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EA202092990A2 - Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу - Google Patents

Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу

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Publication number
EA202092990A2
EA202092990A2 EA202092990A EA202092990A EA202092990A2 EA 202092990 A2 EA202092990 A2 EA 202092990A2 EA 202092990 A EA202092990 A EA 202092990A EA 202092990 A EA202092990 A EA 202092990A EA 202092990 A2 EA202092990 A2 EA 202092990A2
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EA
Eurasian Patent Office
Prior art keywords
hepatitis
core protein
nucleic acid
vaccine containing
virus core
Prior art date
Application number
EA202092990A
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English (en)
Other versions
EA202092990A3 (ru
Inventor
Дэвид Б. Уэйнер
Цзянь Янь
Ниямекие Обенг-Аджей
Original Assignee
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания
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Application filed by Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания filed Critical Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания
Publication of EA202092990A2 publication Critical patent/EA202092990A2/ru
Publication of EA202092990A3 publication Critical patent/EA202092990A3/ru

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    • A—HUMAN NECESSITIES
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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    • C12N2730/00011—Details
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

В данной заявке предложены нуклеотидные последовательности, которые кодируют новую консенсусную аминокислотную последовательность корового белка вируса гепатита B (HBV), а также генетические конструкции (векторы) и вакцины, которые экспрессируют указанные белковые последовательности. Также в данной заявке предложены способы индукции иммунного ответа на HBV с использованием предложенных нуклеотидных последовательностей.
EA202092990A 2011-02-11 2012-02-13 Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу EA202092990A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161442162P 2011-02-11 2011-02-11

Publications (2)

Publication Number Publication Date
EA202092990A2 true EA202092990A2 (ru) 2021-04-30
EA202092990A3 EA202092990A3 (ru) 2021-07-30

Family

ID=46638994

Family Applications (3)

Application Number Title Priority Date Filing Date
EA201391160A EA032364B1 (ru) 2011-02-11 2012-02-13 Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу
EA202092990A EA202092990A3 (ru) 2011-02-11 2012-02-13 Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу
EA201892795A EA037377B1 (ru) 2011-02-11 2012-02-13 Вакцина для индукции иммунного ответа на hbv

Family Applications Before (1)

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EA201391160A EA032364B1 (ru) 2011-02-11 2012-02-13 Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу

Family Applications After (1)

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EA201892795A EA037377B1 (ru) 2011-02-11 2012-02-13 Вакцина для индукции иммунного ответа на hbv

Country Status (15)

Country Link
US (3) US9403879B2 (ru)
EP (2) EP3760227A1 (ru)
JP (2) JP6153473B2 (ru)
KR (1) KR101942372B1 (ru)
CN (1) CN103442732B (ru)
AU (1) AU2012214141B2 (ru)
CA (1) CA2827080C (ru)
EA (3) EA032364B1 (ru)
ES (1) ES2806263T3 (ru)
HU (1) HUE049669T2 (ru)
MX (1) MX343830B (ru)
PL (1) PL2672992T3 (ru)
PT (1) PT2672992T (ru)
WO (1) WO2012109668A1 (ru)
ZA (1) ZA201306009B (ru)

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MX2013009274A (es) 2013-09-06
US20160317652A1 (en) 2016-11-03
CN103442732A (zh) 2013-12-11
US9403879B2 (en) 2016-08-02
PL2672992T3 (pl) 2020-11-02
AU2012214141B2 (en) 2016-01-28
WO2012109668A1 (en) 2012-08-16
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CA2827080A1 (en) 2012-08-16
EP2672992B1 (en) 2020-04-08
PT2672992T (pt) 2020-07-27
EA201391160A1 (ru) 2013-12-30
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MX343830B (es) 2016-11-24
EA032364B1 (ru) 2019-05-31
EA037377B1 (ru) 2021-03-22
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US10695421B2 (en) 2020-06-30
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