (1)	RS50464B (en)
SA (1)	SA01220414B1 (en)
SI (1)	SI1325001T1 (en)
SK (1)	SK287138B6 (en)
TR (1)	TR200400376T4 (en)
TW (1)	TWI306098B (en)
UA (1)	UA73804C2 (en)
UY (1)	UY26958A1 (en)
WO (1)	WO2002032899A1 (en)
ZA (1)	ZA200302914B (en)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10200943A1 (en) *	2002-01-12	2003-07-24	Boehringer Ingelheim Pharma	Process for the preparation of scopine esters
DE10203753A1 (en) *	2002-01-31	2003-08-14	Boehringer Ingelheim Pharma	New xanthene carboxylic acid esters, processes for their preparation and their use as medicines
US7405224B2 (en)	2002-01-31	2008-07-29	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions
DE10256317A1 (en) *	2002-04-12	2003-10-23	Boehringer Ingelheim Pharma	Synergistic medicaments used for treating inflammaSynergistic medicaments used for treating inflammatory or obstructive respiratory tract diseases, cotory or obstructive respiratory tract diseases, contain quaternized scopine ester anticholinergic agntain quaternized scopine ester anticholinergic agent and beta-mimetic agent e.g. salmeterol salt ent and beta-mimetic agent e.g. salmeterol salt
US7084153B2 (en)	2002-04-12	2006-08-01	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Medicaments comprising steroids and a novel anticholinergic
DE10216429A1 (en) *	2002-04-12	2003-10-23	Boehringer Ingelheim Pharma	Synergistic medicaments for treating inflammatory or obstructive respiratory tract diseases, containing quaternized scopine ester anticholinergic agent and steroid, e.g. budesonide
NZ536337A (en) *	2002-04-12	2007-05-31	Boehringer Ingelheim Pharma	Medicaments containing betamimetic drugs and a novel anticholinesterase drug
US7417051B2 (en)	2002-04-12	2008-08-26	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Medicaments comprising betamimetics and a novel anticholinergic
DE10224091A1 (en) *	2002-05-31	2003-12-11	Boehringer Ingelheim Pharma	Technical process for the production of tropenol
DE10230750A1 (en) *	2002-07-09	2004-01-22	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New drug compositions based on new anticholonergics and NK1 receptor antagonists
DE10230769A1 (en) *	2002-07-09	2004-01-22	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New drug compositions based on new anticholinergics and PDE-IV inhibitors
ATE349210T1 (en) *	2002-07-09	2007-01-15	Boehringer Ingelheim Pharma	PHARMACEUTICAL COMPOSITIONS OF ANTICHOLINERGICS AND P38 KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES
DE10230751A1 (en)	2002-07-09	2004-01-22	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New drug compositions based on new anticholinergics and EGFR kinase inhibitors
DK1530464T3 (en) *	2002-08-14	2008-09-08	Boehringer Ingelheim Pharma	Aerosol formulation for inhalation containing an anticholinergic
US7244742B2 (en)	2002-08-17	2007-07-17	Boehringer Ingelheim Pharma Gmbh & Co Kg	Pharmaceutical compositions for inhalation containing an anticholinergic, corticosteroid and betamimetic
DE10237739A1 (en) *	2002-08-17	2004-02-26	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Inhalable medicament for treating inflammatory or obstructive respiratory diseases, containing synergistic combination of tropane derivative anticholinergic agent, corticosteroid and beta-mimetic agent
US7056916B2 (en)	2002-11-15	2006-06-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Medicaments for the treatment of chronic obstructive pulmonary disease
DE10317461A1 (en)	2003-04-16	2004-10-28	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Preparing microparticles labeled with technetium, useful as powders for inhalation, e.g. to study deposition of pharmaceuticals, such as anticholinergic agents, involves incubation with solution of technetium salt
DE10323966A1 (en) *	2003-05-27	2004-12-16	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New long-acting drug combinations for the treatment of respiratory diseases
US7332175B2 (en)	2003-05-27	2008-02-19	Boehringer Ingelheim International Gmbh	Long-acting drug combinations for the treatment of respiratory complaints
US7273603B2 (en) *	2003-07-11	2007-09-25	Boehringer Ingelheim International Gmbh	HFC solution formulations containing an anticholinergic
US7462367B2 (en)	2003-07-11	2008-12-09	Boehringer Ingelheim International Gmbh	Anticholinergic powder formulations for inhalation
DE10331350A1 (en) *	2003-07-11	2005-01-27	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Inhalation powder useful for treating respiratory diseases comprises a 9,9-dimethyl-7-(2,2-diphenylpropionyloxy)-3-oxa-9-azatricyclononane salt and a finely divided excipient
WO2005013992A1 (en) *	2003-07-28	2005-02-17	Boehringer Ingelheim International Gmbh	Medicaments for inhalation comprising betamimetics and an anticholinergic agent
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ES2326320T3 (en) *	2003-07-28	2009-10-07	Boehringer Ingelheim International Gmbh	INHALATION DRUGS THAT INCLUDE STEROIDS AND NEW ESTER OF FLUORENCARBOXILIC ACID.
JP2007500676A (en) *	2003-07-31	2007-01-18	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Inhalable drugs including anticholinergics and beta receptor stimulants
EP1504756A1 (en) *	2003-08-06	2005-02-09	Kyowa Hakko Kogyo Co., Ltd	Medicament compositions comprising a heterocyclic compound and an anticholinergic
DE10345065A1 (en)	2003-09-26	2005-04-14	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Aerosol formulation for inhalation containing an anticholinergic
EP1706118A1 (en) *	2004-01-09	2006-10-04	Boehringer Ingelheim International GmbH	New pharmaceutical compositions based on a scopineester and nicotinamide derivatives
US7507745B2 (en)	2004-02-20	2009-03-24	Boehringer Ingelheim International Gmbh	Pharmaceutical compositions based on fluorenecarboxylic acid esters and soluble TNF receptor fusion proteins
JP2007523116A (en) *	2004-02-20	2007-08-16	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	NOVEL PHARMACEUTICAL COMPOSITION BASED ON ANTICHOLINIC AGONIST AND PEGSUNERCEPT
US20050186175A1 (en) *	2004-02-20	2005-08-25	Boehringer Ingelheim International Gmbh	Pharmaceutical compositions based on benzilic acid esters and soluble TNF receptor fusion proteins
DE102004016179A1 (en) *	2004-03-30	2005-10-20	Boehringer Ingelheim Pharma	Compounds for the treatment of proliferative processes
US7220742B2 (en)	2004-05-14	2007-05-22	Boehringer Ingelheim International Gmbh	Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
ATE427108T1 (en) *	2004-08-11	2009-04-15	Boehringer Ingelheim Pharma	MEDICINAL PRODUCTS CONTAINING ANTICHOLINERGICS FOR THE TREATMENT OF DISEASES OF THE URINARY TRACT
DE102004056578A1 (en) *	2004-11-23	2006-05-24	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Inhaled drugs containing a new anticholinergic, formoterol and a steroid
EP1855689A1 (en) *	2005-02-16	2007-11-21	Boehringer Ingelheim International GmbH	Pharmaceutical compositions comprising anticholinergics and etiprednol
CA2600636A1 (en) *	2005-03-09	2006-09-14	Boehringer Ingelheim International Gmbh	New pharmaceutical compositions based on anticholinergics and pde 5-inhibitors
JP2008542332A (en) *	2005-05-31	2008-11-27	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Novel pharmaceutical composition for the treatment of respiratory diseases
EP1898894A1 (en) *	2005-06-17	2008-03-19	Boehringer Ingelheim International GmbH	Mrp iv inhibitors for the treatment of respiratory diseases
DE102005030733A1 (en)	2005-07-01	2007-01-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New drug combinations for the treatment of respiratory diseases containing long-acting beta-2 agonists and at least one other active ingredient
JP5270343B2 (en)	2005-08-15	2013-08-21	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Beta mimetic manufacturing method
BRPI0617674A2 (en)	2005-10-19	2011-08-02	Ranbaxy Lab Ltd	pharmaceutical compositions and their uses
DE102005055963A1 (en) *	2005-11-24	2007-07-19	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Aerosol formulation for inhalation containing an anticholinergic
DE102005055961A1 (en) *	2005-11-24	2007-05-31	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pharmaceutical composition containing specific concentration of quaternary ammonium anticholinergic agent, useful for treatment, by inhalation, of respiratory tract diseases
DE102005055957A1 (en) *	2005-11-24	2007-07-12	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Aerosol formulation for inhalation containing an anticholinergic
CA2660186A1 (en)	2006-08-07	2008-02-14	Boehringer Ingelheim International Gmbh	Pharmaceutical combinations for the treatment of respiratory diseases
EP1958947A1 (en)	2007-02-15	2008-08-20	Ranbaxy Laboratories Limited	Inhibitors of phosphodiesterase type 4
MX2009009793A (en)	2007-03-14	2009-10-16	Ranbaxy Lab Ltd	Pyrazolo (3, 4-b) pyridine derivatives as phosphodiesterase inhibitors.
ES2569359T3 (en)	2007-07-06	2016-05-10	Vectura Delivery Devices Limited	Inhaler
US20100234411A1 (en) *	2007-07-18	2010-09-16	Boehringer Ingelheim Intermational Gmbh	New Combination for the Treatment of Respiratory Diseases
EP2077132A1 (en)	2008-01-02	2009-07-08	Boehringer Ingelheim Pharma GmbH & Co. KG	Dispensing device, storage device and method for dispensing a formulation
EP2082771A1 (en)	2008-01-24	2009-07-29	Vectura Delivery Devices Limited	Inhaler
EP2082766A1 (en)	2008-01-24	2009-07-29	Vectura Delivery Devices Limited	Blister Strip Coil Forming
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EP2082767A1 (en)	2008-01-24	2009-07-29	Vectura Delivery Devices Limited	Inhaler
EP2111861A1 (en)	2008-04-21	2009-10-28	Ranbaxy Laboratories Limited	Compositions of phosphodiesterase type IV inhibitors
EP2662472B1 (en)	2009-03-31	2019-02-27	Boehringer Ingelheim International Gmbh	Method for coating a surface of a component
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GB0918450D0 (en)	2009-10-21	2009-12-09	Innovata Ltd	Composition
EP2504051B1 (en)	2009-11-25	2019-09-04	Boehringer Ingelheim International GmbH	Nebulizer
WO2011064164A1 (en)	2009-11-25	2011-06-03	Boehringer Ingelheim International Gmbh	Nebulizer
US10016568B2 (en)	2009-11-25	2018-07-10	Boehringer Ingelheim International Gmbh	Nebulizer
EP2585151B1 (en)	2010-06-24	2018-04-04	Boehringer Ingelheim International GmbH	Nebulizer
EP2694220B1 (en)	2011-04-01	2020-05-06	Boehringer Ingelheim International GmbH	Medical device comprising a container
US9827384B2 (en)	2011-05-23	2017-11-28	Boehringer Ingelheim International Gmbh	Nebulizer
WO2013152894A1 (en)	2012-04-13	2013-10-17	Boehringer Ingelheim International Gmbh	Atomiser with coding means
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WO2015018904A1 (en)	2013-08-09	2015-02-12	Boehringer Ingelheim International Gmbh	Nebulizer
ES2836977T3 (en)	2013-08-09	2021-06-28	Boehringer Ingelheim Int	Nebulizer
PL3139981T3 (en)	2014-05-07	2021-06-14	Boehringer Ingelheim International Gmbh	Nebulizer
DK3139984T3 (en)	2014-05-07	2021-07-19	Boehringer Ingelheim Int	Atomizer
WO2015169732A1 (en)	2014-05-07	2015-11-12	Boehringer Ingelheim International Gmbh	Container, nebulizer and use
AU2015276310B2 (en) *	2014-06-18	2020-01-16	Boehringer Ingelheim Vetmedica Gmbh	Muscarinic antagonists and combinations thereof for the treatment of airway disease in horses
CA2997545C (en) *	2015-09-04	2022-01-11	Janssen Pharmaceutica Nv	Therapeutic compounds for pain and synthesis thereof
CN113292574B (en) *	2020-02-21	2022-05-03	四川大学	Chiral polycyclic tropane compounds, preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4003270A1 (en) *	1990-02-03	1991-08-08	Boehringer Ingelheim Kg	NEW SPEED GASES AND THEIR USE IN MEDICINE PREPARATIONS
DE4108393A1 (en) *	1991-03-15	1992-09-17	Boehringer Ingelheim Kg	NEW ESTERS BI-AND TRICYCLIC AMINO ALCOHOLS, THEIR PREPARATION AND THEIR USE IN MEDICINAL PRODUCTS

2000
- 2000-10-14 DE DE10050994A patent/DE10050994A1/en not_active Withdrawn
2001
- 2001-09-28 IL IL15533401A patent/IL155334A0/en active IP Right Grant
- 2001-09-28 ME MEP-399/08A patent/MEP39908A/en unknown
- 2001-09-28 ES ES01982374T patent/ES2215147T3/en not_active Expired - Lifetime
- 2001-09-28 JP JP2002536281A patent/JP4109106B2/en not_active Expired - Lifetime
- 2001-09-28 KR KR1020037005256A patent/KR100830359B1/en not_active IP Right Cessation
- 2001-09-28 AU AU2002213975A patent/AU2002213975B2/en not_active Expired
- 2001-09-28 RS YUP-295/03A patent/RS50464B/en unknown
- 2001-09-28 AU AU1397502A patent/AU1397502A/en active Pending
- 2001-09-28 EP EP01982374A patent/EP1325001B1/en not_active Expired - Lifetime
- 2001-09-28 PT PT01982374T patent/PT1325001E/en unknown
- 2001-09-28 SK SK435-2003A patent/SK287138B6/en not_active IP Right Cessation
- 2001-09-28 EE EEP200300151A patent/EE05179B1/en not_active IP Right Cessation
- 2001-09-28 MX MXPA03003160A patent/MXPA03003160A/en active IP Right Grant
- 2001-09-28 AT AT01982374T patent/ATE259805T1/en active
- 2001-09-28 NZ NZ525836A patent/NZ525836A/en not_active IP Right Cessation
- 2001-09-28 CN CNB018171443A patent/CN1275962C/en not_active Expired - Lifetime
- 2001-09-28 DE DE50101524T patent/DE50101524D1/en not_active Expired - Lifetime
- 2001-09-28 DK DK01982374T patent/DK1325001T3/en active
- 2001-09-28 CA CA002425557A patent/CA2425557C/en not_active Expired - Lifetime
- 2001-09-28 BR BR0114635-1A patent/BR0114635A/en not_active Expired - Fee Related
- 2001-09-28 WO PCT/EP2001/011226 patent/WO2002032899A1/en active IP Right Grant
- 2001-09-28 SI SI200130085T patent/SI1325001T1/en unknown
- 2001-09-28 PL PL360673A patent/PL207311B1/en not_active IP Right Cessation
- 2001-09-28 TR TR2004/00376T patent/TR200400376T4/en unknown
- 2001-09-28 HU HU0301203A patent/HUP0301203A3/en unknown
- 2001-09-28 EP EP03023933A patent/EP1382606A3/en not_active Withdrawn
- 2001-09-28 EA EA200300459A patent/EA005816B1/en not_active IP Right Cessation
- 2001-09-28 UA UA2003054186A patent/UA73804C2/en unknown
- 2001-10-02 SA SA01220414A patent/SA01220414B1/en unknown
- 2001-10-10 UY UY26958A patent/UY26958A1/en not_active Application Discontinuation
- 2001-10-12 TW TW090125220A patent/TWI306098B/en not_active IP Right Cessation
- 2001-10-12 MY MYPI20014765A patent/MY127144A/en unknown
- 2001-10-12 PE PE2001001018A patent/PE20020433A1/en not_active Application Discontinuation
- 2001-10-12 AR ARP010104785A patent/AR035589A1/en active Pending
2003
- 2003-03-28 BG BG107688A patent/BG66225B1/en active Active
- 2003-04-07 EC EC2003004542A patent/ECSP034542A/en unknown
- 2003-04-10 IL IL155334A patent/IL155334A/en not_active IP Right Cessation
- 2003-04-11 ZA ZA200302914A patent/ZA200302914B/en unknown
- 2003-04-11 HR HR20030278A patent/HRP20030278B1/en not_active IP Right Cessation
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2004
- 2004-05-20 HK HK04103582A patent/HK1060566A1/en not_active IP Right Cessation
2008
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Also Published As

Publication number	Publication date
EP1382606A3 (en)	2004-10-13
CA2425557A1 (en)	2003-04-11
SA01220414B1 (en)	2007-01-20
JP2004511557A (en)	2004-04-15
EE200300151A (en)	2003-06-16
WO2002032899A1 (en)	2002-04-25
TR200400376T4 (en)	2004-03-22
MY127144A (en)	2006-11-30
BR0114635A (en)	2004-02-10
ZA200302914B (en)	2003-11-14
DK1325001T3 (en)	2004-06-21
BG66225B1 (en)	2012-06-29
SI1325001T1 (en)	2004-08-31
TWI306098B (en)	2009-02-11
ATE259805T1 (en)	2004-03-15
UY26958A1 (en)	2002-06-20
NO20031693D0 (en)	2003-04-11
ECSP034542A (en)	2003-06-25
NO20031693L (en)	2003-05-28
PE20020433A1 (en)	2002-06-28
HRP20030278B1 (en)	2006-02-28
KR20030041165A (en)	2003-05-23
EA005816B1 (en)	2005-06-30
EP1382606A2 (en)	2004-01-21
HUP0301203A2 (en)	2003-10-28
PL207311B1 (en)	2010-11-30
CA2425557C (en)	2007-11-13
CN1468236A (en)	2004-01-14
NO328207B1 (en)	2010-01-11
JP4109106B2 (en)	2008-07-02
BG107688A (en)	2003-09-30
KR100830359B1 (en)	2008-05-20
AR035589A1 (en)	2004-06-16
HK1060566A1 (en)	2004-08-13
CN1275962C (en)	2006-09-20
AU2002213975B2 (en)	2006-11-09
PT1325001E (en)	2004-07-30
UA73804C2 (en)	2005-09-15
MEP39908A (en)	2011-02-10
RS50464B (en)	2010-03-02
YU29503A (en)	2006-03-03
EP1325001B1 (en)	2004-02-18
HUP0301203A3 (en)	2006-05-29
PL360673A1 (en)	2004-09-20
EP1325001A1 (en)	2003-07-09
SK4352003A3 (en)	2003-08-05
IL155334A0 (en)	2003-11-23
JP2008120834A (en)	2008-05-29
AU1397502A (en)	2002-04-29
DE10050994A1 (en)	2002-04-18
EA200300459A1 (en)	2003-10-30
DE50101524D1 (en)	2004-03-25
HRP20030278A2 (en)	2005-02-28
MXPA03003160A (en)	2005-09-09
SK287138B6 (en)	2010-01-07
ES2215147T3 (en)	2004-10-01
NZ525836A (en)	2004-09-24
IL155334A (en)	2009-02-11

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Legal Events

Date	Code	Title	Description
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2014-06-16	MM4A	Lapsed by not paying the annual fees	Effective date: 20130928